NCBI Taxonomy: 283120

Flueggea suffruticosa (ncbi_taxid: 283120)

found 83 associated metabolites at species taxonomy rank level.

Ancestor: Flueggea

Child Taxonomies: none taxonomy data.

Securinine

6,10-METHANOPYRIDO(1,2-A)AZEPINE-.GAMMA.9(6H),.ALPHA.-ACETIC ACID,1,2,3,4,10,10A-HEXAHYDRO-10-HYDROXY-, .GAMMA.-LACTONE

C13H15NO2 (217.110273)


Securinine is a member of indolizines. Securinine is a natural product found in Flueggea suffruticosa, Flueggea virosa, and other organisms with data available. See also: Phyllanthus amarus top (part of). relative retention time with respect to 9-anthracene Carboxylic Acid is 0.053 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.052 (-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist. (-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist. (-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist. (-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist. (-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist. (-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist. Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from Phyllanthus glaucus [1].

   

1-(7-hydroxy-2,6-dimethyl-1-naphthyl)-4-methyl-3-pentanone

1-(7-hydroxy-2,6-dimethyl-1-naphthyl)-4-methyl-3-pentanone

C18H22O2 (270.1619712)


   

3beta,12-Dihydroxy-13-methyl-5,8,11,13-podocarpatetraene-7-one

3beta,12-Dihydroxy-13-methyl-5,8,11,13-podocarpatetraene-7-one

C18H22O3 (286.15688620000003)


A diterpenoid that is podocarpa-5,8,11,13-tetraen-7-one substituted by hydroxy groups at positions 3 and 12 and a methyl group at position 13 (the 3beta stereoisomer). Isolated from Securinega suffruticosa, it exhibits antineoplastic activity.

   

3beta,12-Dihydroxy-13-methyl-6,8,11,13-podocarpatetraene

3beta,12-Dihydroxy-13-methyl-6,8,11,13-podocarpatetraene

C18H24O2 (272.17762039999997)


A diterpenoid that is podocarpa-6,8,11,13-tetraene substituted by a methyl group at position 13 and hydroxy groups at position 3 and 12. Isolated from Securinega suffruticosa, it exhibits cytotoxicity towards human cancer cells.

   

(1s,2s,4s,8s)-4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

(1s,2s,4s,8s)-4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

C14H17NO3 (247.1208372)


   

(1s,2s,4s,8s,9s)-4,9-dimethoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

(1s,2s,4s,8s,9s)-4,9-dimethoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

C15H21NO4 (279.1470506)


   

(1s,2s,8s,9s)-9-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

(1s,2s,8s,9s)-9-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

C14H19NO3 (249.1364864)


   

4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

C14H17NO3 (247.1208372)


   

(1r,2r,8r)-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

(1r,2r,8r)-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

C13H15NO2 (217.110273)


   

(1s,2s,3r,8s)-2-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0³,⁷]pentadeca-9,11-dien-13-one

(1s,2s,3r,8s)-2-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0³,⁷]pentadeca-9,11-dien-13-one

C13H15NO3 (233.105188)


   

(1s,2s,8r,15r)-15-hydroxy-11-[(2s)-piperidin-2-yl]-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

(1s,2s,8r,15r)-15-hydroxy-11-[(2s)-piperidin-2-yl]-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

C18H26N2O3 (318.19433260000005)


   

(9r)-9-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

(9r)-9-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

C13H17NO3 (235.1208372)


   

(1s,2s,9s)-8,15-dioxa-7-azatetracyclo[7.6.1.0¹,¹².0²,⁷]hexadeca-10,12-dien-14-one

(1s,2s,9s)-8,15-dioxa-7-azatetracyclo[7.6.1.0¹,¹².0²,⁷]hexadeca-10,12-dien-14-one

C13H15NO3 (233.105188)


   

(4s)-4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

(4s)-4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

C14H17NO3 (247.1208372)


   

1,1,4a,7-tetramethyl-2,3,4,10a-tetrahydrophenanthrene-2,6-diol

1,1,4a,7-tetramethyl-2,3,4,10a-tetrahydrophenanthrene-2,6-diol

C18H24O2 (272.17762039999997)


   

15-hydroxy-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

15-hydroxy-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

C13H17NO3 (235.1208372)


   

(2s,4as)-2,6-dihydroxy-1,1,4a,7-tetramethyl-3,4-dihydro-2h-phenanthren-9-one

(2s,4as)-2,6-dihydroxy-1,1,4a,7-tetramethyl-3,4-dihydro-2h-phenanthren-9-one

C18H22O3 (286.15688620000003)


   

(1r,2r,8s,15r)-15-hydroxy-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

(1r,2r,8s,15r)-15-hydroxy-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

C13H17NO3 (235.1208372)


   

14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

C13H15NO2 (217.110273)


   

(1s,2s)-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

(1s,2s)-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

C13H15NO2 (217.110273)


   

2-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0³,⁷]pentadeca-9,11-dien-13-one

2-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0³,⁷]pentadeca-9,11-dien-13-one

C13H15NO3 (233.105188)


   

4-methoxy-8,15-dioxa-7-azatetracyclo[7.6.1.0¹,¹².0²,⁷]hexadeca-10,12-dien-14-one

4-methoxy-8,15-dioxa-7-azatetracyclo[7.6.1.0¹,¹².0²,⁷]hexadeca-10,12-dien-14-one

C14H17NO4 (263.11575220000003)


   

4,9-dimethoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

4,9-dimethoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

C15H21NO4 (279.1470506)


   

1-(7-hydroxy-2,6-dimethylnaphthalen-1-yl)-4-methylpentan-3-one

1-(7-hydroxy-2,6-dimethylnaphthalen-1-yl)-4-methylpentan-3-one

C18H22O2 (270.1619712)


   

15-(diethylamino)-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

15-(diethylamino)-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

C17H26N2O2 (290.1994176)


   

(1s,2r,8s,9s)-9-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

(1s,2r,8s,9s)-9-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

C14H19NO3 (249.1364864)


   

(1s,2s,4s,9s)-4-methoxy-8,15-dioxa-7-azatetracyclo[7.6.1.0¹,¹².0²,⁷]hexadeca-10,12-dien-14-one

(1s,2s,4s,9s)-4-methoxy-8,15-dioxa-7-azatetracyclo[7.6.1.0¹,¹².0²,⁷]hexadeca-10,12-dien-14-one

C14H17NO4 (263.11575220000003)


   

15-hydroxy-11-(piperidin-2-yl)-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

15-hydroxy-11-(piperidin-2-yl)-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

C18H26N2O3 (318.19433260000005)


   

2,6-dihydroxy-1,1,4a,7-tetramethyl-3,4-dihydro-2h-phenanthren-9-one

2,6-dihydroxy-1,1,4a,7-tetramethyl-3,4-dihydro-2h-phenanthren-9-one

C18H22O3 (286.15688620000003)


   

(2s,4as,10ar)-1,1,4a,7-tetramethyl-2,3,4,10a-tetrahydrophenanthrene-2,6-diol

(2s,4as,10ar)-1,1,4a,7-tetramethyl-2,3,4,10a-tetrahydrophenanthrene-2,6-diol

C18H24O2 (272.17762039999997)


   

8,15-dioxa-7-azatetracyclo[7.6.1.0¹,¹².0²,⁷]hexadeca-10,12-dien-14-one

8,15-dioxa-7-azatetracyclo[7.6.1.0¹,¹².0²,⁷]hexadeca-10,12-dien-14-one

C13H15NO3 (233.105188)


   

(1r,2s,8s,15r)-15-(diethylamino)-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

(1r,2s,8s,15r)-15-(diethylamino)-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

C17H26N2O2 (290.1994176)


   

(1s,2s,8r,15r)-15-hydroxy-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

(1s,2s,8r,15r)-15-hydroxy-13-oxa-7-azatetracyclo[6.5.2.0¹,¹⁰.0²,⁷]pentadec-10-en-12-one

C13H17NO3 (235.1208372)


   

(1s,2r,4s,8s)-4-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

(1s,2r,4s,8s)-4-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

C13H15NO3 (233.105188)


   

(1s,2r,3r,8s)-2-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0³,⁷]pentadeca-9,11-dien-13-one

(1s,2r,3r,8s)-2-hydroxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0³,⁷]pentadeca-9,11-dien-13-one

C13H15NO3 (233.105188)


   

9-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

9-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadec-11-en-13-one

C14H19NO3 (249.1364864)


   

(1s,2r,4s,8s)-4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

(1s,2r,4s,8s)-4-methoxy-14-oxa-7-azatetracyclo[6.6.1.0¹,¹¹.0²,⁷]pentadeca-9,11-dien-13-one

C14H17NO3 (247.1208372)