Reaction Process: PharmGKB:PA166179273

Metoprolol Pathway, Pharmacokinetics related metabolites

find 3 related metabolites which is associated with chemical reaction(pathway) Metoprolol Pathway, Pharmacokinetics

metoprolol ⟶ N-desisopropyl metoprolol

O-Demethylmetoprolol

O-Desmethyl Metoprolol

C14H23NO3 (253.1677848)


   

alpha-Hydroxymetoprolol

1-[4-(1-hydroxy-2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol

C15H25NO4 (283.178349)


alpha-Hydroxymetoprolol is a metabolite of metoprolol. Metoprolol is a selective β1 receptor blocker used in treatment of several diseases of the cardiovascular system, especially hypertension. The active substance metoprolol is employed either as metoprolol succinate or metoprolol tartrate (where 100 mg metoprolol tartrate corresponds to 95 mg metoprolol succinate). The tartrate is an immediate-release and the succinate is an extended-release formulation. (Wikipedia)

   

Metoprolol acid

2-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)acetic acid

C14H21NO4 (267.1470506)