NCBI Taxonomy: 1079458

Trididemnum cyanophorum (ncbi_taxid: 1079458)

found 27 associated metabolites at species taxonomy rank level.

Ancestor: Trididemnum

Child Taxonomies: none taxonomy data.

Didemnin B

Didemnin B

C57H89N7O15 (1111.6416324000002)


C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C259 - Antineoplastic Antibiotic A natural product found particularly in Lyngbya majuscula and Trididemnum solidum. D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D000890 - Anti-Infective Agents > D000998 - Antiviral Agents C308 - Immunotherapeutic Agent > C574 - Immunosuppressant C784 - Protein Synthesis Inhibitor D000970 - Antineoplastic Agents Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer[1].

   

(2s,3z,3ar)-2-hydroxy-6a-(hydroxymethyl)-3-(prop-2-en-1-ylidene)-2h,3ah-cyclopenta[b]furan-4-one

(2s,3z,3ar)-2-hydroxy-6a-(hydroxymethyl)-3-(prop-2-en-1-ylidene)-2h,3ah-cyclopenta[b]furan-4-one

C11H12O4 (208.0735552)


   

2-{1-[1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-{1,8,11,18-tetrahydroxy-3-[(4-hydroxyphenyl)methyl]-15-isopropyl-6,17-dimethyl-20-(2-methylpropyl)-4,13,16,21-tetraoxo-10-(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}pentanimidic acid

2-{1-[1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-{1,8,11,18-tetrahydroxy-3-[(4-hydroxyphenyl)methyl]-15-isopropyl-6,17-dimethyl-20-(2-methylpropyl)-4,13,16,21-tetraoxo-10-(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}pentanimidic acid

C55H85N7O15 (1083.610334)


   

(2s)-n-[(6s,7s,10s,11s,15s,17r,20r,25as)-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-10-(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

(2s)-n-[(6s,7s,10s,11s,15s,17r,20r,25as)-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-10-(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

C57H89N7O15 (1111.6416324000002)


   

(2r)-n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-15-[(2r)-butan-2-yl]-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

(2r)-n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-15-[(2r)-butan-2-yl]-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

C58H91N7O15 (1125.6572816)


   

4-{[hydroxy(5-hydroxy-3,4-dihydro-2h-pyrrol-2-yl)methylidene]amino}-5-{[1-(2-{methyl[3-methyl-1-({8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-10-(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}-c-hydroxycarbonimidoyl)butyl]carbamoyl}pyrrolidin-1-yl)-1-oxopropan-2-yl]oxy}-5-oxopentanimidic acid

4-{[hydroxy(5-hydroxy-3,4-dihydro-2h-pyrrol-2-yl)methylidene]amino}-5-{[1-(2-{methyl[3-methyl-1-({8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-10-(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}-c-hydroxycarbonimidoyl)butyl]carbamoyl}pyrrolidin-1-yl)-1-oxopropan-2-yl]oxy}-5-oxopentanimidic acid

C67H102N10O19 (1350.7322342)


   

2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-[(3s,6r,7s,10r,11s,15s,17r,20s)-8,11,18-trihydroxy-10,15-diisopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]pentanimidic acid

2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-[(3s,6r,7s,10r,11s,15s,17r,20s)-8,11,18-trihydroxy-10,15-diisopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]pentanimidic acid

C56H87N7O15 (1097.6259832)


   

(2r)-n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-1,8,11,18-tetrahydroxy-3-[(4-hydroxyphenyl)methyl]-15-isopropyl-6,17-dimethyl-20-(2-methylpropyl)-4,13,16,21-tetraoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

(2r)-n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-1,8,11,18-tetrahydroxy-3-[(4-hydroxyphenyl)methyl]-15-isopropyl-6,17-dimethyl-20-(2-methylpropyl)-4,13,16,21-tetraoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

C55H85N7O15 (1083.610334)


   

(2r,3z,3ar,6ar)-2-hydroxy-6a-(hydroxymethyl)-3-(prop-2-en-1-ylidene)-2h,3ah-cyclopenta[b]furan-4-one

(2r,3z,3ar,6ar)-2-hydroxy-6a-(hydroxymethyl)-3-(prop-2-en-1-ylidene)-2h,3ah-cyclopenta[b]furan-4-one

C11H12O4 (208.0735552)


   

2-{1-[1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-{8,11,18-trihydroxy-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-10,15-bis(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}pentanimidic acid

2-{1-[1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-{8,11,18-trihydroxy-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-10,15-bis(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}pentanimidic acid

C58H91N7O15 (1125.6572816)


   

(4s)-5-{[(2s)-1-[(2s)-2-{[(1r)-1-{[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-c-hydroxycarbonimidoyl}-3-methylbutyl](methyl)carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]oxy}-4-({hydroxy[(2s)-5-hydroxy-3,4-dihydro-2h-pyrrol-2-yl]methylidene}amino)-5-oxopentanimidic acid

(4s)-5-{[(2s)-1-[(2s)-2-{[(1r)-1-{[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-c-hydroxycarbonimidoyl}-3-methylbutyl](methyl)carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]oxy}-4-({hydroxy[(2s)-5-hydroxy-3,4-dihydro-2h-pyrrol-2-yl]methylidene}amino)-5-oxopentanimidic acid

C67H102N10O19 (1350.7322342)


   

(2r)-n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

(2r)-n-[(3s,6r,7s,10r,11s,15s,17r,20s,25as)-10-[(2s)-butan-2-yl]-8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-2-{1-[(2s)-1-[(2s)-2-hydroxypropanoyl]pyrrolidin-2-yl]-n-methylformamido}-4-methylpentanimidic acid

C57H89N7O15 (1111.6416324000002)


   

2-{1-[1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-{8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-10-(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}pentanimidic acid

2-{1-[1-(2-hydroxypropanoyl)pyrrolidin-2-yl]-n-methylformamido}-4-methyl-n-{8,11,18-trihydroxy-15-isopropyl-3-[(4-methoxyphenyl)methyl]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,13,16,21-pentaoxo-10-(sec-butyl)-3h,6h,7h,10h,11h,12h,15h,17h,20h,23h,24h,25h,25ah-pyrrolo[2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl}pentanimidic acid

C57H89N7O15 (1111.6416324000002)