NCBI Taxonomy: 867468
Pilosocereus (ncbi_taxid: 867468)
found 15 associated metabolites at genus taxonomy rank level.
Ancestor: Echinocereeae
Child Taxonomies: Pilosocereus ulei, Pilosocereus rosae, Pilosocereus hermii, Pilosocereus parvus, Pilosocereus bohlei, Pilosocereus alensis, Pilosocereus royenii, Pilosocereus gaumeri, Pilosocereus robinii, Pilosocereus purpusii, Pilosocereus floccosus, Pilosocereus aurisetus, Pilosocereus azulensis, Pilosocereus collinsii, Pilosocereus arrabidae, Pilosocereus machrisii, Pilosocereus polygonus, Pilosocereus diersianus, Pilosocereus albisummus, Pilosocereus magnificus, Pilosocereus splendidus, Pilosocereus juaruensis, Pilosocereus oligolepis, Pilosocereus aurilanatus, Pilosocereus aureispinus, Pilosocereus vilaboensis, Pilosocereus mollispinus, Pilosocereus pachycladus, Pilosocereus catingicola, Pilosocereus chrysostele, Pilosocereus brooksianus, Pilosocereus moritzianus, Pilosocereus lanuginosus, Pilosocereus piauhyensis, unclassified Pilosocereus, Pilosocereus brasiliensis, Pilosocereus fulvilanatus, Pilosocereus glaucochrous, Pilosocereus millspaughii, Pilosocereus chrysacanthus, Pilosocereus leucocephalus, Pilosocereus multicostatus, Pilosocereus densiareolatus, Pilosocereus flexibilispinus, Pilosocereus flavipulvinatus, Pilosocereus pentaedrophorus, Pilosocereus pusillibaccatus, Pilosocereus quadricentralis, Pilosocereus aff. alensis T1589
3,4-Dimethoxyphenylethylamine
3,4-Dimethoxyphenylethylamine, also known as 3,4-DMPEA or DMPEA is an endogenous metabolite found in urine that belongs to both the phenethylamine and catecholamine families. DMPEA is an analogue of dopamine (3,4-dihydroxyphenethylamine), with a substitution of the hydroxy groups with methoxy groups. DMPEA is also structurally similar to mescaline (3,4,5-trimethoxyphenylethylamine) and occurs naturally alongside it in various species of cacti such as the San Pedro and Peruvian Torch (PMID: 5511715, 925910, 600028). DMPEA received wide attention after it was proposed as a biomarker in schizophrenic patients urine, however later studies revealed that DMPEA is also excreted by non-schizophrenics (PMID: 709888). DMPEA has little known bioactivity, but it has some action as a monoamine oxidase inhibitor (PMID: 886445). DMPEA has also been shown to have neurotoxic effects, especially in the nigrostriatal system and among dopaminergic neurons (PMID: 9409711, 9134983). DMPEA appears to be an inhibitor of mitochondrial complex I (PMID: 9409711).