16-oxo-palmitate (BioDeep_00000012959)

 

Secondary id: BioDeep_00001870272

natural product


代谢物信息卡片


16-oxohexadecanoic acid

化学式: C16H30O3 (270.21948299999997)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 0.22%

分子结构信息

SMILES: C(CCCCCCCC(=O)O)CCCCCCC=O
InChI: InChI=1S/C16H30O3/c17-15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16(18)19/h15H,1-14H2,(H,18,19)

描述信息

同义名列表

2 个代谢物同义名

16-oxohexadecanoic acid; 16-oxo-palmitate



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lijun Tian, Heather McClafferty, Hans-Guenther Knaus, Peter Ruth, Michael J Shipston. Distinct acyl protein transferases and thioesterases control surface expression of calcium-activated potassium channels. The Journal of biological chemistry. 2012 Apr; 287(18):14718-25. doi: 10.1074/jbc.m111.335547. [PMID: 22399288]
  • Mark N Adams, Melinda E Christensen, Yaowu He, Nigel J Waterhouse, John D Hooper. The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2. PloS one. 2011; 6(11):e28018. doi: 10.1371/journal.pone.0028018. [PMID: 22140500]
  • Lisa M Galli, Laura W Burrus. Differential palmit(e)oylation of Wnt1 on C93 and S224 residues has overlapping and distinct consequences. PloS one. 2011; 6(10):e26636. doi: 10.1371/journal.pone.0026636. [PMID: 22046319]
  • Jennifer Greaves, Oforiwa A Gorleku, Christine Salaun, Luke H Chamberlain. Palmitoylation of the SNAP25 protein family: specificity and regulation by DHHC palmitoyl transferases. The Journal of biological chemistry. 2010 Aug; 285(32):24629-38. doi: 10.1074/jbc.m110.119289. [PMID: 20519516]
  • Lijun Tian, Heather McClafferty, Owen Jeffries, Michael J Shipston. Multiple palmitoyltransferases are required for palmitoylation-dependent regulation of large conductance calcium- and voltage-activated potassium channels. The Journal of biological chemistry. 2010 Jul; 285(31):23954-62. doi: 10.1074/jbc.m110.137802. [PMID: 20507996]
  • Pleasantine Mill, Angela W S Lee, Yuko Fukata, Ryouhei Tsutsumi, Masaki Fukata, Margaret Keighren, Rebecca M Porter, Lisa McKie, Ian Smyth, Ian J Jackson. Palmitoylation regulates epidermal homeostasis and hair follicle differentiation. PLoS genetics. 2009 Nov; 5(11):e1000748. doi: 10.1371/journal.pgen.1000748. [PMID: 19956733]
  • Karine H Hellemans, Jean-Claude Hannaert, Bart Denys, Knut R Steffensen, Cindy Raemdonck, Geert A Martens, Paul P Van Veldhoven, Jan-Ake Gustafsson, Daniel Pipeleers. Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase. PloS one. 2009 Sep; 4(9):e7266. doi: 10.1371/journal.pone.0007266. [PMID: 19787047]
  • Sonia L Planey, David A Zacharias. Palmitoyl acyltransferases, their substrates, and novel assays to connect them (Review). Molecular membrane biology. 2009 Jan; 26(1):14-31. doi: 10.1080/09687680802646703. [PMID: 19191172]
  • Byung Chul Lee, Dong Hyun Kim, Iljung Lee, Yearn Seong Choe, Dae Yoon Chi, Kyung-Han Lee, Yong Choi, Byung-Tae Kim. 16-Cyclopentadienyl tricarbonyl 99mTc 16-oxo-hexadecanoic acid: synthesis and evaluation of fatty acid metabolism in mouse myocardium. Journal of medicinal chemistry. 2008 Jun; 51(12):3630-4. doi: 10.1021/jm800049h. [PMID: 18503263]
  • Vladimir L Katanaev, Gonzalo P Solis, George Hausmann, Silke Buestorf, Natalya Katanayeva, Yvonne Schrock, Claudia A O Stuermer, Konrad Basler. Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila. The EMBO journal. 2008 Feb; 27(3):509-21. doi: 10.1038/sj.emboj.7601981. [PMID: 18219274]
  • Jeremiah M Draper, Zuping Xia, Charles D Smith. Cellular palmitoylation and trafficking of lipidated peptides. Journal of lipid research. 2007 Aug; 48(8):1873-84. doi: 10.1194/jlr.m700179-jlr200. [PMID: 17525474]
  • Cheng Fang, Lunbin Deng, Cheryl A Keller, Masaki Fukata, Yuko Fukata, Gong Chen, Bernhard Lüscher. GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006 Dec; 26(49):12758-68. doi: 10.1523/jneurosci.4214-06.2006. [PMID: 17151279]
  • Kun Huang, Alaa El-Husseini. Modulation of neuronal protein trafficking and function by palmitoylation. Current opinion in neurobiology. 2005 Oct; 15(5):527-35. doi: 10.1016/j.conb.2005.08.001. [PMID: 16125924]