Norsolorinic acid (BioDeep_00000013455)
代谢物信息卡片
化学式: C20H18O7 (370.1052478)
中文名称:
谱图信息:
最多检出来源 Macaca mulatta(otcml) 0.29%
分子结构信息
SMILES: c1c(cc2c(c1O)C(=O)c1c(C2=O)cc(c(c1O)C(=O)CCCCC)O)O
InChI: InChI=1S/C20H18O7/c1-2-3-4-5-12(22)17-14(24)8-11-16(20(17)27)19(26)15-10(18(11)25)6-9(21)7-13(15)23/h6-8,21,23-24,27H,2-5H2,1H3
描述信息
A polyketide that is anthraquinone bearing four hydroxy substituents at positions 1, 3, 6 and 8 as well as a hexanoyl substituent at position 2.
同义名列表
1 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:71356
- KEGG: C20452
- PubChem: 25102
- KNApSAcK: C00000561
- CAS: 10254-99-6
- PMhub: MS000027919
- MetaboLights: MTBLC71356
- PubChem: 163312189
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
8 个相关的物种来源信息
- 5059 - Aspergillus flavus:
- 91484 - Aspergillus navahoensis:
- 162425 - Aspergillus nidulans: 10.1111/J.1742-7843.2008.00237.X
- 41061 - Aspergillus nomiae: 10.1039/C39800000183
- 5067 - Aspergillus parasiticus:
- 46472 - Aspergillus versicolor: 10.1271/BBB1961.31.1513
- 153742 - Cinchona calisaya: 10.1055/S-2006-962510
- 48864 - Solorina crocea: 10.1016/S0031-9422(00)85363-7
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Clay C C Wang, Yi-Ming Chiang, Po-Lin Kuo, Jiunn-Kae Chang, Ya-Ling Hsu. Norsolorinic acid from Aspergillus nidulans inhibits the proliferation of human breast adenocarcinoma MCF-7 cells via Fas-mediated pathway.
Basic & clinical pharmacology & toxicology.
2008 Jun; 102(6):491-7. doi:
10.1111/j.1742-7843.2008.00237.x. [PMID: 18346044] - Lori A Maggio-Hall, Richard A Wilson, Nancy P Keller. Fundamental contribution of beta-oxidation to polyketide mycotoxin production in planta.
Molecular plant-microbe interactions : MPMI.
2005 Aug; 18(8):783-93. doi:
10.1094/mpmi-18-0783. [PMID: 16134890] - N P Keller, C M Watanabe, H S Kelkar, T H Adams, C A Townsend. Requirement of monooxygenase-mediated steps for sterigmatocystin biosynthesis by Aspergillus nidulans.
Applied and environmental microbiology.
2000 Jan; 66(1):359-62. doi:
10.1128/aem.66.1.359-362.2000. [PMID: 10618248] - C P Woloshuk, R Prieto. Genetic organization and function of the aflatoxin B1 biosynthetic genes.
FEMS microbiology letters.
1998 Mar; 160(2):169-76. doi:
10.1111/j.1574-6968.1998.tb12907.x. [PMID: 9532734] - R T Awuah, K A Kpodo. High incidence of Aspergillus flavus and aflatoxins in stored groundnut in Ghana and the use of a microbial assay to assess the inhibitory effects of plant extracts on aflatoxin synthesis.
Mycopathologia.
1996; 134(2):109-14. doi:
10.1007/bf00436873. [PMID: 8981776] - G H Feng, T J Leonard. Characterization of the polyketide synthase gene (pksL1) required for aflatoxin biosynthesis in Aspergillus parasiticus.
Journal of bacteriology.
1995 Nov; 177(21):6246-54. doi:
10.1128/jb.177.21.6246-6254.1995. [PMID: 7592391]