Dexamethasone (BioDeep_00000014669)

 

Secondary id: BioDeep_00000016686

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one

化学式: C22H29FO5 (392.1998916)
中文名称: 地塞米松
谱图信息: 最多检出来源 Homo sapiens(COVID-19)(blood) 20%

分子结构信息

SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
InChI: InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

描述信息

Dexamethasone is only found in individuals that have used or taken this drug. It is an anti-inflammatory 9-fluoro-glucocorticoid. Dexamethasone is a glucocorticoid agonist. It is used for its antiinflammatory or immunosuppressive properties and ability to penetrate the CNS, dexamethasone is used alone to manage cerebral edema and with tobramycin to treat corticosteroid-responsive inflammatory ocular conditions. Dexamethasone can be used in the context of congenital adrenal hyperplasia, to prevent virilisation of a female fetus. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. This complex binds to DNA elements (glucocorticoid response elements) which results in a modification of transcription and, hence, protein synthesis in order to achieve inhibition of leukocyte infiltration at the site of inflammation, interference in the function of mediators of inflammatory response, suppression of humoral immune responses, and reduction in edema or scar tissue. The antiinflammatory actions of dexamethasone are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Dexamethasone has been shown to exhibit anesthetic, anti-microbial, appetite stimulant, muscle building and sedative functions (PMID 16571981, 19842390, 11563572, 20080405, 2898201). Its potency is about 20-30 times that of hydrocortisone and 4-5 times of prednisone.
H - Systemic hormonal preparations, excl. sex hormones and insulins > H02 - Corticosteroids for systemic use > H02A - Corticosteroids for systemic use, plain > H02AB - Glucocorticoids
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07X - Corticosteroids, other combinations > D07XB - Corticosteroids, moderately potent, other combinations
S - Sensory organs > S01 - Ophthalmologicals > S01C - Antiinflammatory agents and antiinfectives in combination > S01CB - Corticosteroids/antiinfectives/mydriatics in combination
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AB - Corticosteroids, moderately potent (group ii)
D - Dermatologicals > D10 - Anti-acne preparations > D10A - Anti-acne preparations for topical use > D10AA - Corticosteroids, combinations for treatment of acne
A - Alimentary tract and metabolism > A01 - Stomatological preparations > A01A - Stomatological preparations > A01AC - Corticosteroids for local oral treatment
C - Cardiovascular system > C05 - Vasoprotectives > C05A - Agents for treatment of hemorrhoids and anal fissures for topical use > C05AA - Corticosteroids
R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids
Glucocorticoid with potent antiinflammatory props. Not FDA approved for use in food-producing animals, but may be used illegally
S - Sensory organs > S03 - Ophthalmological and otological preparations > S03B - Corticosteroids > S03BA - Corticosteroids
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials, DrugBank, Guide to PHARMACOLOGY
S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BA - Corticosteroids, plain
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
S - Sensory organs > S02 - Otologicals > S02B - Corticosteroids > S02BA - Corticosteroids
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent
[Raw Data] CB196_Dexamethasone_pos_30eV_isCID-10eV_rep000005.txt
[Raw Data] CB196_Dexamethasone_pos_20eV_isCID-10eV_rep000005.txt
[Raw Data] CB196_Dexamethasone_pos_40eV_isCID-10eV_rep000005.txt
[Raw Data] CB196_Dexamethasone_pos_10eV_isCID-10eV_rep000005.txt
[Raw Data] CB196_Dexamethasone_pos_50eV_isCID-10eV_rep000005.txt
D005765 - Gastrointestinal Agents > D000932 - Antiemetics
D002491 - Central Nervous System Agents
D000893 - Anti-Inflammatory Agents
D000970 - Antineoplastic Agents
Same as: D00292
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

162 个代谢物同义名

(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one; 9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone; 1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone; 16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone; Neomycin and polymyxin b sulphates and dexamethasone; Neomycin and polymyxin b sulfates and dexamethasone; 9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione; 16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol; 16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol; 16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol; 1-Dehydro-16α-methyl-9α-fluorohydrocortisone; 1-Dehydro-16a-methyl-9a-fluorohydrocortisone; Delta1-9alpha-Fluoro-16alpha-methylcortisol; 9-alpha-Fluoro-16-alpha-methylprednisolone; 9alpha -Fluoro-16alpha -methylprednisolone; 16alpha -Methyl-9alpha -fluoroprednisolone; 16-alpha-Methyl-9-alpha-fluoroprednisolone; 9alpha-Fluoro-16alpha-methyl-prednisolone; 16alpha-Methyl-9alpha-fluoroprednisolone; 9alpha-Fluoro-16alpha-methylprednisolone; 16a-Methyl-9a-fluoro-1-dehydrocortisol; 16Α-methyl-9α-fluoro-1-dehydrocortisol; alpha -Fluoro-16-alpha -methylcortisol; 9a-Fluoro-16BETA-methylprednisolone; PMS Dexamethasone elixir 0.5mg/5ML; 9a-Fluoro-16a-methylprednisolone; 9Α-fluoro-16α-methylprednisolone; 9-Fluoro-16-methylprednisolone; Dexamethasone Sodium Phosphate; Merz brand 2 OF dexamethasone; Merz brand 1 OF dexamethasone; Tobramycin and dexamethasone; Alcon brand OF dexamethasone; Merck brand OF dexamethasone; Foy brand OF dexamethasone; ECR brand OF dexamethasone; Ak dex OPH otic soln 0.1\\%; ICN brand OF dexamethasone; Methylfluorprednisolone; Fluormethylprednisolone; Naquasone (veterinary); Dexamethasone intensol; Tresaderm (veterinary); Azimycin (veterinary); Dexamethasone Acetate; Dexamethasone alcohol; Sandoz dexamethasone; Dexamethasone-omega; Dexamethasone base; Azium (veterinary); PMS-Dexamethasone; PHL-Dexamethasone; Maxidex ont 0.1\\%; Apo-dexamethasone; Maxidex sus 0.1\\%; SK-Dexamethasone; Dexasone 0.75MG; Hexadrol elixir; Mediamethasone; Dexamethasonum; Dexasone 0.5MG; Prednisolone F; Dexa-cortidelt; Dexamethansone; Dexa-scheroson; Deltafluorene; Decaject l.a.; Prednisolon F; Anaflogistico; Dexamethazone; Dexa-cortisyl; Dexamethasone; Desamethasone; Dexa mamallet; Decaject-l.a.; Dexametasona; Dexametasone; Superprednol; Dexasone 4MG; Desametasone; Visumetazone; Pet derm III; Hexadecadrol; Mymethasone; DEXONE 0.75; Aeroseb-dex; Lokalison F; Gammacorten; Dexadeltone; Fortecortin; Cortisumman; Millicorten; Dexapolcort; Sunia sol D; Aphtasolon; Isopto-dex; Dexasporin; Turbinaire; Decacortin; Dexacortin; Dexacortal; DEXONE 0.5; DEXONE 1.5; Dectancyl; NSC 34521; Dergramin; Deseronil; Dexa-sine; Aeroseb-D; Dexafarma; Desameton; Dexinoral; Dexacidin; Dexinolon; Desadrene; Decaspray; Dexameth; Dexacort; Policort; Luxazone; Dextelan; Ocu-trol; Dexalona; Tobradex; Dekacort; Maxitrol; Decaject; Dexaprol; Decameth; Dexasone; Oradexon; Decasone; Decaderm; Loverine; Dinormon; DEXONE 4; Decadron; Spoloven; Hexadrol; Corsone; Auxiron; Decalix; Dexason; Maxidex; Mexidex; Decagel; Dexapos; Bisu DS; Dex-ide; Calonat; Prodex; HL-Dex; Dexone; Dexpak; Dezone; Corson; Azium; DEXA; DXMS; DEX; DXM



数据库引用编号

22 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Veronica Margarita Gutierrez-Noya, Leobardo Manuel Gómez-Oliván, José Manuel Orozco-Hernández, Karina Elisa Rosales-Pérez, Idalia Casas-Hinojosa, Gustavo Axel Elizalde-Velázquez, Sandra Gracía-Medina, Marcela Galar-Martínez, Luis Alberto Orozco-Hernández. Eco-endocrinological dynamics: Unraveling dexamethasone's influence on the interrenal axis in juvenile carp Cyprinus carpio. The Science of the total environment. 2024 Jun; 931(?):172947. doi: 10.1016/j.scitotenv.2024.172947. [PMID: 38703837]
  • Mengze Ding, Xiaohan Wei, Changshun Liu, Xiaomei Tan. Mahuang Fuzi Xixin decoction alleviates allergic rhinitis by inhibiting NLRP3/Caspase-1/GSDMD-N-mediated pyroptosis. Journal of ethnopharmacology. 2024 Jun; 327(?):118041. doi: 10.1016/j.jep.2024.118041. [PMID: 38479543]
  • Young In Kim, Hyunjung Lee, Min Jung Kim, Chang Hwa Jung, Young-Soo Kim, Jiyun Ahn. Identification of Peucedanum japonicum Thunb. extract components and their protective effects against dexamethasone-induced muscle atrophy. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jun; 128(?):155449. doi: 10.1016/j.phymed.2024.155449. [PMID: 38518644]
  • Xiaoqi Zhao, Hao Xiao, Xiaomin Li, Lu Zhu, Yu Peng, Huijun Chen, Liaobin Chen, Dan Xu, Hui Wang. Multi-organ developmental toxicity and its characteristics in fetal mice induced by dexamethasone at different doses, stages, and courses during pregnancy. Archives of toxicology. 2024 Jun; 98(6):1891-1908. doi: 10.1007/s00204-024-03707-4. [PMID: 38522057]
  • Xiaolei Zhou, Shiyin Xu, Zixuan Zhang, Mingmeng Tang, Zitong Meng, Zhao Peng, Yuxiao Liao, Xuefeng Yang, Andreas K Nüssler, Liegang Liu, Wei Yang. Gouqi-derived nanovesicles (GqDNVs) inhibited dexamethasone-induced muscle atrophy associating with AMPK/SIRT1/PGC1α signaling pathway. Journal of nanobiotechnology. 2024 May; 22(1):276. doi: 10.1186/s12951-024-02563-9. [PMID: 38778385]
  • Diana Belen Onofre-Camarena, Gustavo Axel Elizalde-Velázquez, Leobardo Manuel Gómez-Oliván, Sandra García-Medina, Marcela Galar-Martínez, José Roberto Jerónimo Juárez, Selene Elizabeth Herrera-Vázquez. Assessing the impact of COVID-19 era drug combinations on hepatic functionality: A thorough investigation in adult Danio rerio. Environmental pollution (Barking, Essex : 1987). 2024 May; 349(?):123997. doi: 10.1016/j.envpol.2024.123997. [PMID: 38636837]
  • Shikha Raina, Emely Hübner, Esther Samuel, Gregor Nagel, Hendrik Fuchs. DT-13 attenuates inflammation by inhibiting NLRP3-inflammasome related genes in RAW264.7 macrophages. Biochemical and biophysical research communications. 2024 May; 708(?):149763. doi: 10.1016/j.bbrc.2024.149763. [PMID: 38503169]
  • Zihong Wu, Xi Fu, Hailiang Jing, Wenbo Huang, Xueke Li, Chong Xiao, Zhuohong Li, Fengming You. Herbal medicine for the prevention of chemotherapy-induced nausea and vomiting in patients with advanced colorectal cancer: A prospective randomized controlled trial. Journal of ethnopharmacology. 2024 May; 325(?):117853. doi: 10.1016/j.jep.2024.117853. [PMID: 38341113]
  • Humaira Gul, Abida Hussain, Faraza Javaid, Kifayat Ullah Khan, Abdul Basit, Mosab Arafat, Fiza Hussain. Novel insights into the anti-asthmatic effect of Raphanus sativus L. (Raphani Semen): Targeting immune cells, inflammatory pathways and oxidative stress markers. Journal of ethnopharmacology. 2024 May; 325(?):117851. doi: 10.1016/j.jep.2024.117851. [PMID: 38336182]
  • Tiandan Li, Xiaochao Hu, Lingyang Fan, Yong Yang, Kai He. Myricanol improves metabolic profiles in dexamethasone induced lipid and protein metabolism disorders in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116557. doi: 10.1016/j.biopha.2024.116557. [PMID: 38583337]
  • Haixia Xiong, Peili Zhang, Dongcheng Wang, Zhimin Zhou, Jianjun Sun, Mingfang Diao. A silk-based hydrogel containing dexamethasone and lipoic acid microcrystals for local delivery to the inner ear. Colloids and surfaces. B, Biointerfaces. 2024 May; 237(?):113855. doi: 10.1016/j.colsurfb.2024.113855. [PMID: 38513298]
  • Javier Avilés-Prieto, Manuel Caro-Magdaleno, Enrique Rodríguez-de-la-Rúa-Franch. Peripheral Ulcerative Keratopathy following Systemic Treatment with Bortezomib: A Case Report. Ocular immunology and inflammation. 2024 May; 32(4):470-472. doi: 10.1080/09273948.2023.2173241. [PMID: 36780594]
  • Swen Bremer, Eva Weitkemper, Hanns Häberlein, Sebastian Franken. St. John's wort extract Ze 117 alters the membrane fluidity of C6 glioma cells by influencing cellular cholesterol metabolism. Scientific reports. 2024 04; 14(1):9878. doi: 10.1038/s41598-024-60562-0. [PMID: 38684848]
  • Xianwen Xiao, Yuan Lin, Xie Fang, Zhiwen Xie, Shunrong Luo, Huping Wu. Clinical features and comprehensive treatment of persistent corneal epithelial dysfunction after cataract surgery. BMC ophthalmology. 2024 Apr; 24(1):197. doi: 10.1186/s12886-024-03466-x. [PMID: 38671418]
  • Ngoc Bao Nguyen, Tam Thi Le, Suk Woo Kang, Kwang Hyun Cha, Sowoon Choi, Hye-Young Youn, Sang Hoon Jung, Myungsuk Kim. Cornflower Extract and Its Active Components Alleviate Dexamethasone-Induced Muscle Wasting by Targeting Cannabinoid Receptors and Modulating Gut Microbiota. Nutrients. 2024 Apr; 16(8):. doi: 10.3390/nu16081130. [PMID: 38674820]
  • Hee Won Seo, Seok Hwa Ko, Jae Ho Chung, Hayoung Byun, Jeong-Hun Shin, Seung Hwan Lee. A prognostic value of estimated pulse wave velocity in idiopathic sudden sensorineural hearing loss. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 2024 Apr; 281(4):1745-1751. doi: 10.1007/s00405-023-08289-y. [PMID: 37898594]
  • Lina Jiao, Haiyan Jin, Zuchen Song, Zheng Wang, Lin Yu, Ruihong Yu, Deyun Wang, Qian Gao, Song Peng, Haifeng Sun, Tao Zhang, Xue Fei Wang, Zhenguang Liu. The effect of lentinan on dexamethasone-induced immunosuppression in mice. International journal of biological macromolecules. 2024 Apr; 264(Pt 2):130621. doi: 10.1016/j.ijbiomac.2024.130621. [PMID: 38447834]
  • L L Liang, S Ju, Z H Cui. [Dislocation into the anterior chamber and spontaneous repositioning of a dexamethasone intravitreal implant: a case report]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology. 2024 Mar; 60(3):272-274. doi: 10.3760/cma.j.cn112142-20231025-00181. [PMID: 38462376]
  • Yinglan Yu, Mingjie Ni, Yaxian Zheng, Yuan Huang. Airway epithelial-targeted nanoparticle reverses asthma in inhalation therapy. Journal of controlled release : official journal of the Controlled Release Society. 2024 Mar; 367(?):223-234. doi: 10.1016/j.jconrel.2024.01.044. [PMID: 38272396]
  • Jongbeom Chae, Dongyup Hahn, Ju-Ock Nam. Macamide, a component of maca (Lepidium meyenii Walp) lipophilic extract, enhances myogenic differentiation via AKT/p38 signaling and attenuates dexamethasone-induced muscle atrophy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Mar; 172(?):116249. doi: 10.1016/j.biopha.2024.116249. [PMID: 38340399]
  • Xinglong Zhang, Zhenhuan Yang, Qian Xu, Chunlei Xu, Wei Shi, Ran Pang, Kai Zhang, Xinyu Liang, Hui Li, Zhijun Li, Huafeng Zhang. Dexamethasone Induced Osteocyte Apoptosis in Steroid-Induced Femoral Head Osteonecrosis through ROS-Mediated Oxidative Stress. Orthopaedic surgery. 2024 Mar; 16(3):733-744. doi: 10.1111/os.14010. [PMID: 38384174]
  • Fatemeh Amin, Arghavan Memarzia, Hamideh Kazemi Rad, Hamid Reza Kazerani, Seyedeh Zahra Ghasemi, Mohammad Hossein Boskabady. Inhaled paraquat-induced lung injury in rat, improved by the extract of Zataria multiflora boiss and PPARγ agonist, pioglitazone. Legal medicine (Tokyo, Japan). 2024 Mar; 67(?):102335. doi: 10.1016/j.legalmed.2023.102335. [PMID: 37951808]
  • Qianshuang Geng, Jie Li, Xi Li, Wenjie Zhang, Guoxiang Zhang, Li Ge, Li Liang. A case report: Nonsecretory multiple myeloma presenting with bone pain. Medicine. 2024 Feb; 103(5):e36951. doi: 10.1097/md.0000000000036951. [PMID: 38306571]
  • Mehdi Salari, Ahmad Alahabadi, Abolfazl Rahmani-Sani, Mohammad Miri, Mohsen Yazdani-Aval, Hadi Lotfi, Mohammad Hossien Saghi, Ayoob Rastegar, Mohammad Noori Sepehr, Mohammad Darvishmotevalli. A comparative study of response surface methodology and artificial neural network based algorithm genetic for modeling and optimization of EP/US/GAC oxidation process in dexamethasone degradation: Application for real wastewater, electrical energy consumption. Chemosphere. 2024 Feb; 349(?):140832. doi: 10.1016/j.chemosphere.2023.140832. [PMID: 38042425]
  • Lingchao Miao, Xutao Zhang, Haolin Zhang, Meng Sam Cheong, Xiaojia Chen, Mohamed A Farag, Wai San Cheang, Jianbo Xiao. Baicalin ameliorates insulin resistance and regulates hepatic glucose metabolism via activating insulin signaling pathway in obese pre-diabetic mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Feb; 124(?):155296. doi: 10.1016/j.phymed.2023.155296. [PMID: 38176276]
  • Yu Ran, Shanmei Yin, Pei Xie, Yaxue Liu, Ying Wang, Zongning Yin. ICAM-1 targeted and ROS-responsive nanoparticles for the treatment of acute lung injury. Nanoscale. 2024 Jan; 16(4):1983-1998. doi: 10.1039/d3nr04401g. [PMID: 38189459]
  • Jie Ai, Yinhua Weng, Liyan Jiang, Chao Liu, Hongbo Liu, Huoying Chen. Dexamethasone Suppresses IL-33-exacerbated Malignant Phenotype of U87MG Glioblastoma Cells via NF-κB and MAPK Signaling Pathways. Anti-cancer agents in medicinal chemistry. 2024; 24(5):389-397. doi: 10.2174/0118715206281991231222073858. [PMID: 38192141]
  • Ahmed E Amer, Hamdy A Ghoneim, Rania R Abdelaziz, George S G Shehatou, Ghada M Suddek. Saroglitazar mitigated NASH-associated hepatic injury in dexamethasone-treated rats via modulating autophagy, apoptosis, and necroptosis. Toxicology and applied pharmacology. 2024 01; 482(?):116774. doi: 10.1016/j.taap.2023.116774. [PMID: 38040297]
  • Kai Dong, Ying Zhang, Hong Rui Ji, Ze Lin Guan, Dan Yang Wang, Zi Yang Guo, Shu Jing Deng, Bin Yang He, Jian Feng Xing, Cui Yu You. Dexamethasone-Loaded Lipid Calcium Phosphate Nanoparticles Treat Experimental Colitis by Regulating Macrophage Polarization in Inflammatory Sites. International journal of nanomedicine. 2024; 19(?):993-1016. doi: 10.2147/ijn.s442369. [PMID: 38299194]
  • Ruihu Du, Xiaoqi Zhao, Ling Song, Hui Wang, Dongyang Liu, Qi Wang. A physiologically based toxicokinetic model of P-glycoprotein transporter-mediated placenta perfusion of dexamethasone in the pregnant rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2024 Jan; 183(?):114213. doi: 10.1016/j.fct.2023.114213. [PMID: 38052401]
  • Mi-Jeong Lee, Vishwajeet Puri, Susan K Fried. Metabolic and structural remodeling during browning of primary human adipocytes derived from omental and subcutaneous depots. Obesity (Silver Spring, Md.). 2024 Jan; 32(1):70-79. doi: 10.1002/oby.23912. [PMID: 37929774]
  • Rebecca Riedl, Annika Kühn, Yvonne Hupfer, Betty Hebecker, Lukas K Peltner, Paul M Jordan, Oliver Werz, Stefan Lorkowski, Cornelia Wiegand, Maria Wallert. Characterization of Different Inflammatory Skin Conditions in a Mouse Model of DNCB-Induced Atopic Dermatitis. Inflammation. 2023 Dec; ?(?):. doi: 10.1007/s10753-023-01943-x. [PMID: 38150167]
  • Haimin Chen, Haiqi Chen, Yan Zhou, Weiwei Xu, Jingjing Yu, Yao Xu, Fan Zhou. Comparative efficacy of novel-drugs combined therapeutic regimens on relapsed/refractory multiple myeloma: a network meta-analysis. Hematology (Amsterdam, Netherlands). 2023 Dec; 28(1):2225342. doi: 10.1080/16078454.2023.2225342. [PMID: 37343159]
  • Yifan Liu, Kaimin Wu, Yinkun Fu, Wenyan Li, Xu-Yun Zhao. Slc7a11 stimulates glutathione synthesis to preserve fatty acid metabolism in primary hepatocytes. Redox report : communications in free radical research. 2023 Dec; 28(1):2260646. doi: 10.1080/13510002.2023.2260646. [PMID: 37750478]
  • Juan C Durán-Álvarez, Blanca Prado, Rodolfo Zanella, Mario Rodríguez, Suhaila Díaz. Wastewater surveillance of pharmaceuticals during the COVID-19 pandemic in Mexico City and the Mezquital Valley: A comprehensive environmental risk assessment. The Science of the total environment. 2023 Nov; 900(?):165886. doi: 10.1016/j.scitotenv.2023.165886. [PMID: 37524191]
  • Yumeng Zhang, Wenhan Lu, Xiaoxue Li, Yu Wang, Lin Li, Yifan Dai, Haiyuan Yang, Ying Wang. Mfat-1 ameliorates cachexia after hypoxic-ischemic brain damage in mice by protecting the hypothalamus-pituitary-adrenal axis. Life sciences. 2023 Nov; 333(?):122172. doi: 10.1016/j.lfs.2023.122172. [PMID: 37832632]
  • Veronica Margarita Gutiérrez-Noya, Leobardo Manuel Gómez-Oliván, Idalia Casas-Hinojosa, Sandra García-Medina, Karina Elisa Rosales-Pérez, José Manuel Orozco-Hernández, Gustavo Axel Elizalde-Velázquez, Marcela Galar-Martínez, Octavio Dublán-García, Hariz Islas-Flores. Short-term exposure to dexamethasone at environmentally relevant concentrations impairs embryonic development in Cyprinus carpio: Bioconcentration and alteration of oxidative stress-related gene expression patterns. The Science of the total environment. 2023 Nov; 898(?):165528. doi: 10.1016/j.scitotenv.2023.165528. [PMID: 37451451]
  • Hongfeng Ruan, Huihao Zhang, Jing Feng, Huan Luo, Fangda Fu, Sai Yao, Chengcong Zhou, Zhiguo Zhang, Yishan Bian, Hongting Jin, Yuliang Zhang, Chengliang Wu, Peijian Tong. Inhibition of Caspase-1-mediated pyroptosis promotes osteogenic differentiation, offering a therapeutic target for osteoporosis. International immunopharmacology. 2023 Nov; 124(Pt B):110901. doi: 10.1016/j.intimp.2023.110901. [PMID: 37839278]
  • Arghavan Memarzia, Seyedeh Zahra Ghasemi, Sepideh Behrouz, Mohammad Hossein Boskabady. The effects of Crocus sativus extract on inhaled paraquat-induced lung inflammation, oxidative stress, pathological changes and tracheal responsiveness in rats. Toxicon : official journal of the International Society on Toxinology. 2023 Oct; ?(?):107316. doi: 10.1016/j.toxicon.2023.107316. [PMID: 37827264]
  • Tomoaki Ishida, Kei Kawada, Kohei Jobu, Shumpei Morisawa, Tetsushi Kawazoe, Satomi Nishimura, Keita Akagaki, Saburo Yoshioka, Mitsuhiko Miyamura. Exosome-like nanoparticles derived from Allium tuberosum prevent neuroinflammation in microglia-like cells. The Journal of pharmacy and pharmacology. 2023 Oct; 75(10):1322-1331. doi: 10.1093/jpp/rgad062. [PMID: 37390476]
  • Muhammad Usman Ali Khan, Tasleem Akhtar, Nadia Naseem, Usman Aftab, Safdar Hussain, Muhammad Shahzad. Evaluation of therapeutic potential of ivermectin against complete Freund's adjuvant-induced arthritis in rats: Involvement of inflammatory mediators. Fundamental & clinical pharmacology. 2023 Oct; 37(5):971-982. doi: 10.1111/fcp.12902. [PMID: 37085956]
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  • Xinglong Zhang, Ran Pang, Kai Zhang, Qian Xu, Chunlei Xu, Wei Shi, Xinyu Liang, Dong Li, Wenhao Cui, Shucai Bai, Zhijun Li, Hui Li, Huafeng Zhang. Apocynin exerts cytoprotective effects on dexamethasone-induced osteoblasts by inhibiting oxidative stress through the Nrf2 signalling pathway. Journal of cellular and molecular medicine. 2023 Sep; ?(?):. doi: 10.1111/jcmm.17974. [PMID: 37749949]
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  • Prerna Dogra, Lana Šambula, Jasmine Saini, Karthik Thangamuthu, Shobana Athimulam, Danae A Delivanis, Dimitra A Baikousi, Rohit Nathani, Catherine D Zhang, Natalia Genere, Zara Salman, Adina F Turcu, Urszula Ambroziak, Raul G Garcia, Sara J Achenbach, Elizabeth J Atkinson, Sumitabh Singh, Nathan K LeBrasseur, Darko Kastelan, Irina Bancos. High prevalence of frailty in patients with adrenal adenomas and adrenocortical hormone excess: a cross-sectional multi-centre study with prospective enrolment. European journal of endocrinology. 2023 Sep; 189(3):318-326. doi: 10.1093/ejendo/lvad113. [PMID: 37590964]
  • Min Zeng, Junxiang Li, Tingting Zheng, Xi Yan, Feng Yuan, Bingbing Xiang. Electropress Needle Stimulation for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Sleeve Gastrectomy: A Prospective, Randomized Controlled Trial. Obesity surgery. 2023 09; 33(9):2831-2840. doi: 10.1007/s11695-023-06752-7. [PMID: 37507634]
  • Zhigang Rao, Elena Brunner, Benjamin Giszas, Aishwarya Iyer-Bierhoff, Jana Gerstmeier, Friedemann Börner, Paul M Jordan, Simona Pace, Katharina P L Meyer, Robert K Hofstetter, Daniel Merk, Christian Paulenz, Thorsten Heinzel, Philip C Grunert, Andreas Stallmach, Charles N Serhan, Markus Werner, Oliver Werz. Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution. Proceedings of the National Academy of Sciences of the United States of America. 2023 Aug; 120(35):e2302070120. doi: 10.1073/pnas.2302070120. [PMID: 37603745]
  • Sonu Ambwani, Rigzin Dolma, Raunak Sharma, Amandip Kaur, Himani Singh, Anamitra Ruj, Tanuj Kumar Ambwani. Modulation of inflammatory and oxidative stress biomarkers due to dexamethasone exposure in chicken splenocytes. Veterinary immunology and immunopathology. 2023 Jul; 262(?):110632. doi: 10.1016/j.vetimm.2023.110632. [PMID: 37517103]
  • Yongyan Zhang, Ying Li, Feng Ji, Keqin Zhang, Yi Lou, Hua Xu. Transcutaneous electrical acupoint stimulation versus dexamethasone for prophylaxis of postoperative nausea and vomiting in breast surgery: A non-inferiority randomized controlled trial. Surgery. 2023 Jul; ?(?):. doi: 10.1016/j.surg.2023.06.014. [PMID: 37482441]
  • Yingjie Qiao, Yanhong Yang, Jianmin Wang, Muzhen Li, Lijun Zheng, Huadong Li, Shidong Zhang. Tuina in a Frozen Shoulder Rat Model: An Efficient and Reproducible Protocol. Journal of visualized experiments : JoVE. 2023 07; ?(197):. doi: 10.3791/65440. [PMID: 37638776]
  • Wenjie Chai, Shaopeng Wang, Donghang Zhang. Optimal dose of perineural dexamethasone for the prolongation of analgesia for peripheral nerve blocks: protocol for a systematic review and meta-analysis. BMJ open. 2023 07; 13(7):e072598. doi: 10.1136/bmjopen-2023-072598. [PMID: 37474174]
  • Wangkuk Son, Katie Brown, Aaron Persinger, Ashley Pryke, Jason Lin, Zereque Powell, Noah Wallace, Marie van der Merwe, Melissa Puppa. Effect of Omega-3 Rich High-Fat Diet on Markers of Tissue Lipid Metabolism in Glucocorticoid-Treated Mice. International journal of molecular sciences. 2023 Jul; 24(14):. doi: 10.3390/ijms241411492. [PMID: 37511252]
  • Luana Laura Sales da Silva, Jéssica Anastácia Silva Barbosa, Juliana Morelli Lopes Gonçalves João, Silvia Fukuzaki, Leandro do Nascimento Camargo, Tabata Maruyama Dos Santos, Elaine Cristina de Campos, Arthur Silva Costa, Beatriz Mangueira Saraiva-Romanholo, Suellen Karoline Moreira Bezerra, Fernanda Tenório Quirino Dos Santos Lopes, Camila Ramalho Bonturi, Maria Luiza Vilela Oliva, Edna Aparecida Leick, Renato Fraga Righetti, Iolanda de Fátima Lopes Calvo Tibério. Effects of a Peptide Derived from the Primary Sequence of a Kallikrein Inhibitor Isolated from Bauhinia bauhinioides (pep-BbKI) in an Asthma-COPD Overlap (ACO) Model. International journal of molecular sciences. 2023 Jul; 24(14):. doi: 10.3390/ijms241411261. [PMID: 37511021]
  • Mujeeb Ur-Rehman, Franceline Reynaud, Sinda Lepetre, Sonia Abreu, Pierre Chaminade, Elias Fattal, Nicolas Tsapis. Modulation of release and pharmacokinetics from nanoscale lipid prodrugs of dexamethasone with variable linkage chemistry. Journal of controlled release : official journal of the Controlled Release Society. 2023 Jul; 360(?):293-303. doi: 10.1016/j.jconrel.2023.06.031. [PMID: 37391032]
  • Alexander Rysin, Wouter J M Lokerse, Michael Paal, Katharina Habler, Barbara Wedmann, Martin Hossann, Gerhard Winter, Lars H Lindner. Heat-Triggered Release of Dexamethasone from Thermosensitive Liposomes Using Prodrugs or Excipients. Journal of pharmaceutical sciences. 2023 07; 112(7):1947-1956. doi: 10.1016/j.xphs.2023.04.001. [PMID: 37030437]
  • Duosheng Luo, Yaru Zhao, Zhaoyan Fang, Yating Zhao, Yi Han, Jingyu Piao, Xianglu Rong, Jiao Guo. Tianhuang formula regulates adipocyte mitochondrial function by AMPK/MICU1 pathway in HFD/STZ-induced T2DM mice. BMC complementary medicine and therapies. 2023 Jun; 23(1):202. doi: 10.1186/s12906-023-04009-5. [PMID: 37337224]
  • Elvis Ticiani, Yong Pu, Madison White, Victoria Adomshick, Almudena Veiga-Lopez. Organotin mixtures reveal interactions that modulate adipogenic differentiation in 3T3-L1 preadipocytes. Archives of toxicology. 2023 06; 97(6):1649-1658. doi: 10.1007/s00204-023-03512-5. [PMID: 37142754]
  • Kamila Bohne Japiassu, Francois Fay, Alessandro Marengo, Sebastião A Mendanha, Catherine Cailleau, Younès Louaguenouni, Qinglin Wang, Stéphanie Denis, Nicolas Tsapis, Thais Leite Nascimento, Eliana Martins Lima, Elias Fattal. Hyaluronic acid-conjugated liposomes loaded with dexamethasone: A promising approach for the treatment of inflammatory diseases. International journal of pharmaceutics. 2023 May; 639(?):122946. doi: 10.1016/j.ijpharm.2023.122946. [PMID: 37044230]
  • Cuicui Wang, In-Jeong Kim, Hye-Rim Seong, Chan Ho Noh, Sangryong Park, Tae Myoung Kim, Heon Sang Jeong, Ka Young Kim, Seung Tae Kim, Hyun-Gyun Yuk, Sang-Chul Kwon, Ehn-Kyoung Choi, Yun-Bae Kim. Antioxidative and Anti-Inflammatory Activities of Rosebud Extracts of Newly Crossbred Roses. Nutrients. 2023 May; 15(10):. doi: 10.3390/nu15102376. [PMID: 37242259]
  • Ritasha Sawoo, Rajen Dey, Rituparna Ghosh, Biswadev Bishayi. Exogenous IL-10 posttreatment along with TLR4 and TNFR1 blockade improves tissue antioxidant status by modulating sepsis-induced macrophage polarization. Journal of applied toxicology : JAT. 2023 May; ?(?):. doi: 10.1002/jat.4496. [PMID: 37177863]
  • Yuting Long, Han Wang, Zitong Ma, Yuman Li, Zaina Ma, Ping Yu, Xiufeng Tang, Renhui Liu. Combined Epimedii Folium and Ligustri Lucidi Fructus with dexamethasone alleviate the proliferation of airway smooth muscle cells by regulating apoptosis/autophagy. Journal of ethnopharmacology. 2023 May; 314(?):116547. doi: 10.1016/j.jep.2023.116547. [PMID: 37178983]
  • Mohammad Amin Rajizadeh, Mohammad Abbas Bejeshk, Amir Hossein Doustimotlagh, Hamid Najafipour, Maryam Eftekhari, Merat Mahmoodi, Mahdokht Azizi, Fahimeh Rostamabadi, Hossein Pourghadamyari. The Alleviating Impacts of Quercetin on Inflammation and Oxidant-antioxidant Imbalance in Rats with Allergic Asthma. Iranian journal of allergy, asthma, and immunology. 2023 Apr; 22(2):138-149. doi: 10.18502/ijaai.v22i2.12675. [PMID: 37496407]
  • Kei Kawada, Tomoaki Ishida, Kohei Jobu, Shumpei Morisawa, Motoki Nishida, Naohisa Tamura, Saburo Yoshioka, Mitsuhiko Miyamura. Glycyrrhizae Radix suppresses lipopolysaccharide- and diazepam-induced nerve inflammation in the hippocampus, and contracts the duration of pentobarbital- induced loss of righting reflex in a mouse model. Journal of natural medicines. 2023 Apr; ?(?):. doi: 10.1007/s11418-023-01700-2. [PMID: 37115471]
  • Mona F Mahmoud, Nora Tawfeek, Noura Ali, Rehab A Hasan, Mansour Sobeh, Assem M El-Shazly. Salix babylonica L. mitigates pancreatic damage by regulating the Beclin-P62/SQSTM1 autophagy pathway in rats. Journal of ethnopharmacology. 2023 Apr; ?(?):116425. doi: 10.1016/j.jep.2023.116425. [PMID: 37031826]
  • Ye Liu, Rema Naskar, Sabin Acharya, Le Ba Vinh, Jin Hyeok Kim, Jae-Young Lee, Young Ho Kim, Jong Seong Kang, Inkyu Hwang. Inotodiol, an antiasthmatic agent with efficacy and safety, preferentially impairs membrane-proximal signaling for mast cell activation. International immunopharmacology. 2023 Apr; 117(?):109854. doi: 10.1016/j.intimp.2023.109854. [PMID: 36812673]
  • Flávia Natividade da Silva, Priscila Laiz Zimath, Thais Alves do Amaral, José Rodrigo Nascimento Martins, Alex Rafacho. Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats. Life sciences. 2023 Apr; 322(?):121660. doi: 10.1016/j.lfs.2023.121660. [PMID: 37011876]
  • Mizuki Doi, Hiroki Tanaka, Takara Ohoto, Naoya Miura, Yu Sakurai, Hiroto Hatakeyama, Hidetaka Akita. Reactivation of Anticancer Immunity by Resetting Interorgan Crosstalk in Immune-Suppressive Cells with a Nanoparticulated Anti-Inflammatory Drug. Small (Weinheim an der Bergstrasse, Germany). 2023 04; 19(16):e2205131. doi: 10.1002/smll.202205131. [PMID: 36703512]
  • Wang Wang, Yang Liu, Liangliang Xiong, Dejuan Sun, Hui Wang, Zhuorui Song, Yutong Li, Hua Li, Lixia Chen. Synthesis of Lathyrol PROTACs and Evaluation of Their Anti-Inflammatory Activities. Journal of natural products. 2023 Mar; ?(?):. doi: 10.1021/acs.jnatprod.2c00912. [PMID: 37002536]
  • Xuemei Liu, Yan Yu, Yanqing Wu, Ai Luo, Mei Yang, Ting Li, Tingqian Li, Bing Mao, Xiaoting Chen, Juanjuan Fu, Hongli Jiang, Wei Liu. A systematic pharmacology-based in vivo study to reveal the effective mechanism of Yupingfeng in asthma treatment. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Mar; 114(?):154783. doi: 10.1016/j.phymed.2023.154783. [PMID: 37004399]
  • Mi Huang, Lei Yu, Ying Wang, Chunlin Yang. Epimedin C protects dexamethasone-induced osteoblasts through NRF1/RhoA pathway. Aging. 2023 03; 15(6):2033-2045. doi: 10.18632/aging.204588. [PMID: 36920182]
  • Hassan Rakhshandeh, Vafa Baradaran Rahimi, Bahman Dehghan-Naieri, Pouria Rahmanian-Devin, Ali Jebalbarezy, Maede Hasanpour, Mehrdad Iranshahi, Vahid Reza Askari. Peritoneal lavage with Glycyrrhiza glabra is effective in preventing peritoneal adhesion in a rat model. Inflammopharmacology. 2023 Mar; ?(?):. doi: 10.1007/s10787-023-01139-7. [PMID: 36862226]
  • Shu-Min Lin, Chung-Shu Lee, Allen Chung-Cheng Huang, Tzu-Hsuan Chiu, Ko-Wei Chang, Tse-Hung Huang, Tsung-Hsien Yang, Yi-Hsien Shiao, Fu-Tsai Chung, Chyi-Liang Chen, Cheng-Hsun Chiu. Effects of dexamethasone use on viral clearance among patients with COVID-19: a multicenter cohort study. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2023 Mar; 128(?):257-264. doi: 10.1016/j.ijid.2023.01.011. [PMID: 36642207]
  • He Li, Kaifang Guan, Min Liu, Dandan Liu, Wenqiong Wang, Aihua Zhu. Novel antioxidant peptides from MFGM protein Hydrolysates: Separation, identification and effects on Dexamethasone-induced mitochondrial dysfunction. Food chemistry. 2023 Mar; 403(?):134473. doi: 10.1016/j.foodchem.2022.134473. [PMID: 36358083]
  • Bhupinder Kaur, Nitish Kumar, Manoj K Patel, Kanwaljit Chopra, Shweta Saxena. Validation of traditional claims of anti-arthritic efficacy of trans-Himalayan snow mountain garlic (Allium ampeloprasum L.) extract using adjuvant-induced arthritis rat model: A comparative evaluation with normal garlic (Allium sativum L.) and dexamethasone. Journal of ethnopharmacology. 2023 Mar; 303(?):115939. doi: 10.1016/j.jep.2022.115939. [PMID: 36435406]
  • Michelle C Maier, Scott Nankervis, Morgan E Wallace, Tamekha Develyn, Mark A Myers. Dexamethasone leads to Zn2+ accumulation and increased unbound Zn2+ in C2C12 muscle and 3T3-L1 adipose cells. Journal of cellular biochemistry. 2023 03; 124(3):409-420. doi: 10.1002/jcb.30376. [PMID: 36716229]
  • Ahmed Nadeem, Samiyah Alshehri, Naif O Al-Harbi, Sheikh F Ahmad, Norah A Albekairi, Saleh A Alqarni, Khaild E Ibrahim, Ali S Alfardan, Ali A Alshamrani, Sami B Bin Salman, Sabry M Attia. Bruton's tyrosine kinase inhibition suppresses neutrophilic inflammation and restores histone deacetylase 2 expression in myeloid and structural cells in a mixed granulocytic mouse model of asthma. International immunopharmacology. 2023 Feb; 117(?):109920. doi: 10.1016/j.intimp.2023.109920. [PMID: 36827920]
  • Bin Jia, Yaping Jiang, Yao Yao, Yingxing Xu, Yingzhen Wang, Tao Li. Baicalin attenuates dexamethasone-induced apoptosis of bone marrow mesenchymal stem cells by activating the hedgehog signaling pathway. Chinese medical journal. 2023 Feb; ?(?):. doi: 10.1097/cm9.0000000000002113. [PMID: 36804262]
  • Fernanda Rodrigues Santana, Marília Trindade de Santana Souza, Enilton Aparecido Camargo, James Almada da Silva. Anti-inflammatory and antinociceptive effects of a pectinolide-enriched fraction from Mesosphaerum pectinatum (L.) Kuntze. Journal of ethnopharmacology. 2023 Feb; 302(Pt B):115916. doi: 10.1016/j.jep.2022.115916. [PMID: 36379417]
  • Annamaria Di Turi, Marina Antonacci, Jacopo Raffaele Dibenedetto, Fatima Maqoud, Francesco Leonetti, Gerardo Centoducati, Nicola Colonna, Domenico Tricarico. Molecular Composition and Biological Activity of a Novel Acetonitrile-Water Extract of Lens Culinaris Medik in Murine Native Cells and Cell Lines Exposed to Different Chemotherapeutics Using Mass Spectrometry. Cells. 2023 Feb; 12(4):. doi: 10.3390/cells12040575. [PMID: 36831242]
  • Junjie Yue, Caiting Sun, Jinyuan Tang, Qiyuan Zhang, Mengjie Lou, Hongwen Sun, Lianying Zhang. Downregulation of miRNA-155-5p contributes to the adipogenic activity of 2-ethylhexyl diphenyl phosphate in 3T3-L1 preadipocytes. Toxicology. 2023 Feb; 487(?):153452. doi: 10.1016/j.tox.2023.153452. [PMID: 36764644]
  • Eunji Park, Hojung Choi, Cao-Sang Truong, Hee-Sook Jun. The Inhibition of Autophagy and Pyroptosis by an Ethanol Extract of Nelumbo nucifera Leaf Contributes to the Amelioration of Dexamethasone-Induced Muscle Atrophy. Nutrients. 2023 Feb; 15(4):. doi: 10.3390/nu15040804. [PMID: 36839161]
  • Natália de Matos Balsalobre, Elisangela Dos Santos, Sidney Mariano Dos Santos, Arielle Cristina Arena, Elisabete Castelon Konkiewitz, Edward Benjamin Ziff, Anelise Samara Nazari Formagio, Candida Aparecida Leite Kassuya. Potential anti-arthritic and analgesic properties of essential oil and viridiflorol obtained from Allophylus edulis leaves in mice. Journal of ethnopharmacology. 2023 Jan; 301(?):115785. doi: 10.1016/j.jep.2022.115785. [PMID: 36223847]
  • Juan Lv, Guozhong Xue, Yunxia Zhang, Xinbin Wang, Enlai Dai. Icariin synergizes therapeutic effect of dexamethasone on adriamycin-induced nephrotic syndrome. European journal of medical research. 2023 Jan; 28(1):52. doi: 10.1186/s40001-022-00973-9. [PMID: 36707848]
  • Mahmut Kaya, Ferdane Atas, Nilufer Kocak, Taylan Ozturk, Ziya Ayhan, Suleyman Kaynak. Intravitreal Ranibizumab and Dexamethasone Implant Injections as Primary Treatment of Diabetic Macular Edema: The Month 24 Results from Simultaneously Double Protocol. Current eye research. 2023 Jan; ?(?):1-8. doi: 10.1080/02713683.2023.2168013. [PMID: 36629472]
  • Khalid Bashir Dar, Ruhban Ansar Parry, Aashiq Hussain Bhat, Afaq Hameed Beigh, Maroof Ahmed, Umer Majeed Khaja, Aijaz Hassan Ganie, Manzoor Ahmad Mir, Bilal Ahmad Reshi, Ishfaq Shafi Khan, Showkat Ahmad Ganie. Immunomodulatory efficacy of Cousinia thomsonii C.B. Clarke in ameliorating inflammatory cascade expressions. Journal of ethnopharmacology. 2023 Jan; 300(?):115727. doi: 10.1016/j.jep.2022.115727. [PMID: 36116611]
  • Yixuan Wang, Jian Gao, Ying Yu, Lin Zhou, Miao Wang, Wenwen Xue, Bo Liu, Xudong Wu, Xuefeng Wu, Huiyuan Gao, Yan Shen, Qiang Xu. A plant-derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy. British journal of pharmacology. 2023 01; 180(2):194-213. doi: 10.1111/bph.15957. [PMID: 36165414]
  • Wei Zhang, Hanna Nowotny, Marily Theodoropoulou, Julia Simon, Charlotte M Hemmer, Martin Bidlingmaier, Matthias K Auer, Martin Reincke, Henriette Uhlenhaut, Nicole Reisch. E47 as a novel glucocorticoid-dependent gene mediating lipid metabolism in patients with endogenous glucocorticoid excess. Frontiers in endocrinology. 2023; 14(?):1249863. doi: 10.3389/fendo.2023.1249863. [PMID: 38047107]
  • Agus Joko Susanto, Bambang Purwanto, Ambar Mudigdo, Brian Wasita. Lacrimal Gland Histopathology and Secretory Function in Sjögren's Syndrome Mice Model Treated with Moringa oleifera Lam. Leaf Extract. Anti-inflammatory & anti-allergy agents in medicinal chemistry. 2023; 21(3):166-172. doi: 10.2174/1871523022666221026145110. [PMID: 36305140]
  • Xin Ye, Yi-Feng Ren, Yu-Cheng Hu, Shi-Yan Tan, Hua Jiang, Long-Fei Zhang, Wei Shi, Yu-Ting Wang. Dexamethasone Does Not Provide Additional Clinical Analgesia Effect to Local Wound Infiltration: A Comprehensive Systematic Review and Meta-Analysis. Advances in wound care. 2023 01; 12(1):1-14. doi: 10.1089/wound.2021.0163. [PMID: 35081741]
  • Wenxiao Qiao, Lihong Meng, Ye Zhang, Dian Li, Jingjing Chen, Jinyun Wang, Di Xie, Xiaoming Xue. Safety and efficacy of glucocorticoids in the treatment of COVID-19: A meta-analysis of randomized control trials. Expert review of respiratory medicine. 2023 01; 17(1):81-96. doi: 10.1080/17476348.2023.2177155. [PMID: 36738136]
  • Chang Huang, Zhutian Zhang, Jifeng Gu, Dan Li, Shunxiang Gao, Rong Zhang, Rong Shi, Jianguo Sun. Combined Therapy of Experimental Autoimmune Uveitis by a Dual-Drug Nanocomposite Formulation with Berberine and Dexamethasone. International journal of nanomedicine. 2023; 18(?):4347-4363. doi: 10.2147/ijn.s417750. [PMID: 37545873]
  • Svetlana Trifunović, Branka Šošić Jurjević, Nataša Ristić, Nataša Nestorović, Branko Filipović, Ivana Stevanović, Vesna Begović-Kuprešanin, Milica Manojlović-Stojanoski. Maternal Dexamethasone Exposure Induces Sex-Specific Changes in Histomorphology and Redox Homeostasis of Rat Placenta. International journal of molecular sciences. 2022 Dec; 24(1):. doi: 10.3390/ijms24010540. [PMID: 36613982]
  • Baocheng Xie, Huan Zhou, Hongyu Liu, Shiyi Liao, Chenhui Zhou, Daohua Xu. Salidroside alleviates dexamethasone-induced inhibition of bone formation via transforming growth factor-beta/Smad2/3 signaling pathway. Phytotherapy research : PTR. 2022 Dec; ?(?):. doi: 10.1002/ptr.7711. [PMID: 36567454]
  • Yan-Qing Li, Pan-Na Huang, Hao-Zhe Zhang, Lu-Yu Han, Ruo-Xiang Miao, Wan-Yun Feng, Hua Pan, Lin Feng, Xin-Hua Wu, Juan He, Xu Teng, Xiao-Ning Wang. [Chronic psychological stress exacerbates aortic medial calcification via glucocorticoids]. Sheng li xue bao : [Acta physiologica Sinica]. 2022 Dec; 74(6):927-938. doi: . [PMID: 36594381]
  • Nasrin Sultana, Rafiqul Islam, Rekha Rani Das, Ziaul Haque, Kazi Rafiq, Md Abu Hadi Noor Ali Khan. Steroid growth promoter modified glucose profile and liver morphology in broiler by altering the localization and expression pattern of hepatic glucocorticoid receptors. Research in veterinary science. 2022 Dec; 152(?):277-288. doi: 10.1016/j.rvsc.2022.08.024. [PMID: 36063605]
  • G M Li, Y B Jin, Y Z Gan, C Chen, Y Jia, C Li. [Ruxolitinib as an effective treatment for panniculitis associated hemophagocytic syndrome: A report of 2 cases and literature review]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences. 2022 Dec; 54(6):1208-1213. doi: . [PMID: 36533357]
  • Wei Zhang, Chunzhao Li, Chunmei Zhao, Nan Ji, Fang Luo. Pre-incisional infiltration with ropivacaine plus dexamethasone palmitate emulsion for postoperative pain in patients undergoing craniotomy: study protocol for a prospective, randomized controlled trial. Trials. 2022 Dec; 23(1):996. doi: 10.1186/s13063-022-06936-z. [PMID: 36510271]
  • Idara Asuquo Okon, Justin Atiang Beshel, Victor Udo Nna, Daniel Udofia Owu. Gongronema latifolium leaf extract protects against dexamethasone-induced myocardial cell injury via cardiac oxido-inflammatory molecules modulation. Journal of food biochemistry. 2022 12; 46(12):e14378. doi: 10.1111/jfbc.14378. [PMID: 35976861]
  • Qing Chen, Liping Shao, Yong Li, Mian Dai, He Liu, Nan Xiang, Hui Chen. Tanshinone IIA alleviates ovalbumin-induced allergic rhinitis symptoms by inhibiting Th2 cytokine production and mast cell histamine release in mice. Pharmaceutical biology. 2022 Dec; 60(1):326-333. doi: 10.1080/13880209.2022.2034894. [PMID: 35167426]