NCBI Taxonomy: 98688

Packera aurea (ncbi_taxid: 98688)

found 40 associated metabolites at species taxonomy rank level.

Ancestor: Packera

Child Taxonomies: none taxonomy data.

Senecionine

(1,6)Dioxacyclododecino(2,3,4-gh)pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-5,6-dimethyl-, (3Z,5R,6R,14aR,14bR)-

C18H25NO5 (335.173264)


Senecionine is a pyrrolizidine alkaloid isolated from the plant species of the genus Senecio. It has a role as a plant metabolite. It is a lactone, a pyrrolizidine alkaloid and a tertiary alcohol. It is functionally related to a senecionan. It is a conjugate base of a senecionine(1+). Senecionine is a natural product found in Dorobaea pimpinellifolia, Crotalaria micans, and other organisms with data available. Senecionine is an organic compound with the chemical formula C18H25NO5. It is classified as a pyrrolizidine alkaloid. See also: Petasites hybridus root (part of); Tussilago farfara flower (part of); Tussilago farfara leaf (part of). A pyrrolizidine alkaloid isolated from the plant species of the genus Senecio. D000970 - Antineoplastic Agents Annotation level-1 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2251 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 122 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 102 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 142 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 152 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 162 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 172 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 132 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 112 [Raw Data] CB082a_Senecionine_pos_40eV_CB000034.txt [Raw Data] CB082a_Senecionine_pos_10eV_CB000034.txt [Raw Data] CB082a_Senecionine_pos_30eV_CB000034.txt [Raw Data] CB082a_Senecionine_pos_20eV_CB000034.txt [Raw Data] CB082a_Senecionine_pos_50eV_CB000034.txt Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH)[1][2][3]. Senecionine (Senecionan-11,16-dione, 12-hydroxy-) is a pyrrolizidine alkaloid could be isolated from Senecio vulgaris. Senecionine decreases the activities of glutathione S-transferase, aminopyrine demethylase and arylhydrocarbon hydroxylase (AHH)[1][2][3].

   

Eremophilenolide

Tetrahydroligularenolide

C15H22O2 (234.1619712)


   

Integerrimine

4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione

C18H25NO5 (335.173264)


   

Dehydrofukinone

(4aR,5S)-4a,5-dimethyl-3-(propan-2-ylidene)-2,3,4,4a,5,6,7,8-octahydronaphthalen-2-one

C15H22O (218.1670562)


Dehydrofukinone is a member of the class of compounds known as eremophilane, 8,9-secoeremophilane and furoeremophilane sesquiterpenoids. Eremophilane, 8,9-secoeremophilane and furoeremophilane sesquiterpenoids are sesquiterpenoids with a structure based either on the eremophilane skeleton, its 8,9-seco derivative, or the furoeremophilane skeleton. Eremophilanes have been shown to be derived from eudesmanes by migration of the methyl group at C-10 to C-5. Dehydrofukinone is practically insoluble (in water) and an extremely weak acidic compound (based on its pKa). Dehydrofukinone can be found in burdock, which makes dehydrofukinone a potential biomarker for the consumption of this food product.

   

Otosenine

Otosenine

C19H27NO7 (381.1787432)


relative retention time with respect to 9-anthracene Carboxylic Acid is 0.260 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.248

   

(1R,3S,4S,6R,7R,11Z)-3,6,7,14-tetramethyl-3,8,17-trioxospiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2-oxiran]-7-yl acetate

(1R,3S,4S,6R,7R,11Z)-3,6,7,14-tetramethyl-3,8,17-trioxospiro[2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-4,2-oxiran]-7-yl acetate

C21H29NO8 (423.1893074)


   

(4ar,5s,8as,9ar)-3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah,9h,9ah-naphtho[2,3-b]furan-2-one

(4ar,5s,8as,9ar)-3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah,9h,9ah-naphtho[2,3-b]furan-2-one

C15H22O2 (234.1619712)


   

(4ar,5s)-3,4a,5-trimethyl-4h,5h,6h,7h-naphtho[2,3-b]furan-2-one

(4ar,5s)-3,4a,5-trimethyl-4h,5h,6h,7h-naphtho[2,3-b]furan-2-one

C15H18O2 (230.1306728)


   

(4e)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione

(4e)-4-ethylidene-7-hydroxy-6,7-dimethyl-2,9-dioxa-14-azatricyclo[9.5.1.0¹⁴,¹⁷]heptadec-11-ene-3,8-dione

C18H25NO5 (335.173264)


   

(1r,3's,4s,6r,7r,11z)-3',6,7,14-tetramethyl-3,8,17-trioxo-2,9-dioxa-14-azaspiro[bicyclo[9.5.1]heptadecane-4,2'-oxiran]-11-en-7-yl acetate

(1r,3's,4s,6r,7r,11z)-3',6,7,14-tetramethyl-3,8,17-trioxo-2,9-dioxa-14-azaspiro[bicyclo[9.5.1]heptadecane-4,2'-oxiran]-11-en-7-yl acetate

C21H29NO8 (423.1893074)


   

(4ar,5s,8as,9ar)-9a-ethoxy-3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah,9h-naphtho[2,3-b]furan-2-one

(4ar,5s,8as,9ar)-9a-ethoxy-3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah,9h-naphtho[2,3-b]furan-2-one

C17H26O3 (278.1881846)


   

4a,5-dimethyl-3-(propan-2-ylidene)-5,6,7,8-tetrahydro-4h-naphthalen-2-one

4a,5-dimethyl-3-(propan-2-ylidene)-5,6,7,8-tetrahydro-4h-naphthalen-2-one

C15H22O (218.1670562)


   

3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah-naphtho[2,3-b]furan-9-one

3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah-naphtho[2,3-b]furan-9-one

C15H20O2 (232.14632200000003)


   

(4ar,5s,8ar)-3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah-naphtho[2,3-b]furan-9-one

(4ar,5s,8ar)-3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah-naphtho[2,3-b]furan-9-one

C15H20O2 (232.14632200000003)


   

3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah,9h,9ah-naphtho[2,3-b]furan-2-one

3,4a,5-trimethyl-4h,5h,6h,7h,8h,8ah,9h,9ah-naphtho[2,3-b]furan-2-one

C15H22O2 (234.1619712)


   

(4s,6r,7r,11z)-4-hydroxy-4-[(1s)-1-hydroxyethyl]-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

(4s,6r,7r,11z)-4-hydroxy-4-[(1s)-1-hydroxyethyl]-6,7,14-trimethyl-3,8,17-trioxo-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-en-7-yl acetate

C21H31NO9 (441.19987160000005)


   

(1r,3's,6r,7r,11z)-3',6,7,14-tetramethyl-3,8,17-trioxo-2,9-dioxa-14-azaspiro[bicyclo[9.5.1]heptadecane-4,2'-oxiran]-11-en-7-yl acetate

(1r,3's,6r,7r,11z)-3',6,7,14-tetramethyl-3,8,17-trioxo-2,9-dioxa-14-azaspiro[bicyclo[9.5.1]heptadecane-4,2'-oxiran]-11-en-7-yl acetate

C21H29NO8 (423.1893074)