D-Lactaldehyde (BioDeep_00000014566)
Secondary id: BioDeep_00001869232
human metabolite Endogenous
代谢物信息卡片
化学式: C3H6O2 (74.0368)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(lipidsearch) 6.39%
分子结构信息
SMILES: CC(C=O)O
InChI: InChI=1S/C3H6O2/c1-3(5)2-4/h2-3,5H,1H3/t3-/m1/s1
描述信息
D- and L-lactaldehyde are also good substrates for aldose reductase. The aldose reductase-catalyzed reduction of methylglyoxal produces 95\\% acetol, 5\\% D-lactaldehyde. (PMID: 1537826). D-lactaldehyde is an intermediate in the pyruvate metabolic pathway. Pyruvaldehyde is irreversibly produced from D-lactaldehyde via the enzyme glyoxylate reductase (NADP+, Swiss-Prot: Q5T945).
D- and L-lactaldehyde are also good substrates for aldose reductase. The aldose reductase-catalyzed reduction of methylglyoxal produces 95\\% acetol, 5\\% D-lactaldehyde. (PMID: 1537826)
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:17167
- KEGG: C00937
- PubChem: 439350
- HMDB: HMDB0006458
- Wikipedia: Lactaldehyde
- MetaCyc: CPD-358
- foodb: FDB023918
- chemspider: 388473
- CAS: 3946-09-6
- PubChem: 4189
- 3DMET: B00204
- NIKKAJI: J2.583F
分类词条
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
27 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(5)
- methylglyoxal degradation VI:
(R)-lactate + an oxidized c-type cytochrome ⟶ H+ + a reduced c-type cytochrome + pyruvate - methylglyoxal degradation VI:
(R)-lactaldehyde + H2O + NAD+ ⟶ (R)-lactate + H+ + NADH - 1,2-propanediol biosynthesis from lactate (engineered):
(S)-propane-1,2-diol + NADP+ ⟶ (S)-lactaldehyde + H+ + NADPH - methylglyoxal degradation VI:
(R)-lactate + an oxidized c-type cytochrome ⟶ a reduced c-type cytochrome + pyruvate - methylglyoxal degradation VI:
(R)-lactate + an oxidized c-type cytochrome ⟶ a reduced c-type cytochrome + pyruvate
WikiPathways(0)
Plant Reactome(0)
INOH(0)
COVID-19 Disease Map(0)
PathBank(21)
- Pyruvate Metabolism:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Leigh Syndrome:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency):
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Pyruvate Dehydrogenase Complex Deficiency:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Primary Hyperoxaluria II, PH2:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Pyruvate Kinase Deficiency:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Pyruvate Metabolism:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Leigh Syndrome:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Dehydrogenase Complex Deficiency:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency):
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Primary Hyperoxaluria II, PH2:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Kinase Deficiency:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Metabolism:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Metabolism:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Metabolism:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Pyruvate Metabolism:
Acetic acid + Coenzyme A ⟶ Acetyl-CoA + Water - Leigh Syndrome:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Dehydrogenase Complex Deficiency:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency):
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Primary Hyperoxaluria II, PH2:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH - Pyruvate Kinase Deficiency:
Acetaldehyde + NAD + Water ⟶ Acetic acid + Hydrogen Ion + NADH
PharmGKB(0)
2 个相关的物种来源信息
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
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