Reaction Process: PharmGKB:PA166246401

Aripiprazole Pathway, Pharmacokinetics related metabolites

find 1 related metabolites which is associated with chemical reaction(pathway) Aripiprazole Pathway, Pharmacokinetics

N-hydroxymethyl aripiprazole ⟶ aripiprazole + formaldehyde

Dehydroaripiprazole

7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one

C23H25Cl2N3O2 (445.1324)


Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole. Dehydroaripiprazole has with antipsychotic activity equivalent to Aripiprazole[1][2][3].