12(S)-HPETE

(5Z,8Z,10E,14Z)-(12S)-12-Hydroperoxyeicosa-5,8,10,14-tetraenoic acid

C20H32O4 (336.2300472)


12-HPETE is one of the six monohydroperoxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid (Leukotrienes). Reduction of the hydroperoxide yields the more stable hydroxyl fatty acid (+/-)12-HETE. A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system. 12-HPETE is one of the six monohydroperoxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid (Leukotrienes). Reduction of the hydroperoxide yields the more stable hydroxyl fatty acid (+/-)12-HETE. D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents

   

12-Hydroperoxy-icosatetraenoic acid

12-hydroperoxyicosa-2,4,6,8-tetraenoic acid

C20H32O4 (336.2300472)


   

12(S)-HPETE

12-Hydroperoxy-5,8,10,14-eicosatetraenoic acid

C20H32O4 (336.2300472)


D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents The (S)-enantiomer of 12-HPETE.

   

11-hydroperoxyicosa-2,4,6,8-tetraenoic acid

11-hydroperoxyicosa-2,4,6,8-tetraenoic acid

C20H32O4 (336.2300472)


   

9-hydroperoxyicosa-2,4,6,8-tetraenoic acid

9-hydroperoxyicosa-2,4,6,8-tetraenoic acid

C20H32O4 (336.2300472)