Captafol (BioDeep_00000012408)

 

Secondary id: BioDeep_00001867928

human metabolite Endogenous


代谢物信息卡片


3a,4,7,7a-Tetrahydro-2-[(1,1,2,2-tetrachloroethyl)thio]-1H-isoindole-1,3(2H)-dione, 9ci

化学式: C10H9Cl4NO2S (346.9108094)
中文名称: 敌菌丹
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CCC2C(C1)C(=O)N(C2=O)SC(C(Cl)Cl)(Cl)Cl
InChI: InChI=1S/C10H9Cl4NO2S/c11-9(12)10(13,14)18-15-7(16)5-3-1-2-4-6(5)8(15)17/h1-2,5-6,9H,3-4H2

描述信息

Nonsystemic foliar agricultural fungicide, especially for potatoe
D016573 - Agrochemicals
D010575 - Pesticides

同义名列表

37 个代谢物同义名

3a,4,7,7a-Tetrahydro-2-[(1,1,2,2-tetrachloroethyl)thio]-1H-isoindole-1,3(2H)-dione, 9ci; 2-[(1,1,2,2-tetrachloroethyl)sulfanyl]-2,3,3a,4,7,7a-hexahydro-1H-isoindole-1,3-dione; 3a,4,7,7a-Tetrahydro-2-[(1,1,2,2-tetrachloroethyl)thio]-1H-isoindole-1,3(2H)-dione; N-[(1,1,2,2-Tetrachloroethyl)sulphenyl]-4-cyclohexene-1,2-dicarboximide; 3a,4,7,7a-Tetrahydro-N-(1,1,2,2-tetrachloroethanesulphenyl)phthalimide; N-[(1,1,2,2-Tetrachloroethyl)sulfenyl]-4-cyclohexene-1,2-dicarboximide; 3a,4,7,7a-Tetrahydro-N-(1,1,2,2-tetrachloroethanesulfenyl)phthalimide; N-(1,1,2,2-Tetrachloroethylthio)-4-cyclohexene-1,2-dicarboximide, 8ci; N-1,1,2,2-Tetrachloroethylmercapto-4-cyclohexene-1,2-carboximide; N-(1,1,2,2-Tetrachloroethylthio)-Delta(4)-tetrahydrophthalimide; 1,2,3,6-Tetrahydro-N-(1,1,2,2-tetrachloroethylthio)phthalimide; N-(1,1,2,2-Tetrachloroethylthio)-δ(4)-tetrahydrophthalimide; N-(Tetrachloroethylthio)tetrahydrophthalimide; (Tetrachloroethylthio)tetrahydrophthalimide; Tetrachloroethylthiotetrahydrophthalimide; Captafol, (cis)-isomer; Difolatan, jmaf; Saprirearine; crisfolatan; Nalco 7046; Proxel ef; Difolatan; Arborseal; Captaspor; Haipen 50; Captofol; Captefol; Captafol; Terrazol; Merpafol; Kenofol; Difosan; Sanspor; Alfloc; Haipen; Folcid; Foltaf



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Stanislav A Pshenichnyuk, Alexei S Komolov. Why Can Unnatural Electron Acceptors Protect Photosynthesizing Organisms but Kill the Others?. The journal of physical chemistry. B. 2017 02; 121(4):749-757. doi: 10.1021/acs.jpcb.6b12007. [PMID: 28072544]
  • ". Final report on carcinogens background document for captafol. Report on carcinogens background document for [substance name]. 2008 Jun; ?(8-5974):i-xvi, 1. doi: ". [PMID: 20737006]
  • Luigi Robbiano, Debora Baroni, Roberto Carrozzino, Eugenio Mereto, Giovanni Brambilla. DNA damage and micronuclei induced in rat and human kidney cells by six chemicals carcinogenic to the rat kidney. Toxicology. 2004 Nov; 204(2-3):187-95. doi: 10.1016/j.tox.2004.06.057. [PMID: 15388244]
  • H C Kim, S W Cha, S W Song, C S Ha, S S Han, J K Roh, Y S Lee, F Furukawa, A Nishikawa, M Takahashi. Enhancing effects of captafol on the development of GST-P-positive liver cell foci in a medium-term bioassay, and protection by L-cysteine of the enhancement in rats. Cancer letters. 1997 Jan; 111(1-2):15-20. doi: 10.1016/s0304-3835(96)04483-7. [PMID: 9022123]
  • M A Rodrigues, M D'Angelo. Cytotoxicity of captafol in mammalian cells. Biomedical and environmental sciences : BES. 1994 Sep; 7(3):278-83. doi: NULL. [PMID: 7531451]
  • J A Quest, P A Fenner-Crisp, W Burnam, M Copley, K L Dearfield, K L Hamernik, D S Saunders, R J Whiting, R Engler. Evaluation of the carcinogenic potential of pesticides. 4. Chloroalkylthiodicarboximide compounds with fungicidal activity. Regulatory toxicology and pharmacology : RTP. 1993 Feb; 17(1):19-34. doi: 10.1006/rtph.1993.1003. [PMID: 8441825]
  • S Tamano, Y Kurata, M Shibata, H Tanaka, T Ogiso, N Ito. 13-Week oral toxicity study of captafol in F344/DuCrj rats. Fundamental and applied toxicology : official journal of the Society of Toxicology. 1991 Aug; 17(2):390-8. doi: 10.1016/0272-0590(91)90228-v. [PMID: 1765226]
  • G Garcia, J Kirchhoff, F Grossmann. [Formation and degradation of triademinol after the use of triadimefon in a wheat monoculture]. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1991 Aug; 26(4):427-36. doi: 10.1080/03601239109372746. [PMID: 1787262]
  • S Tamano, Y Kurata, M Kawabe, A Yamamoto, A Hagiwara, R Cabral, N Ito. Carcinogenicity of captafol in F344/DuCrj rats. Japanese journal of cancer research : Gann. 1990 Dec; 81(12):1222-31. doi: 10.1111/j.1349-7006.1990.tb02683.x. [PMID: 2125991]
  • J E Garcia-G, J Kirchhoff, F Grossmann. [Behavior of captafol residues after prolonged application in a wheat monoculture]. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 1990 Apr; 25(2):185-204. doi: 10.1080/10934529009375549. [PMID: 2380486]
  • A Nyska, T Waner, M Pirak, E Gordon, P Bracha, B Klein. The renal carcinogenic effect of Merpafol in the Fischer 344 rat. Israel journal of medical sciences. 1989 Aug; 25(8):428-32. doi: NULL. [PMID: 2767949]
  • B Büttler, W D Hörmann. High-pressure liquid chromatographic determination of captan, captafol, and folpet residues in plant material. Journal of agricultural and food chemistry. 1981 Mar; 29(2):257-60. doi: 10.1021/jf00104a012. [PMID: 7229209]
  • J C Stoke. Captafol dermatitis in the timber industry. Contact dermatitis. 1979 Sep; 5(5):284-92. doi: 10.1111/j.1600-0536.1979.tb04880.x. [PMID: 159800]