Gene Association: GLYATL2

UniProt Search: GLYATL2 (PROTEIN_CODING)
Function Description: glycine-N-acyltransferase like 2

found 10 associated metabolites with current gene based on the text mining result from the pubmed database.

Benzoyl-CoA

{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-[(2-{[2-(benzoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid

C28H40N7O17P3S (871.1414)


Benzoyl-CoA is an intermediate in phenylalanine (as well as benzoate and salicylate) metabolism. In bacteria and gut microflora, benzoyl-CoA is a compound that is formed as a central intermediate in the degradation of a large number of aromatic growth substrates. Benzoyl CoA can be synthesized from hippuric acid and vice versa. [HMDB]. Benzoyl-CoA is found in many foods, some of which are malabar plum, barley, vanilla, and banana. Benzoyl-CoA is an intermediate in phenylalanine (as well as benzoate and salicylate) metabolism. In bacteria and gut microflora, benzoyl-CoA is a compound that is formed as a central intermediate in the degradation of a large number of aromatic growth substrates. Benzoyl CoA can be synthesized from hippuric acid and vice versa. Benzoyl-CoA is a microbial metabolite that can be found in Streptomyces (PMID: 12511484).

   

Oleoyl-CoA

{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-{[2-({2-[(9Z)-octadec-9-enoylsulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid

C39H68N7O17P3S (1031.3605)


Oleoyl-CoA is a substrate for Acyl-CoA desaturase and Protein FAM34A. [HMDB]. Oleoyl-CoA is found in many foods, some of which are cardoon, fruits, hyssop, and rice. Oleoyl-CoA is a substrate for Acyl-CoA desaturase and Protein FAM34A.

   

Phenylacetyl-CoA

{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl-3-{[2-({2-[(2-phenylacetyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid

C29H42N7O17P3S (885.1571)


Phenylacetyl-CoA was found to be a very potent inhibitor of choline acetyltransferase, competitive for acetyl-CoA with Ki of 3.1 X 10(-7)M. Phenylacetate exerts its neurotoxic action through its metabolic product, phenylacetyl-CoA, which could severely decrease the availability of acetyl-CoA. (PMID: 6142928) [HMDB] Phenylacetyl-CoA was found to be a very potent inhibitor of choline acetyltransferase, competitive for acetyl-CoA with Ki of 3.1 X 10(-7)M. Phenylacetate exerts its neurotoxic action through its metabolic product, phenylacetyl-CoA, which could severely decrease the availability of acetyl-CoA (PMID: 6142928).

   

Arachidonyl-CoA

{[(2R,3R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-3-{[2-({2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoylsulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}-2,2-dimethylpropoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid

C41H66N7O17P3S (1053.3449)


Arachidonyl-CoA is an intermediate in Biosynthesis of unsaturated fatty acids. Arachidonyl-CoA is produced from 8,11,14-Eicosatrienoyl-CoA via the enzyme fatty acid desaturase 1 (EC 1.14.19.-). It is then converted to Arachidonic acid via the enzymepalmitoyl-CoA hydrolase (EC 3.1.2.2).

   

oleoyl-CoA

9Z-octadecenoyl-CoA

C39H68N7O17P3S (1031.3605)


An octadecenoyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of oleic acid.

   

CoA 18:1

(9Z)-octadec-9-enoyl-CoA;(9Z)-octadec-9-enoyl-coenzyme A;Oleoyl-coenzyme A;S-Oleoylcoenzyme A;S-[(9Z)-octadec-9-enoyl]-CoA;S-[(9Z)-octadec-9-enoyl]-coenzyme A;S-oleoyl-CoA;cis-9-octadecenoyl-CoA;cis-9-octadecenoyl-coenzyme A;cis-Delta(9)-octadecenoyl-CoA;cis-Delta(9)-octadecenoyl-coenzyme A

C39H68N7O17P3S (1031.3605)


   

CoA 20:4

(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenoyl-CoA;(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenoyl-coenzyme A;(5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoyl-coenzyme A;C20:4-CoA;all-cis-5,8,11,14-eicosatetraenoyl-CoA;all-cis-5,8,11,14-eicosatetraenoyl-coenzyme A;arachidonoyl-coenzyme A;arachidonyl-coenzyme A;cis-Delta(5,8,11,14)-eicosatetraenoyl-CoA;cis-Delta(5,8,11,14)-eicosatetraenoyl-coenzyme A

C41H66N7O17P3S (1053.3449)


   

Arachidonyl-CoA

Arachidonyl-CoA

C41H66N7O17P3S (1053.3449)


   

Phenylacetyl-CoA

Phenylacetyl-CoA

C29H42N7O17P3S (885.1571)


An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of phenylacetic acid.

   

Benzoyl-coa

Benzoyl-coa

C28H40N7O17P3S (871.1414)


The simplest member of the class of benzoyl-CoAs that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of benzoic acid.