NCBI Taxonomy: 259380

Blighia (ncbi_taxid: 259380)

found 85 associated metabolites at genus taxonomy rank level.

Ancestor: Sapindaceae

Child Taxonomies: Blighia sapida, Blighia unijugata, Blighia welwitschii

Hypoglycin B

2-Amino-4-{[1-carboxy-2-(2-methylidenecyclopropyl)ethyl]-C-hydroxycarbonimidoyl}butanoate

C12H18N2O5 (270.1215658)


Hypoglycin B is found in fruits. Hypoglycin B is a biologically active component of Blighia sapida (akee apple) Hypoglycin B is a naturally occurring organic compound in the species Blighia sapida. It is particularly concentrated in the fruit of the plant especially in the seeds. Hypoglycin B is toxic if ingested and is a causative agent of Jamaican Vomiting Sickness. It is an amino acid and chemically related to lysine Biologically active component of Blighia sapida (akee apple)

   

Hederagenin

10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid

C30H48O4 (472.3552408)


Hederagenin is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Hederagenin is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Hederagenin can be found in a number of food items such as rye, dill, european cranberry, and black salsify, which makes hederagenin a potential biomarker for the consumption of these food products. Hederagenin is the aglycone part of numerous saponins found in Hedera helix (common ivy). The most prevalent of these being hederacoside C and alpha-hederin. It is also one of three primary triterpenoids extracted from the Chenopodium quinoa plant categorized by the EPA as a biopesticide. HeadsUp Plant Protectant is made up of approximately equal ratios of the saponin aglycones oleanolic acid, hederagenin, and phytolaccagenic acid and is intended for use as a seed treatment on tuber (e.g. potato seed pieces), legume, and cereal seeds or as a pre-plant root dip for roots of transplants, at planting, to prevent fungal growth, bacterial growth, and viral plant diseases .

   

Hederagenin

(4AS,6AS,6BR,8AR,9R,10S,12AR,12BR,14BS)-10-HYDROXY-9-(HYDROXYMETHYL)-2,2,6A,6B,9,12A-HEXAMETHYL-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-ICOSAHYDROPICENE-4A-CARBOXYLIC ACID

C30H48O4 (472.3552408)


Hederagenin is a sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer). It has a role as a plant metabolite. It is a pentacyclic triterpenoid, a dihydroxy monocarboxylic acid and a sapogenin. It is functionally related to an oleanolic acid. It is a conjugate acid of a hederagenin(1-). It derives from a hydride of an oleanane. Hederagenin is a natural product found in Zygophyllum obliquum, Sapindus emarginatus, and other organisms with data available. See also: Paeonia lactiflora root (part of); Caulophyllum robustum Root (part of); Medicago sativa whole (part of). A sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer). Hederagenin is a triterpenoid saponin that can inhibit the expression of iNOS, COX-2, and NF-κB in cells caused by LPS stimulation. Hederagenin is a triterpenoid saponin that can inhibit the expression of iNOS, COX-2, and NF-κB in cells caused by LPS stimulation.

   

L-CCG-I

2-[amino(carboxy)methyl]cyclopropane-1-carboxylic acid

C6H9NO4 (159.0531554)


D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018690 - Excitatory Amino Acid Agonists

   

gly-d-ala

Glycyl-D-Alanine

C5H10N2O3 (146.069139)


   

2-amino-3-(2-methylidenecyclopropyl)propanoic acid

2-amino-3-(2-methylidenecyclopropyl)propanoic acid

C7H11NO2 (141.0789746)


   

Hypoglycin a

Hypoglycin a

C7H11NO2 (141.0789746)


A diastereoisomeric mixture of (2S,4R)- and (2S,4S)- hypoglycin A, found in the edible part of the fruit of the Ackee, Blighia sapida (where the 2S,4R diastereoisomer is more dominant (17\\% d.e.) than its 2S,4S counterpart) as well as in the sycamore maple tree (Acer pseudoplatanus). D009676 - Noxae > D011042 - Poisons > D007005 - Hypoglycins

   

Hypoglycine b

(2S,4S)-hypoglycin B

C12H18N2O5 (270.1215658)


An L-glutamyl amino acid that is (2S,4S)-hypoglycin A in which the amino group has been acylated by the gamma-carboxy group of L-glutamic acid.

   

Hypoglycine a

Hypoglycine a

C7H11NO2 (141.0789746)


D009676 - Noxae > D011042 - Poisons > D007005 - Hypoglycins

   

(2s)-2-amino-4-{[(1s)-1-carboxy-2-[(1s)-2-methylidenecyclopropyl]ethyl]-c-hydroxycarbonimidoyl}butanoic acid

(2s)-2-amino-4-{[(1s)-1-carboxy-2-[(1s)-2-methylidenecyclopropyl]ethyl]-c-hydroxycarbonimidoyl}butanoic acid

C12H18N2O5 (270.1215658)


   

(s)-amino[(1s,2r)-2-(carboxymethyl)cyclopropyl]acetic acid

(s)-amino[(1s,2r)-2-(carboxymethyl)cyclopropyl]acetic acid

C7H11NO4 (173.0688046)


   

[(2-amino-1-hydroxyethylidene)amino]acetic acid

[(2-amino-1-hydroxyethylidene)amino]acetic acid

C4H8N2O3 (132.05348980000002)


   

2-[(2-amino-1-hydroxyethylidene)amino]propanoic acid

2-[(2-amino-1-hydroxyethylidene)amino]propanoic acid

C5H10N2O3 (146.069139)


   

2-amino-6-hydroxy-5-methylhex-4-enoic acid

2-amino-6-hydroxy-5-methylhex-4-enoic acid

C7H13NO3 (159.0895388)


   

(2s)-2-amino-4-{[(1s)-1-carboxy-2-(2-methylidenecyclopropyl)ethyl]-c-hydroxycarbonimidoyl}butanoic acid

(2s)-2-amino-4-{[(1s)-1-carboxy-2-(2-methylidenecyclopropyl)ethyl]-c-hydroxycarbonimidoyl}butanoic acid

C12H18N2O5 (270.1215658)


   

(4as,6as,6br,8ar,9s,10r,12as,12bs,14br)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid

(4as,6as,6br,8ar,9s,10r,12as,12bs,14br)-10-hydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid

C30H48O4 (472.3552408)


   

(2s,4e)-2-amino-6-hydroxy-5-methylhex-4-enoic acid

(2s,4e)-2-amino-6-hydroxy-5-methylhex-4-enoic acid

C7H13NO3 (159.0895388)


   

2-[(2-{[cyclopropyl(hydroxy)methylidene]amino}-1-hydroxyethylidene)amino]pentanedioic acid

2-[(2-{[cyclopropyl(hydroxy)methylidene]amino}-1-hydroxyethylidene)amino]pentanedioic acid

C11H16N2O6 (272.1008316)


   

10-({3-[(4-{[5-({3,5-dihydroxy-4-[(3,4,5-trihydroxyoxan-2-yl)oxy]oxan-2-yl}oxy)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,5-dihydroxy-6-methyloxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl}oxy)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid

10-({3-[(4-{[5-({3,5-dihydroxy-4-[(3,4,5-trihydroxyoxan-2-yl)oxy]oxan-2-yl}oxy)-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,5-dihydroxy-6-methyloxan-2-yl)oxy]-4,5-dihydroxyoxan-2-yl}oxy)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid

C57H92O25 (1176.5927382)


   

(2r)-2-[(2-amino-1-hydroxyethylidene)amino]propanoic acid

(2r)-2-[(2-amino-1-hydroxyethylidene)amino]propanoic acid

C5H10N2O3 (146.069139)


   

(2r)-2-[(2-{[cyclopropyl(hydroxy)methylidene]amino}-1-hydroxyethylidene)amino]pentanedioic acid

(2r)-2-[(2-{[cyclopropyl(hydroxy)methylidene]amino}-1-hydroxyethylidene)amino]pentanedioic acid

C11H16N2O6 (272.1008316)


   

2-amino-4-{[1-carboxy-2-(2-methylidenecyclopropyl)ethyl]-c-hydroxycarbonimidoyl}butanoic acid

2-amino-4-{[1-carboxy-2-(2-methylidenecyclopropyl)ethyl]-c-hydroxycarbonimidoyl}butanoic acid

C12H18N2O5 (270.1215658)


   

({2-[(2-amino-1-hydroxyethylidene)amino]-1-hydroxyethylidene}amino)acetic acid

({2-[(2-amino-1-hydroxyethylidene)amino]-1-hydroxyethylidene}amino)acetic acid

C6H11N3O4 (189.0749526)


   

amino[2-(carboxymethyl)cyclopropyl]acetic acid

amino[2-(carboxymethyl)cyclopropyl]acetic acid

C7H11NO4 (173.0688046)


   

(4as,6as,6br,8as,9r,10s,12ar,12bs,14bs)-10-{[(2s,3r,4s,5s)-3-{[(2s,3r,4r,5s,6s)-4-{[(2s,3r,4r,5s,6r)-5-{[(2s,3r,4s,5s)-3,5-dihydroxy-4-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid

(4as,6as,6br,8as,9r,10s,12ar,12bs,14bs)-10-{[(2s,3r,4s,5s)-3-{[(2s,3r,4r,5s,6s)-4-{[(2s,3r,4r,5s,6r)-5-{[(2s,3r,4s,5s)-3,5-dihydroxy-4-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,7,8,8a,10,11,12,12b,13,14b-tetradecahydropicene-4a-carboxylic acid

C57H92O25 (1176.5927382)