Cephalothin Sodium (BioDeep_00001868434)

Main id: BioDeep_00000015168

 


代谢物信息卡片


Cephalothin Sodium

化学式: C16H15N2NaO6S2 (418.026921)
中文名称: 先锋霉素 钠盐
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CC3=CC=CS3)SC1)C(=O)[O-].[Na+]
InChI: /q

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

1 个代谢物同义名

Cephalothin Sodium



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Patrícia Aleixa do Nascimento, Ana Carolina Kogawa, Hérida Regina Nunes Salgado. Cephalothin: Review of Characteristics, Properties, and Status of Analytical Methods. Journal of AOAC International. 2021 Dec; 104(6):1593-1608. doi: 10.1093/jaoacint/qsaa163. [PMID: 33252646]
  • Taisuke Kuroda, Yohei Minamijima, Hidekazu Niwa, Norihisa Tamura, Hiroshi Mita, Kentaro Fukuda, Masahiro Kaimachi, Yuto Suzuki, Yuki Enoki, Kazuaki Taguchi, Kazuaki Matsumoto, Pierre-Louis Toutain, Alain Bousquet-Melou, Yoshinori Kasashima. Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses. Equine veterinary journal. 2021 Nov; 53(6):1239-1249. doi: 10.1111/evj.13406. [PMID: 33341979]
  • Zhengyu Zhang, Masanori Tachikawa, Yasuo Uchida, Tetsuya Terasaki. Drug Clearance from Cerebrospinal Fluid Mediated by Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) at Arachnoid Membrane of Rats. Molecular pharmaceutics. 2018 03; 15(3):911-922. doi: 10.1021/acs.molpharmaceut.7b00852. [PMID: 29436232]
  • Valerie Corvalán, Beatrice Hervé, Camila Sanhueza, Nicolás Martínez, María Almonacid, Sebastián De La Fuente. [Susceptibility to first-generation Cephalosporins in Enterobacteriaceae isolated from urine culture according to CLSI and EUCAST breakpoints]. Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia. 2018 ; 35(3):329-331. doi: 10.4067/s0716-10182018000300329. [PMID: 30534916]
  • Darren M Roberts, Dwarakanathan Ranganathan, Steven C Wallis, Julie M Varghese, Adrian Kark, Jeffrey Lipman, Jason A Roberts. Pharmacokinetics of Intraperitoneal Cefalothin and Cefazolin in Patients Being Treated for Peritoneal Dialysis-Associated Peritonitis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. 2016 Jul; 36(4):415-20. doi: 10.3747/pdi.2015.00008. [PMID: 26764340]
  • Suzanne L Parker, Yarmarly C Guerra Valero, Darren M Roberts, Jeffrey Lipman, Jason A Roberts, Steven C Wallis. Determination of Cefalothin and Cefazolin in Human Plasma, Urine and Peritoneal Dialysate by UHPLC-MS/MS: application to a pilot pharmacokinetic study in humans. Biomedical chromatography : BMC. 2016 Jun; 30(6):872-9. doi: 10.1002/bmc.3622. [PMID: 26394804]
  • Loreto Manosalva, Ana Mutis, Alejandro Urzúa, Victor Fajardo, Andrés Quiroz. Antibacterial Activity of Alkaloid Fractions from Berberis microphylla G. Forst and Study of Synergism with Ampicillin and Cephalothin. Molecules (Basel, Switzerland). 2016 Jan; 21(1):76. doi: 10.3390/molecules21010076. [PMID: 26760994]
  • André Pitondo-Silva, Gerson Nakazato, Juliana P Falcão, Kinue Irino, Roberto Martinez, Ana Lúcia C Darini, Rodrigo Tavanelli Hernandes. Phenotypic and genetic features of enteropathogenic Escherichia coli isolates from diarrheal children in the Ribeirão Preto metropolitan area, São Paulo State, Brazil. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 2015 Feb; 123(2):128-35. doi: 10.1111/apm.12314. [PMID: 25257819]
  • Isoken Henrietta Igbinosa. Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals. Tropical animal health and production. 2015 Jan; 47(1):37-43. doi: 10.1007/s11250-014-0680-8. [PMID: 25348646]
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  • Dongeun Yong, Mark A Toleman, Christian G Giske, Hyun S Cho, Kristina Sundman, Kyungwon Lee, Timothy R Walsh. Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrobial agents and chemotherapy. 2009 Dec; 53(12):5046-54. doi: 10.1128/aac.00774-09. [PMID: 19770275]
  • Andrew J Dalley, Renae Deans, Jeffrey Lipman, Bala Venkatesh, Michael Rudd, Michael S Roberts, Sheree E Cross. Unbound cephalothin pharmacokinetics in adult burn patients are related to the elapsed time after injury. Antimicrobial agents and chemotherapy. 2009 Dec; 53(12):5303-5. doi: 10.1128/aac.01600-08. [PMID: 19752272]
  • M José Figueras, Anabel Alperi, M José Saavedra, Wen-Chien Ko, Nieves Gonzalo, Maria Navarro, Antonio J Martínez-Murcia. Clinical relevance of the recently described species Aeromonas aquariorum. Journal of clinical microbiology. 2009 Nov; 47(11):3742-6. doi: 10.1128/jcm.02216-08. [PMID: 19741075]
  • Andrew J Dalley, Jeffrey Lipman, Renae Deans, Bala Venkatesh, Michael Rudd, Michael S Roberts, Sheree E Cross. Tissue accumulation of cephalothin in burns: a comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial agents and chemotherapy. 2009 Jan; 53(1):210-5. doi: 10.1128/aac.00718-08. [PMID: 18955521]
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  • Andrew J Dalley, Jeffrey Lipman, Bala Venkatesh, Michael Rudd, Michael S Roberts, Sheree E Cross. Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement. The Journal of antimicrobial chemotherapy. 2007 Jul; 60(1):166-9. doi: 10.1093/jac/dkm128. [PMID: 17504805]
  • S Carroll, M Hargreaves, A Goonetilleke. Sourcing faecal pollution from onsite wastewater treatment systems in surface waters using antibiotic resistance analysis. Journal of applied microbiology. 2005; 99(3):471-82. doi: 10.1111/j.1365-2672.2005.02644.x. [PMID: 16108788]
  • Ahmad H Al-Ghamdi, Mohammed A Al-Shadokhy, Abdulrahman A Al-Warthan. Electrochemical determination of Cephalothin antibiotic by adsorptive stripping voltammetric technique. Journal of pharmaceutical and biomedical analysis. 2004 Sep; 35(5):1001-9. doi: 10.1016/j.jpba.2004.02.034. [PMID: 15336347]
  • Sérgio A C Melo, Eduardo A R Castro, Antônio C Ponce-de-Leon, José A A Pereira. Use of selective media for detection of cephalothin-resistant bacteria in surgical patients. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. 2004 Jun; 8(3):190-6. doi: 10.1590/s1413-86702004000300001. [PMID: 15476050]
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  • Suparat Khamdang, Michio Takeda, Ellappan Babu, Rie Noshiro, Maristela Lika Onozato, Akihiro Tojo, Atsushi Enomoto, Xiu-Lin Huang, Shinichi Narikawa, Naohiko Anzai, Pawinee Piyachaturawat, Hitoshi Endou. Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. European journal of pharmacology. 2003 Mar; 465(1-2):1-7. doi: 10.1016/s0014-2999(03)01381-5. [PMID: 12650826]
  • Patricia A Arndt, George Garratty. Cross-reactivity of cefotetan and ceftriaxone antibodies, associated with hemolytic anemia, with other: cephalosporins and penicillin. American journal of clinical pathology. 2002 Aug; 118(2):256-62. doi: 10.1309/jfje-vukn-221t-g6ev. [PMID: 12162687]
  • Michio Takeda, Ellappan Babu, Shinichi Narikawa, Hitoshi Endou. Interaction of human organic anion transporters with various cephalosporin antibiotics. European journal of pharmacology. 2002 Mar; 438(3):137-42. doi: 10.1016/s0014-2999(02)01306-7. [PMID: 11909604]
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