NCBI Taxonomy: 314506

Campanularia (ncbi_taxid: 314506)

found 12 associated metabolites at genus taxonomy rank level.

Ancestor: Campanulariidae

Child Taxonomies: Campanularia hincksii, Campanularia volubilis, Campanularia tulipifera, Campanularia lennoxensis, unclassified Campanularia

Vorinostat

Octanedioic acid hydroxyamide phenylamide

C14H20N2O3 (264.147385)


Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first in a new class of agents known as histone deacetylase inhibitors. A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4 - 4.4 months in earlier studies). Further brain tumor trials are planned in which vorinostat will be combined with other drugs. [Wikipedia] L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01X - Other antineoplastic agents > L01XH - Histone deacetylase (hdac) inhibitors D004791 - Enzyme Inhibitors > D056572 - Histone Deacetylase Inhibitors C471 - Enzyme Inhibitor > C1946 - Histone Deacetylase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent D000970 - Antineoplastic Agents

   

Isorhynchospermin

3,5,3-Trihydroxy-7,4-dimethoxy-6-prenylflavone

C22H22O7 (398.1365462)


   

Vorinostat

N1-hydroxy-N8-phenyl-octanediamide

C14H20N2O3 (264.147385)


L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01X - Other antineoplastic agents > L01XH - Histone deacetylase (hdac) inhibitors D004791 - Enzyme Inhibitors > D056572 - Histone Deacetylase Inhibitors C471 - Enzyme Inhibitor > C1946 - Histone Deacetylase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent D000970 - Antineoplastic Agents

   

(2r,3r)-3,5-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-1-benzopyran-4-one

(2r,3r)-3,5-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-1-benzopyran-4-one

C22H24O7 (400.1521954)


   

(5-hydroxy-3-{[(2s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3s,5r)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-2-(3,4,5-trihydroxyphenyl)chromen-7-ylidene)[(2s,4s,5s)-3,4,5-trihydroxy-6-[(4-{[(2s,4s,5s)-3,4,5-trihydroxy-6-{[hydroxy(4-oxocyclohexa-2,5-dien-1-ylidene)methoxy]methyl}oxan-2-yl]oxy}benzoyloxy)methyl]oxan-2-yl]oxidanium

(5-hydroxy-3-{[(2s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3s,5r)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-2-(3,4,5-trihydroxyphenyl)chromen-7-ylidene)[(2s,4s,5s)-3,4,5-trihydroxy-6-[(4-{[(2s,4s,5s)-3,4,5-trihydroxy-6-{[hydroxy(4-oxocyclohexa-2,5-dien-1-ylidene)methoxy]methyl}oxan-2-yl]oxy}benzoyloxy)methyl]oxan-2-yl]oxidanium

[C53H59O30]+ (1175.3091014000001)


   

(5-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-2-(3,4,5-trihydroxyphenyl)chromen-7-ylidene)[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[(4-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-{[hydroxy(4-oxocyclohexa-2,5-dien-1-ylidene)methoxy]methyl}oxan-2-yl]oxy}benzoyloxy)methyl]oxan-2-yl]oxidanium

(5-hydroxy-3-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-2-(3,4,5-trihydroxyphenyl)chromen-7-ylidene)[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[(4-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-{[hydroxy(4-oxocyclohexa-2,5-dien-1-ylidene)methoxy]methyl}oxan-2-yl]oxy}benzoyloxy)methyl]oxan-2-yl]oxidanium

[C53H59O30]+ (1175.3091014000001)