Galactaric acid (BioDeep_00000014362)

 

Secondary id: BioDeep_00000400051

natural product human metabolite PANOMIX_OTCML-2023 Endogenous BioNovoGene_Lab2019


代谢物信息卡片


(2R,3S,4R,5S)-2,3,4,5-Tetrahydroxyhexanedioic acid

化学式: C6H10O8 (210.03756600000003)
中文名称: 粘液酸, 黏酸, 粘酸
谱图信息: 最多检出来源 Viridiplantae(plant) 0.13%

分子结构信息

SMILES: C(C(C(C(=O)O)O)O)(C(C(=O)O)O)O
InChI: InChI=1S/C6H10O8/c7-1(3(9)5(11)12)2(8)4(10)6(13)14/h1-4,7-10H,(H,11,12)(H,13,14)/t1-,2+,3+,4-

描述信息

Galactaric acid, also known as mucic acid or galactarate, belongs to the class of organic compounds known as glucuronic acid derivatives. Glucuronic acid derivatives are compounds containing a glucuronic acid moiety (or a derivative), which consists of a glucose moiety with the C6 carbon oxidized to a carboxylic acid. Technically, galactaric acid is an aldaric acid obtained by oxidation of galactose. Galactaric acid exists as a white crystalline powder, which melts at 210 - 230 oC. It is insoluble in alcohol, and nearly insoluble in cold water (1 g/300 mL) but more soluble in hot water (1 g/60 mL).. Galactaric acid exists in all living organisms, ranging from bacteria to plants to humans. In plants, galactaric acid is commonly produced or utilized as an osmorgulator (PMID: 31505987). Galactaric acid has been detected, but not quantified in, several different foods, such as fruits, vegetables and bovine milk. A recent large-scale dietary study found that galactaric acid can serve as a biomarker for long-term dairy intake and for the consumption of carotenoid-rich vegetables (PMID: 33566801). In food production, galactaric acid can be used to replace tartaric acid in self-rising flour or fizzies.
Present in ripe fruits of peach and pear. Formed in grapes and grape must by the action of Botrytis cinerea on galacturonic acid
Acquisition and generation of the data is financially supported in part by CREST/JST.
Mucic acid is an endogenous metabolite.

同义名列表

27 个代谢物同义名

(2R,3S,4R,5S)-2,3,4,5-Tetrahydroxyhexanedioic acid; (2R,3S,4R,5S)-2,3,4,5-Tetrahydroxyhexanedioate; Strontium galactarate mono-hydrate; Galactaric acid, sodium salt; Galactosaccharic acid; Meso-galactaric acid; Saccharolactic acid; Galactosaccharate; Acido galactarico; D-Galactaric acid; Saccharolactate; Galactaric acid; Galaktarsaeure; Galactarsaeure; Schleimsaeure; D-Galactarate; Hexaric acid; D-Mucic acid; Acido mucico; Schleimsaure; Galactarate; Mucinsaeure; Mucic acid; D-Mucate; Mucate; Mucin; Galactaric acid



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(2)

PharmGKB(0)

11 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Katherine Benavides, Andrés Sánchez-Kopper, Karol Jiménez-Quesada, Raquel Perez, Giovanni Garro-Monge. Evaluation of Salicylic Acid and Methyl Jasmonate as Elicitors in Phyllanthus acuminatus Hairy Roots by Non-Targeted Analysis Using High-Resolution Mass Spectrometry. Molecules (Basel, Switzerland). 2023 Dec; 29(1):. doi: 10.3390/molecules29010080. [PMID: 38202663]
  • A Parthiban, V Sachithanandam, P Lalitha, Jayaraman Muthukumaran, Ranjita Misra, Monika Jain, R Sridhar, T Mageswaran, Ramachandran Purvaja, Ramachandran Ramesh. Isolation, characterisation, anticancer and anti-oxidant activities of 2-methoxy mucic acid from Rhizophora apiculata: an in vitro and in silico studies. Journal of biomolecular structure & dynamics. 2023 Mar; 41(4):1424-1436. doi: 10.1080/07391102.2021.2020688. [PMID: 34963406]
  • Zhibo Song, Tao Chen, Shuo Wang, Cheng Shen, Yumei Ma, Aijing Li, Zhi Chen, Yulin Li. Large-scale preparation of five polar polyphenols including three isomers from Phyllanthus emblica Linn. by preparative high-speed counter-current chromatography. Journal of separation science. 2023 Jan; 46(2):e2200748. doi: 10.1002/jssc.202200748. [PMID: 36337042]
  • Toshihiro Kishikawa, Noriko Arase, Shigeyoshi Tsuji, Yuichi Maeda, Takuro Nii, Jun Hirata, Ken Suzuki, Kenichi Yamamoto, Tatsuo Masuda, Kotaro Ogawa, Shiro Ohshima, Hidenori Inohara, Atsushi Kumanogoh, Manabu Fujimoto, Yukinori Okada. Large-scale plasma-metabolome analysis identifies potential biomarkers of psoriasis and its clinical subtypes. Journal of dermatological science. 2021 May; 102(2):78-84. doi: 10.1016/j.jdermsci.2021.03.006. [PMID: 33836926]
  • Nabil Killiny, Maria Filomena Valim, Shelley E Jones, Ahmad A Omar, Faraj Hijaz, Fred G Gmitter, Jude W Grosser. Metabolically speaking: Possible reasons behind the tolerance of 'Sugar Belle' mandarin hybrid to huanglongbing. Plant physiology and biochemistry : PPB. 2017 Jul; 116(?):36-47. doi: 10.1016/j.plaphy.2017.05.001. [PMID: 28501026]
  • Amaraporn Wongrakpanich, Vijaya B Joshi, Aliasger K Salem. Poly(galactaramidoamine) is an efficient cationic polymeric non-viral vector with low cytotoxicity for transfecting human embryonic kidney (HEK293) and murine macrophage (RAW264.7) cells. Pharmaceutical development and technology. 2013 Sep; 18(5):1255-8. doi: 10.3109/10837450.2011.649856. [PMID: 22235917]
  • Han Han, Mark E Davis. Targeted nanoparticles assembled via complexation of boronic-acid-containing targeting moieties to diol-containing polymers. Bioconjugate chemistry. 2013 Apr; 24(4):669-77. doi: 10.1021/bc300640j. [PMID: 23461746]
  • Janet K Freburger, Leslie J Ng, Brian D Bradbury, Abhijit V Kshirsagar, M Alan Brookhart. Changing patterns of anemia management in US hemodialysis patients. The American journal of medicine. 2012 Sep; 125(9):906-14.e9. doi: 10.1016/j.amjmed.2012.03.011. [PMID: 22938926]
  • Julia Monsénégo, Abdelhak Mansouri, Marie Akkaoui, Véronique Lenoir, Catherine Esnous, Véronique Fauveau, Valentin Tavernier, Jean Girard, Carina Prip-Buus. Enhancing liver mitochondrial fatty acid oxidation capacity in obese mice improves insulin sensitivity independently of hepatic steatosis. Journal of hepatology. 2012 Mar; 56(3):632-9. doi: 10.1016/j.jhep.2011.10.008. [PMID: 22037024]
  • Kahkashan Rashid, Semantee Bhattacharya, Parames C Sil. Protective role of D-saccharic acid-1,4-lactone in alloxan induced oxidative stress in the spleen tissue of diabetic rats is mediated by suppressing mitochondria dependent apoptotic pathway. Free radical research. 2012 Mar; 46(3):240-52. doi: 10.3109/10715762.2011.650694. [PMID: 22239106]
  • Qiong-Lin Liang, Xiao-Ping Liang, Yi-Ming Wang, Yuan-Yuan Xie, Rong-Li Zhang, Xi Chen, Rong Gao, Yi-Jun Cheng, Jun Wu, Qing-Bo Xu, Qing-Zhong Xiao, Xue Li, Shu-Feng Lv, Xue-Mei Fan, Hong-Yang Zhang, Qing-Li Zhang, Guo-An Luo. Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on 'system to system' mode. Journal of translational medicine. 2012 Feb; 10(?):26. doi: 10.1186/1479-5876-10-26. [PMID: 22316391]
  • Pilar Galindo, Isabel Rodriguez-Gómez, Susana González-Manzano, Montserrat Dueñas, Rosario Jiménez, Carmen Menéndez, Félix Vargas, Juan Tamargo, Celestino Santos-Buelga, Francisco Pérez-Vizcaíno, Juan Duarte. Glucuronidated quercetin lowers blood pressure in spontaneously hypertensive rats via deconjugation. PloS one. 2012; 7(3):e32673. doi: 10.1371/journal.pone.0032673. [PMID: 22427863]
  • Vaijinath S Kamanna, Shobha H Ganji, Stanislav Shelkovnikov, Keith Norris, Nosratola D Vaziri. Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration. American journal of nephrology. 2012; 35(2):114-9. doi: 10.1159/000334939. [PMID: 22212390]
  • Semantee Bhattacharya, Prasenjit Manna, Ratan Gachhui, Parames C Sil. D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway. Toxicology and applied pharmacology. 2011 Dec; 257(2):272-83. doi: 10.1016/j.taap.2011.09.013. [PMID: 21982801]
  • Carmen Menendez, Montserrat Dueñas, Pilar Galindo, Susana González-Manzano, Rosario Jimenez, Laura Moreno, Maria José Zarzuelo, Isabel Rodríguez-Gómez, Juan Duarte, Celestino Santos-Buelga, Francisco Perez-Vizcaino. Vascular deconjugation of quercetin glucuronide: the flavonoid paradox revealed?. Molecular nutrition & food research. 2011 Dec; 55(12):1780-90. doi: 10.1002/mnfr.201100378. [PMID: 22144045]
  • Yeonsoo Kim, Sonhee C Park, Bryan W Wolf, Steven R Hertzler. Combination of erythritol and fructose increases gastrointestinal symptoms in healthy adults. Nutrition research (New York, N.Y.). 2011 Nov; 31(11):836-41. doi: 10.1016/j.nutres.2011.09.025. [PMID: 22118754]
  • Stefan Safer, Serhat S Cicek, Valerio Pieri, Stefan Schwaiger, Peter Schneider, Volker Wissemann, Hermann Stuppner. Metabolic fingerprinting of Leontopodium species (Asteraceae) by means of ¹H NMR and HPLC-ESI-MS. Phytochemistry. 2011 Aug; 72(11-12):1379-89. doi: 10.1016/j.phytochem.2011.04.006. [PMID: 21550615]
  • L Adhikary, S Acharya. Efficacy of IV iron compared to oral iron for increment of haemoglobin level in anemic chronic kidney disease patients on erythropoietin therapy. JNMA; journal of the Nepal Medical Association. 2011 Jul; 51(183):133-6. doi: 10.31729/jnma.32. [PMID: 22922860]
  • Vijay P Taori, Hao Lu, Theresa M Reineke. Structure-activity examination of poly(glycoamidoguanidine)s: glycopolycations containing guanidine units for nucleic acid delivery. Biomacromolecules. 2011 Jun; 12(6):2055-63. doi: 10.1021/bm101537f. [PMID: 21506608]
  • Joanna Kolodziejczyk, Joanna Saluk-Juszczak, Barbara Wachowicz. In vitro study of the antioxidative properties of the glucose derivatives against oxidation of plasma components. Journal of physiology and biochemistry. 2011 Jun; 67(2):175-83. doi: 10.1007/s13105-010-0061-3. [PMID: 21086198]
  • Oswaldo Hernández-Hernández, Laura Ruiz-Aceituno, María Luz Sanz, Isabel Martínez-Castro. Determination of free inositols and other low molecular weight carbohydrates in vegetables. Journal of agricultural and food chemistry. 2011 Mar; 59(6):2451-5. doi: 10.1021/jf1045552. [PMID: 21366313]
  • Marilyn G Wiebe, Dominik Mojzita, Satu Hilditch, Laura Ruohonen, Merja Penttilä. Bioconversion of D-galacturonate to keto-deoxy-L-galactonate (3-deoxy-L-threo-hex-2-ulosonate) using filamentous fungi. BMC biotechnology. 2010 Aug; 10(?):63. doi: 10.1186/1472-6750-10-63. [PMID: 20796274]
  • Zhong-Wei Zhang, Shu Yuan, Fei Xu, Hui Yang, Nian-Hui Zhang, Jian Cheng, Hong-Hui Lin. The plastid hexokinase pHXK: a node of convergence for sugar and plastid signals in Arabidopsis. FEBS letters. 2010 Aug; 584(16):3573-9. doi: 10.1016/j.febslet.2010.07.024. [PMID: 20650273]
  • Susan C Connor, Michael K Hansen, Adam Corner, Randall F Smith, Terence E Ryan. Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. Molecular bioSystems. 2010 May; 6(5):909-21. doi: 10.1039/b914182k. [PMID: 20567778]
  • Lei O Li, Yun-Fu Hu, Lily Wang, Matthew Mitchell, Alvin Berger, Rosalind A Coleman. Early hepatic insulin resistance in mice: a metabolomics analysis. Molecular endocrinology (Baltimore, Md.). 2010 Mar; 24(3):657-66. doi: 10.1210/me.2009-0152. [PMID: 20150186]
  • Krista Rombouts, Fabio Marra. Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis. Digestive diseases (Basel, Switzerland). 2010; 28(1):229-35. doi: 10.1159/000282094. [PMID: 20460917]
  • Shigefumi Morimoto, Toshiki Koda, Tomoki Suidzu, Ryunosuke Uranishi, Yoshiharu Shono, Isao Akiyama, Kumiyo Shimizu, Yoshikazu Fujita, Kenji Hasegawa, Katsuyoshi Tabuse. Significance of urinary glucaric acid measurement and its application to paclitaxel therapy. Gan to kagaku ryoho. Cancer & chemotherapy. 2009 Nov; 36(11):1857-61. doi: . [PMID: 19920388]
  • Chun-Xia Yi, Mireille J Serlie, Mariette T Ackermans, Ewout Foppen, Ruud M Buijs, Hans P Sauerwein, Eric Fliers, Andries Kalsbeek. A major role for perifornical orexin neurons in the control of glucose metabolism in rats. Diabetes. 2009 Sep; 58(9):1998-2005. doi: 10.2337/db09-0385. [PMID: 19592616]
  • Stefano Costa, Stefan Schwaiger, Rinaldo Cervellati, Hermann Stuppner, Ester Speroni, Maria Clelia Guerra. In vitro evaluation of the chemoprotective action mechanisms of leontopodic acid against aflatoxin B1 and deoxynivalenol-induced cell damage. Journal of applied toxicology : JAT. 2009 Jan; 29(1):7-14. doi: 10.1002/jat.1372. [PMID: 18636399]
  • Pedro Gonçalves, João R Araújo, Fátima Martel. The effect of high glucose on SERT, the human plasmalemmal serotonin transporter. Nutritional neuroscience. 2008 Dec; 11(6):244-50. doi: 10.1179/147683008x344156. [PMID: 19000377]
  • Robert Zółtaszek, Margaret Hanausek, Zofia M Kiliańska, Zbigniew Walaszek. [The biological role of D-glucaric acid and its derivatives: potential use in medicine]. Postepy higieny i medycyny doswiadczalnej (Online). 2008 Sep; 62(?):451-62. doi: . [PMID: 18772850]
  • Richard S Lord, J Alexander Bralley. Clinical applications of urinary organic acids. Part I: Detoxification markers. Alternative medicine review : a journal of clinical therapeutic. 2008 Sep; 13(3):205-15. doi: NULL. [PMID: 18950247]
  • Lauren Oleson, Michael H Court. Effect of the beta-glucuronidase inhibitor saccharolactone on glucuronidation by human tissue microsomes and recombinant UDP-glucuronosyltransferases. The Journal of pharmacy and pharmacology. 2008 Sep; 60(9):1175-82. doi: 10.1211/jpp.60.9.0009. [PMID: 18718121]
  • Susanne M Picker, Alexander Steisel, Birgit S Gathof. Effects of Mirasol PRT treatment on storage lesion development in plasma-stored apheresis-derived platelets compared to untreated and irradiated units. Transfusion. 2008 Aug; 48(8):1685-92. doi: 10.1111/j.1537-2995.2008.01778.x. [PMID: 18513255]
  • Joanna Saluk-Juszczak, Beata Olas, Paweł Nowak, Agnieszka Staroń, Barbara Wachowicz. Protective effects of D-glucaro-1,4-lactone against oxidative modifications in blood platelets. Nutrition, metabolism, and cardiovascular diseases : NMCD. 2008 Jul; 18(6):422-8. doi: 10.1016/j.numecd.2007.02.016. [PMID: 17933501]
  • Kyung-Bum Lee, Philippe De Backer, Toshihiro Aono, Chi-Te Liu, Shino Suzuki, Tadahiro Suzuki, Takakazu Kaneko, Manabu Yamada, Satoshi Tabata, Doris M Kupfer, Fares Z Najar, Graham B Wiley, Bruce Roe, Tim T Binnewies, David W Ussery, Wim D'Haeze, Jeroen Den Herder, Dirk Gevers, Danny Vereecke, Marcelle Holsters, Hiroshi Oyaizu. The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571. BMC genomics. 2008 Jun; 9(?):271. doi: 10.1186/1471-2164-9-271. [PMID: 18522759]
  • Beata Olas, Joanna Saluk-Juszczak, Barbara Wachowicz. D-glucaro 1,4-lactone and resveratrol as antioxidants in blood platelets. Cell biology and toxicology. 2008 Apr; 24(2):189-99. doi: 10.1007/s10565-007-9028-8. [PMID: 17846905]
  • Kohei Hasegawa, Kumiyo Shimidzu, Shigehumi Morimoto, Yoshimi Hachino, Kenji Hasegawa, Yoshiharu Shono, Tetuya Horiuchi, Katsuyoshi Tabuse, Yurina Masui, Takako Yamaguchi, Yoshikazu Fujita. [Improvement of urinary d-glucaric acid assay and its application]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2008 Jan; 128(1):135-40. doi: 10.1248/yakushi.128.135. [PMID: 18176065]
  • Beata Olas, Joanna Saluk-Juszczak, Pawel Nowak, Rafal Glowacki, Edward Bald, Barbara Wachowicz. Protective effects of D-glucaro 1,4-lactone against oxidative/nitrative modifications of plasma proteins. Nutrition (Burbank, Los Angeles County, Calif.). 2007 Feb; 23(2):164-71. doi: 10.1016/j.nut.2006.11.003. [PMID: 17234507]
  • Charu Sudan, Shiva Prakash, Prasanna Bhomkar, Shalu Jain, Neera Bhalla-Sarin. Ubiquitous presence of beta-glucuronidase (GUS) in plants and its regulation in some model plants. Planta. 2006 Sep; 224(4):853-64. doi: 10.1007/s00425-006-0276-2. [PMID: 16652220]
  • Yemin Liu, Theresa M Reineke. Poly(glycoamidoamine)s for gene delivery: stability of polyplexes and efficacy with cardiomyoblast cells. Bioconjugate chemistry. 2006 Jan; 17(1):101-8. doi: 10.1021/bc050275+. [PMID: 16417257]
  • Maria J Tutor-Crespo, Jesús Hermida, J Carlos Tutor. Effect of antiepileptic drugs on the urinary excretion of porphyrins in non-porphyric subjects. Journal of pharmacological sciences. 2005 Dec; 99(4):323-8. doi: 10.1254/jphs.fpe05003x. [PMID: 16314692]
  • Pierre Ayotte, Eric Dewailly, George H Lambert, Sherry L Perkins, Raymond Poon, Mark Feeley, Christian Larochelle, Daria Pereg. Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines. Environmental health perspectives. 2005 Oct; 113(10):1318-24. doi: 10.1289/ehp.7970. [PMID: 16203240]
  • María J Tutor-Crespo, Jesús Hermida, J Carlos Tutor. Possible induction of cholinesterase in epileptic patients treated with anticonvulsant drugs: relationship with lipoprotein levels. Journal of clinical pharmacology. 2004 Sep; 44(9):974-80. doi: 10.1177/0091270004266486. [PMID: 15317825]
  • María J Tutor-Crespo, Jesús Hermida, J Carlos Tutor. Assessment of copper status in epileptic patients treated with anticonvulsant drugs by measuring the specific oxidase activity of ceruloplasmin. Epilepsy research. 2003 Oct; 56(2-3):147-53. doi: 10.1016/j.eplepsyres.2003.08.008. [PMID: 14642999]
  • P Apostoli, A Mangili, S Carasi, M Manno. Relationship between PCBs in blood and D-glucaric acid in urine. Toxicology letters. 2003 Sep; 144(1):17-26. doi: 10.1016/s0378-4274(03)00226-1. [PMID: 12919720]
  • I V Mukhin, V Iu Nikolenko. [Experimental systemic enzyme therapy of gouty and primary glomerulonephritis]. Eksperimental'naia i klinicheskaia farmakologiia. 2003 Jul; 66(4):32-5. doi: NULL. [PMID: 14558349]
  • Margaret Hanausek, Zbigniew Walaszek, Thomas J Slaga. Detoxifying cancer causing agents to prevent cancer. Integrative cancer therapies. 2003 Jun; 2(2):139-44. doi: 10.1177/1534735403002002005. [PMID: 15035900]
  • Steffen Bauer, Elke Störmer, Reinhold Kerb, Andreas Johne, Jürgen Brockmöller, Ivar Roots. Differential effects of Saint John's Wort (hypericum perforatum) on the urinary excretion of D-glucaric acid and 6beta-hydroxycortisol in healthy volunteers. European journal of clinical pharmacology. 2002 Dec; 58(9):581-5. doi: 10.1007/s00228-002-0527-5. [PMID: 12483450]
  • M J Tutor-Crespo, J Hermida-Ameijeiras, J C Tutor-Valcarce. [A study of some indirect biochemical markers in the evaluation of enzymatic induction caused by antiepileptic drugs]. Revista de neurologia. 2002 Oct; 35(8):711-6. doi: NULL. [PMID: 12402220]
  • ". Calcium-D-glucarate. Alternative medicine review : a journal of clinical therapeutic. 2002 Aug; 7(4):336-9. doi: ". [PMID: 12197785]
  • Jesús Hermida, M Pilar Fernández, J Carlos Tutor. Relationship between changes in drug score, D-glucaric acid excretion, and gamma-glutamyltransferase and beta-glucuronidase serum activities during anticonvulsant treatment. Clinical laboratory. 2002; 48(7-8):415-9. doi: . [PMID: 12146576]
  • J Pach, A Hubalewska-Hoła, Z Szybiński, D Pach. New possibilities in scintigraphy detection of carbon monoxide cardiotoxicity. Przeglad lekarski. 2001; 58(4):182-4. doi: NULL. [PMID: 11450331]
  • R S JONES, Y C MAYNE. Experimental nephrolithiasis with mucic acid. Laboratory investigation; a journal of technical methods and pathology. 1957 Nov; 6(6):508-21. doi: NULL. [PMID: 13476641]