NCBI Taxonomy: 171436

Tistrella (ncbi_taxid: 171436)

found 17 associated metabolites at genus taxonomy rank level.

Ancestor: Geminicoccaceae

Child Taxonomies: Tistrella mobilis, Tistrella bauzanensis, environmental samples, unclassified Tistrella

Didemnin B

Didemnin B

C57H89N7O15 (1111.6416324000002)


C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic A natural product found particularly in Lyngbya majuscula and Trididemnum solidum. D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C308 - Immunotherapeutic Agent > C574 - Immunosuppressant C784 - Protein Synthesis Inhibitor D000970 - Antineoplastic Agents Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer[1].

   

n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-8,11,18-trihydroxy-10,15-diisopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-8,11,18-trihydroxy-10,15-diisopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

C56H87N7O15 (1097.6259832)


   

(4s)-5-{[(2s)-1-[(2s)-2-{[(1r)-1-{[(3s,6s,7s,10s,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-c-hydroxycarbonimidoyl}-3-methylbutyl](methyl)carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]oxy}-4-{[(2s)-2-{[(2s)-2-{[(2s)-2-{[(3r)-1,3-dihydroxydecylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-5-oxopentanoic acid

(4s)-5-{[(2s)-1-[(2s)-2-{[(1r)-1-{[(3s,6s,7s,10s,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-c-hydroxycarbonimidoyl}-3-methylbutyl](methyl)carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]oxy}-4-{[(2s)-2-{[(2s)-2-{[(2s)-2-{[(3r)-1,3-dihydroxydecylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-5-oxopentanoic acid

C87H138N14O26 (1794.9906208)


   

2-{1-[1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-{8,11,18-trihydroxy-10,15-diisopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}pentanimidic acid

2-{1-[1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-{8,11,18-trihydroxy-10,15-diisopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}pentanimidic acid

C56H87N7O15 (1097.6259832)


   

(4s)-5-{[(2s)-1-[(2s)-2-{[(1r)-1-{[(3s,6s,7s,10s,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-c-hydroxycarbonimidoyl}-3-methylbutyl](methyl)carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]oxy}-4-{[(2s)-2-{[(2s)-2-{[(3r)-1,3-dihydroxydecylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-5-oxopentanoic acid

(4s)-5-{[(2s)-1-[(2s)-2-{[(1r)-1-{[(3s,6s,7s,10s,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-c-hydroxycarbonimidoyl}-3-methylbutyl](methyl)carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]oxy}-4-{[(2s)-2-{[(2s)-2-{[(3r)-1,3-dihydroxydecylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-1-hydroxy-4-(c-hydroxycarbonimidoyl)butylidene]amino}-5-oxopentanoic acid

C82H130N12O24 (1666.9320460000001)


   

(2r)-n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

(2r)-n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

C57H89N7O15 (1111.6416324000002)