NCBI Taxonomy: 119900

Memecylon (ncbi_taxid: 119900)

found 6 associated metabolites at genus taxonomy rank level.

Ancestor: Olisbeoideae

Child Taxonomies: Memecylon edule, Memecylon durum, Memecylon ovatum, Memecylon roseum, Memecylon grande, Memecylon torrei, Memecylon wightii, Memecylon royenii, Memecylon semseii, Memecylon zenkeri, Memecylon hookeri, Memecylon varians, Memecylon bremeri, Memecylon gracile, Memecylon sessile, Memecylon afzelii, Memecylon buxoides, Memecylon candidum, Memecylon confusum, Memecylon fragrans, Memecylon occultum, Memecylon perditum, Memecylon rivulare, Memecylon teitense, Memecylon kosiense, Memecylon cuneatum, Memecylon procerum, Memecylon discolor, Memecylon excelsum, Memecylon molestum, Memecylon nervosum, Memecylon elaeagni, Memecylon lawsonii, Memecylon cantleyi, Memecylon kupeanum, Memecylon plebejum, Memecylon simulans, Memecylon boinense, Memecylon caeruleum, Memecylon capuronii, Memecylon deminutum, Memecylon germainii, Memecylon greenwayi, Memecylon lilacinum, Memecylon rostratum, Memecylon sejunctum, Memecylon strumosum, Memecylon ulopterum, Memecylon virescens, Memecylon maxwellii, Memecylon giganteum, Memecylon natalense, Memecylon wallichii, Memecylon heyneanum, Memecylon albescens, Memecylon terminale, Memecylon laurentii, Memecylon cogniauxii, Memecylon dasyanthum, Memecylon eduliforme, Memecylon infuscatum, Memecylon klaineanum, Memecylon longicuspe, Memecylon mayottense, Memecylon clarkeanum, Memecylon nigrescens, Memecylon chevalieri, Memecylon flavescens, Memecylon fruticosum, Memecylon bakerianum, Memecylon orbiculare, Memecylon petiolatum, Memecylon sylvaticum, Memecylon leucanthum, Memecylon urceolatum, Memecylon subramanii, Memecylon polyanthum, Memecylon deccanense, Memecylon sisparense, Memecylon megacarpum, Memecylon umbellatum, Memecylon corticosum, Memecylon fuscescens, Memecylon hyleastrum, Memecylon laxiflorum, Memecylon rotundatum, Memecylon amshoffiae, Memecylon bachmannii, Memecylon batekeanum, Memecylon buxifolium, Memecylon calophyllum, Memecylon talbotianum, Memecylon flavovirens, Memecylon floribundum, Memecylon interjectum, Memecylon louvelianum, Memecylon mocquerysii, Memecylon ovatifolium, Memecylon malabaricum, Memecylon pterocladum, Memecylon scutellatum, Memecylon subcordatum, Memecylon calyptratum, Memecylon ponmudianum, Memecylon gracillimum, Memecylon lanceolatum, Memecylon sahyadricum, Memecylon wayanadense, Memecylon cyanocarpum, Memecylon randerianum, Memecylon pauciflorum, Memecylon sivadasanii, Memecylon paniculatum, Memecylon englerianum, Memecylon parvifolium, Memecylon bakossiense, Memecylon garcinioides, Memecylon corymbiforme, Memecylon longipetalum, Memecylon oubanguianum, Memecylon verruculosum, Memecylon xiphophyllum, Memecylon amplexicaule, Memecylon macrophyllum, Memecylon rhinophyllum, Memecylon scolopacinum, unclassified Memecylon, Memecylon lateriflorum, Memecylon thouarsianum, Memecylon jambosioides, Memecylon lushingtonii, Memecylon capitellatum, Memecylon courtallense, Memecylon erythranthum, Memecylon macrodendron, Memecylon minutiflorum, Memecylon rheophyticum, Memecylon clavistaminum, Memecylon impressivenum, Memecylon magnifoliatum, Memecylon peracuminatum, Memecylon symplociforme, Memecylon torricellense, Memecylon angustifolium, Memecylon viswanathanii, Memecylon travancorense, Memecylon australissimum, Memecylon ligustrifolium, Memecylon kollimalayanum, Memecylon tirunelvelicum, Memecylon pachaimalayanum, Memecylon soutpansbergense, Memecylon schraderbergense, Memecylon mundanthuraianum, Memecylon agastyamalaianum, Memecylon arcuatomarginatum, Memecylon aff. sitanum RDS-2013, Memecylon aff. bachmannii RDS-2017, Memecylon aff. paniculatum SO-2022, Memecylon aff. natalense 1 RDS-2013, Memecylon aff. natalense 2 RDS-2013, Memecylon aff. luchuenense RDS-2013, Memecylon aff. myrianthum 1 RDS-2013, Memecylon aff. myrianthum 2 RDS-2013, Memecylon aff. myrianthum 3 RDS-2013, Memecylon aff. verruculosum RDS-2013, Memecylon aff. lateriflorum 1 RDS-2013, Memecylon aff. lateriflorum 2 RDS-2013, Memecylon aff. lateriflorum 3 RDS-2013

Ellagic acid

6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione

C14H6O8 (302.0062676)


Ellagic acid appears as cream-colored needles (from pyridine) or yellow powder. Odorless. (NTP, 1992) Ellagic acid is an organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates. It has a role as an antioxidant, a food additive, a plant metabolite, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an EC 1.14.18.1 (tyrosinase) inhibitor, an EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor, an EC 2.4.1.1 (glycogen phosphorylase) inhibitor, an EC 2.5.1.18 (glutathione transferase) inhibitor, an EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor, an EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor, an EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor, a skin lightening agent, a fungal metabolite, an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor and a geroprotector. It is an organic heterotetracyclic compound, a cyclic ketone, a lactone, a member of catechols and a polyphenol. It is functionally related to a gallic acid. Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates. In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. Ellagic acid is an investigational drug studied for treatment of Follicular Lymphoma (phase 2 trial), protection from brain injury of intrauterine growth restricted babies (phase 1 and 2 trial), improvement of cardiovascular function in adolescents who are obese (phase 2 trial), and topical treatment of solar lentigines. Ellagic acids therapeutic action mostly involves antioxidant and anti-proliferative effects. Ellagic acid is a natural product found in Fragaria chiloensis, Metrosideros perforata, and other organisms with data available. Ellagic acid is a metabolite found in or produced by Saccharomyces cerevisiae. A fused four ring compound occurring free or combined in galls. Isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used in research and as a dye. Ellagic acid is an organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates. It has a role as an antioxidant, a food additive, a plant metabolite, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an EC 1.14.18.1 (tyrosinase) inhibitor, an EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor, an EC 2.4.1.1 (glycogen phosphorylase) inhibitor, an EC 2.5.1.18 (glutathione transferase) inhibitor, an EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor, an EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor, an EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor, a skin lightening agent, a fungal metabolite and an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. It is an organic heterotetracyclic compound, a cyclic ketone, a lactone, a member of catechols and a polyphenol. It derives from a gallic acid. Ellagic acid, also known as ellagate, belongs to the class of organic compounds known as hydrolyzable tannins. These are tannins with a structure characterized by either of the following models. In model 1, the structure contains galloyl units (in some cases, shikimic acid units) that are linked to diverse polyol carbohydrate-, catechin-, or triterpenoid units. In model 2, contains at least two galloyl units C-C coupled to each other, and do not contain a glycosidically linked catechin unit. The antiproliferative and antioxidant properties of ellagic acid have spurred preliminary research into the potential health benefits of ellagic acid consumption. Ellagic acids therapeutic action mostly involves antioxidant and anti-proliferative/anti-cancer effects. Ellagic acid is found, on average, in the highest concentration within a few different foods, such as chestnuts, common walnuts, and japanese walnuts and in a lower concentration in whiskies, arctic blackberries, and cloudberries. Ellagic acid has also been detected, but not quantified in several different foods, such as lowbush blueberries, bilberries, guava, strawberry guava, and bog bilberries. An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates. Widely distributed in higher plants especies dicotyledons. Intestinal astringent, dietary role disputed. Nutriceutical with anticancer and antioxidation props. Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM. Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM.

   

Ellagic Acid

Ellagic Acid

C14H6O8 (302.0062676)


Origin: Plant, Ellagic acids, Benzopyranoids, Pyrans Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM. Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM.

   

6,7,13-trihydroxy-14-methoxy-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione

6,7,13-trihydroxy-14-methoxy-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione

C15H8O8 (316.0219168)