NCBI Taxonomy: 316863

Spirostachys africana (ncbi_taxid: 316863)

found 27 associated metabolites at species taxonomy rank level.

Ancestor: Spirostachys

Child Taxonomies: none taxonomy data.

Lupeol

(1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol

C30H50O (426.3861)


Lupeol is a pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in many edible fruits and vegetables. It has a role as an anti-inflammatory drug and a plant metabolite. It is a secondary alcohol and a pentacyclic triterpenoid. It derives from a hydride of a lupane. Lupeol has been investigated for the treatment of Acne. Lupeol is a natural product found in Ficus auriculata, Ficus septica, and other organisms with data available. See also: Calendula Officinalis Flower (part of). A pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in many edible fruits and vegetables. D000893 - Anti-Inflammatory Agents Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1]. Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1].

   

(+/-)-2-Hydroxypiperitone

2-hydroxy-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-one

C10H16O2 (168.115)


(+/-)-2-hydroxypiperitone, also known as 2-hydroxy-6-isopropyl-3-methyl-2-cyclohexen-1-one or barosma camphor, is a member of the class of compounds known as menthane monoterpenoids. Menthane monoterpenoids are monoterpenoids with a structure based on the o-, m-, or p-menthane backbone. P-menthane consists of the cyclohexane ring with a methyl group and a (2-methyl)-propyl group at the 1 and 4 ring position, respectively. The o- and m- menthanes are much rarer, and presumably arise by alkyl migration of p-menthanes. Thus, (+/-)-2-hydroxypiperitone is considered to be an isoprenoid lipid molecule (+/-)-2-hydroxypiperitone is slightly soluble (in water) and a very weakly acidic compound (based on its pKa). (+/-)-2-hydroxypiperitone is a blackcurrant, buchu, and leaves tasting compound found in blackcurrant, peppermint, and spearmint, which makes (+/-)-2-hydroxypiperitone a potential biomarker for the consumption of these food products.

   

lupeol

Lup-20(29)-en-3.beta.-ol

C30H50O (426.3861)


D000893 - Anti-Inflammatory Agents Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1]. Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic?triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent?androgen receptor (AR)?inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC)[1].

   

Diosphenol

2-hydroxy-3-methyl-6-(propan-2-yl)cyclohex-2-en-1-one

C10H16O2 (168.115)


A cyclic monoterpene ketone that is cyclohex-2-en-1-one substituted by a hydroxy group at position 2, a methyl group at position 3 and an isopropyl group at position 6.

   

acetyl aleuritolic acid

(4aS,6aR,6bR,8aR,10S,12aR,14aS,14bS)-10-acetyloxy-2,2,6b,9,9,12a,14a-heptamethyl-1,3,4,5,6a,7,8,8a,10,11,12,13,14,14b-tetradecahydropicene-4a-carboxylic acid

C32H50O4 (498.3709)


A pentacyclic triterpenoid isolated from the leaves of Garcia parviflora.

   

6-hydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-ene-7,12-dione

6-hydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-ene-7,12-dione

C19H26O3 (302.1882)


   

7-hydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

7-hydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

C19H24O2 (284.1776)


   

2-[(1s,4r,5s,6s)-5-(carboxymethyl)-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-4-yl]-2-methylpropanoic acid

2-[(1s,4r,5s,6s)-5-(carboxymethyl)-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-4-yl]-2-methylpropanoic acid

C20H30O4 (334.2144)


   

2-[(1s,4r,5s,6s,9s)-5-(carboxymethyl)-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-4-yl]-2-methylpropanoic acid

2-[(1s,4r,5s,6s,9s)-5-(carboxymethyl)-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-4-yl]-2-methylpropanoic acid

C20H30O4 (334.2144)


   

(1r,4s,5s,6s,9s,10s,13s)-6-hydroxy-5-(hydroxymethyl)-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-7-one

(1r,4s,5s,6s,9s,10s,13s)-6-hydroxy-5-(hydroxymethyl)-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-7-one

C20H30O3 (318.2195)


   

6-hydroxy-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-7-one

6-hydroxy-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-7-one

C20H30O2 (302.2246)


   

2-[5-(carboxymethyl)-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-4-yl]-2-methylpropanoic acid

2-[5-(carboxymethyl)-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-4-yl]-2-methylpropanoic acid

C20H30O4 (334.2144)


   

(1s,3r,9r,10r,13s)-3,7-dihydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

(1s,3r,9r,10r,13s)-3,7-dihydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

C19H24O3 (300.1725)


   

6-hydroxy-5-(hydroxymethyl)-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-7-one

6-hydroxy-5-(hydroxymethyl)-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-7-one

C20H30O3 (318.2195)


   

3,7-dihydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

3,7-dihydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

C19H24O3 (300.1725)


   

(1r,4r,5r,6s,9r,10s,13s)-6-hydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-ene-7,12-dione

(1r,4r,5r,6s,9r,10s,13s)-6-hydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-ene-7,12-dione

C19H26O3 (302.1882)


   

(1s,3s,9r,10r,13s)-3,7-dihydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

(1s,3s,9r,10r,13s)-3,7-dihydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

C19H24O3 (300.1725)


   

2-[(1r,4s,5s,6s,9s)-5-(carboxymethyl)-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-4-yl]-2-methylpropanoic acid

2-[(1r,4s,5s,6s,9s)-5-(carboxymethyl)-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-4-yl]-2-methylpropanoic acid

C20H30O4 (334.2144)


   

5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-ol

5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-ol

C20H32O (288.2453)


   

{4-acetyl-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-5-yl}acetic acid

{4-acetyl-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-5-yl}acetic acid

C18H26O3 (290.1882)


   

(1r,4s,6s,9s,10s,13s)-6-hydroxy-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-7-one

(1r,4s,6s,9s,10s,13s)-6-hydroxy-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-7-one

C20H30O2 (302.2246)


   

(1r,4s,9s,10s,13s)-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-one

(1r,4s,9s,10s,13s)-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-one

C20H30O (286.2297)


   

[(1r,4s,5s,6s,9s)-4-acetyl-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-5-yl]acetic acid

[(1r,4s,5s,6s,9s)-4-acetyl-5,9-dimethyltricyclo[7.2.1.0¹,⁶]dodec-10-en-5-yl]acetic acid

C18H26O3 (290.1882)


   

(1r,4s,6r,9s,10s,13s)-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-ol

(1r,4s,6r,9s,10s,13s)-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-ol

C20H32O (288.2453)


   

(1s,4s,6r,9s,10s,13r)-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-ol

(1s,4s,6r,9s,10s,13r)-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-ol

C20H32O (288.2453)


   

(1r,9r,10r,13s)-7-hydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

(1r,9r,10r,13s)-7-hydroxy-5,9,13-trimethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadeca-4,7,14-trien-6-one

C19H24O2 (284.1776)


   

(1r,4s,6s,9s,10s,13s)-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-ol

(1r,4s,6s,9s,10s,13s)-5,5,9,13-tetramethyltetracyclo[11.2.1.0¹,¹⁰.0⁴,⁹]hexadec-14-en-6-ol

C20H32O (288.2453)