L-Arabitol (BioDeep_00000014434)
Main id: BioDeep_00000406114
Secondary id: BioDeep_00001868413
human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019
代谢物信息卡片
(2S,4S)-pentane-1,2,3,4,5-pentol
化学式: C5H12O5 (152.06847019999998)
中文名称: L-(-)-阿拉伯糖醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(C(C(CO)O)O)O)O
InChI: InChI=1S/C5H12O5/c6-1-3(8)5(10)4(9)2-7/h3-10H,1-2H2/t3-,4-/m0/s1
描述信息
L-Arabitol, also known as L-arabinitol or L-lyxitol, is a member of the class of compounds known as sugar alcohols. Sugar alcohols are hydrogenated forms of carbohydrate in which the carbonyl group (aldehyde or ketone reducing sugar) has been reduced to a primary or secondary hydroxyl group. L-Arabitol is soluble in water. L-Arabitol can be found in a number of food items such as sweet potato, deerberry, moth bean, and European chestnut, which makes L-arabitol a potential biomarker for the consumption of these food products. L-Arabitol can be found in most biofluids, including urine, cerebrospinal fluid (CSF), saliva, and blood. L-Arabitol exists in all living species, ranging from bacteria to humans. Moreover, L-arabitol is found to be associated with Alzheimers disease and ribose-5-phosphate isomerase deficiency, which is an inborn error of metabolism. L-Arabitol can be formed by the reduction of either arabinose or lyxose. L-Arabitol has been reported in pentosuric acidemia (PMID:13525419). L-Arabinosinuia has been described in a patient, presented at the age of 16 months with delayed motor development and facial dysmorphism (PMID:12359133) Congenital liver cirrhosis has been recently described in a patient with highly elevated plasma and urine levels of arabitol due to transaldolase deficiency (Inherit Metab Dis 23(Suppl. 1):172, 2000).
L-Arabitol has been reported in pentosuric acidemia (PMID 13525419). L-Arabinosinuia has been described in a patient, presented at the age of 16 months with delayed motor development and facial dysmorphism. (PMID 12359133) Congenital liver cirrhosis has been recently described in a patient with highly elevated plasma and urine levels of arabitol due to transaldolase deficiency. (Inherit Metab Dis 23(Suppl. 1):172, 2000.) [HMDB]. L-Arabitol is found in many foods, some of which are red raspberry, sweet orange, dandelion, and hyssop.
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L-Arabinitol is a potential biomarker for the comsuption of the food products such as sweet potato, deerberry, moth bean, and is also associated with Alzheimer's disease and ribose-5-phosphate isomerase deficiency.
同义名列表
22 个代谢物同义名
(2S,4S)-pentane-1,2,3,4,5-pentol; 1,2,3,4,5-Pentahydroxypentane; Arabitol, (L)-isomer; Arabitol, (D)-isomer; L-(-)-Arabinitol; Arabino-pentitol; Adonite adonitol; L-(−)-Arabitol; L-(-)-Arabitol; L-(+)-Arabitol; (+--)-Arabitol; L(-)-Arabitol; D-arabinitol; L-Arabinitol; DL-Arabitol; D-Arabitol; L-Arabitol; arabinitol; L-Arabinol; L-Lyxitol; Arabitol; Lyxitol
数据库引用编号
17 个数据库交叉引用编号
- ChEBI: CHEBI:18403
- KEGG: C00532
- PubChem: 439255
- HMDB: HMDB0001851
- Metlin: METLIN141
- Wikipedia: Arabitol
- MetaCyc: L-ARABITOL
- foodb: FDB022709
- chemspider: 388391
- CAS: 7643-75-6
- PubChem: 3814
- PDB-CCD: SST
- 3DMET: B01282
- NIKKAJI: J8.955I
- RefMet: L-Arabitol
- medchemexpress: HY-W040141
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-555
分类词条
相关代谢途径
Reactome(0)
BioCyc(5)
PlantCyc(0)
代谢反应
5 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(4)
- L-arabinose degradation II:
NADP+ + xylitol ⟶ H+ + L-xylulose + NADPH - superpathway of pentose and pentitol degradation:
H2O + L-arabinono-1,4-lactone ⟶ H+ + L-arabinonate - L-arabinose degradation II:
D-xylitol + NADP+ ⟶ H+ + L-xylulose + NADPH - L-arabinose degradation II:
L-arabitol + NADP+ ⟶ H+ + L-arabinose + NADPH
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(1)
- @COVID-19 Disease
Map["name"]:
2-Methyl-3-acetoacetyl-CoA + Coenzyme A ⟶ Acetyl-CoA + Propanoyl-CoA
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
- 46985 - Adonis vernalis: 10.1104/PP.78.4.758
- 9606 - Homo sapiens: -
- 569774 - 金线莲: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Elena A Ianutsevich, Olga A Danilova, Olga A Grum-Grzhimaylo, Vera M Tereshina. Membrane Lipids and Osmolytes in the Response of the Acidophilic Basidiomycete Phlebiopsis gigantea to Heat, Cold, and Osmotic Shocks.
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2024 Mar; 25(6):. doi:
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Fitoterapia.
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