5-Hydroxybenzimidazole (BioDeep_00000014247)

5-Hydroxybenzimidazole

分子结构信息

SMILES: C1=CC2=C(C=C1O)NC=N2
InChI: InChI=1S/C7H6N2O/c10-5-1-2-6-7(3-5)9-4-8-6/h1-4,10H,(H,8,9)

A member of the class of benzimidazoles that is 1H-benzimidazole carrying a single hydroxy substituent at position 5.

1 个代谢物同义名

9 个数据库交叉引用编号

4 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(4)

5-hydroxybenzimidazolyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP: 5-hydroxybenzimidazole + NaMN ⟶ 5-hydroxybenzimidazole ribotide phosphate + H⁺ + nicotinate
5,6-dimethylbenzimidazole biosynthesis II (anaerobic): 5-hydroxybenzimidazole + SAM ⟶ 5-methoxybenzimidazole + H⁺ + SAH
5-hydroxybenzimidazolyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP: 5-hydroxybenzimidazole + NaMN ⟶ 5-hydroxybenzimidazole ribotide phosphate + H⁺ + nicotinate
5-hydroxybenzimidazolyl adenosylcobamide biosynthesis from adenosylcobinamide-GDP: 5-hydroxybenzimidazole + NaMN ⟶ 5-hydroxybenzimidazole ribotide phosphate + H⁺ + nicotinate

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

Angad P Mehta, Sameh H Abdelwahed, Michael K Fenwick, Amrita B Hazra, Michiko E Taga, Yang Zhang, Steven E Ealick, Tadhg P Begley. Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis. Journal of the American Chemical Society. 2015 Aug; 137(33):10444-7. doi: 10.1021/jacs.5b03576. [PMID: 26237670]
Amrita B Hazra, Andrew W Han, Angad P Mehta, Kenny C Mok, Vadim Osadchiy, Tadhg P Begley, Michiko E Taga. Anaerobic biosynthesis of the lower ligand of vitamin B12. Proceedings of the National Academy of Sciences of the United States of America. 2015 Aug; 112(34):10792-7. doi: 10.1073/pnas.1509132112. [PMID: 26246619]
N L Sakina, A M Golubkov, L D Smirnov, M A Ostrovsky, A E Dontsov. Studying the photoprotective activity of a new class of heteroaromatic antioxidants. Bulletin of experimental biology and medicine. 2009 Feb; 147(2):193-5. doi: 10.1007/s10517-009-0472-8. [PMID: 19513419]