Chemical Formula: C16H18N2

Chemical Formula C16H18N2

Found 36 metabolite its formula value is C16H18N2

Agroclavine

InChI=1\C16H18N2\c1-10-6-13-12-4-3-5-14-16(12)11(8-17-14)7-15(13)18(2)9-10\h3-6,8,13,15,17H,7,9H2,1-2H

C16H18N2 (238.147)


An ergot alkaloid that is ergoline which contains a double bond between positions 8 and 9, and which is substituted by methyl groups at positions 6 and 8.

   

Metapramine

N,2-dimethyl-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-9-amine

C16H18N2 (238.147)


   

Nomifensine

2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine

C16H18N2 (238.147)


D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators Nomifensine is a norepinephrine-dopamine reuptake inhibitor that blocks dopamine and norepinephrine reuptake transporters to increase the amount of norepinephrine and dopamine provided to receptors by synapses.

   

4-(4-Aminophenyl)-5,6,7,8-tetrahydronaphthalen-1-amine

4-(4-aminophenyl)-5,6,7,8-tetrahydronaphthalen-1-amine

C16H18N2 (238.147)


   

N,N-Dimethyl-4-(3-pyridin-4-ylprop-1-enyl)aniline

N,N-dimethyl-4-[3-(pyridin-4-yl)prop-1-en-1-yl]aniline

C16H18N2 (238.147)


   

Lysergine

Lysergine

C16H18N2 (238.147)


   

SCHEMBL15828350

4,6-dimethyl-6,11-diazapentacyclo[7.6.1.02,4.02,7.012,16]hexadeca-1(16),9,12,14-tetraene

C16H18N2 (238.147)


   

Nomifensine

2-methyl-4-phenyl-3,4-dihydro-1H-isoquinolin-8-amine

C16H18N2 (238.147)


D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents D049990 - Membrane Transport Modulators ORIGINAL_PRECURSOR_SCAN_NO 6773; CONFIDENCE standard compound; INTERNAL_ID 455; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6775 CONFIDENCE standard compound; INTERNAL_ID 455; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6775; ORIGINAL_PRECURSOR_SCAN_NO 6773 CONFIDENCE standard compound; INTERNAL_ID 455; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6815; ORIGINAL_PRECURSOR_SCAN_NO 6814 CONFIDENCE standard compound; INTERNAL_ID 455; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6815; ORIGINAL_PRECURSOR_SCAN_NO 6812 CONFIDENCE standard compound; INTERNAL_ID 455; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6843; ORIGINAL_PRECURSOR_SCAN_NO 6841 CONFIDENCE standard compound; INTERNAL_ID 455; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6841; ORIGINAL_PRECURSOR_SCAN_NO 6839 CONFIDENCE standard compound; INTERNAL_ID 455; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 6852; ORIGINAL_PRECURSOR_SCAN_NO 6850 Nomifensine is a norepinephrine-dopamine reuptake inhibitor that blocks dopamine and norepinephrine reuptake transporters to increase the amount of norepinephrine and dopamine provided to receptors by synapses.

   

Metapramine

N,11-dimethyl-5,6-dihydrobenzo[b][1]benzazepin-5-amine

C16H18N2 (238.147)


C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent > C94727 - Tricyclic Antidepressant D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents

   

Nomifensin

Nomifensin

C16H18N2 (238.147)


   

1-(4-biphenylyl)-piperazine

1-(4-biphenylyl)-piperazine

C16H18N2 (238.147)


   

(2-Benzylisoindolin-4-yl)methanamine

(2-Benzylisoindolin-4-yl)methanamine

C16H18N2 (238.147)


   

Piperazine,1,4-diphenyl-

Piperazine,1,4-diphenyl-

C16H18N2 (238.147)


   

2-(4-PHENYLPHENYL)PIPERAZINE

2-(4-PHENYLPHENYL)PIPERAZINE

C16H18N2 (238.147)


   

Pyridine, 4-[1-(phenylmethyl)-3-pyrrolidinyl]-

Pyridine, 4-[1-(phenylmethyl)-3-pyrrolidinyl]-

C16H18N2 (238.147)


   

N-(pyridin-4-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-amine

N-(pyridin-4-ylmethyl)-1,2,3,4-tetrahydronaphthalen-1-amine

C16H18N2 (238.147)


   

2,3-diphenylpiperazine

2,3-diphenylpiperazine

C16H18N2 (238.147)


   

N-(2,5-DIMETHYLBENZYL)ETHANE-1,2-DIAMINE

N-(2,5-DIMETHYLBENZYL)ETHANE-1,2-DIAMINE

C16H18N2 (238.147)


   

2-(1-benzylpyrrolidin-3-yl)pyridine

2-(1-benzylpyrrolidin-3-yl)pyridine

C16H18N2 (238.147)


   

4-Amino-4-(N,N-dimethylamino)stilbene

4-Amino-4-(N,N-dimethylamino)stilbene

C16H18N2 (238.147)


   

2,2-Diphenylpiperazine

2,2-Diphenylpiperazine

C16H18N2 (238.147)


   

1-(Diphenylmethyl)-3-azetidinamine

1-(Diphenylmethyl)-3-azetidinamine

C16H18N2 (238.147)


   

1-(2-Biphenyl)Piperazine 2Hcl

1-(2-Biphenyl)Piperazine 2Hcl

C16H18N2 (238.147)


   

1H-Indole,2,3-dihydro-7-(1-methylethyl)-2-(3-pyridinyl)-(9CI)

1H-Indole,2,3-dihydro-7-(1-methylethyl)-2-(3-pyridinyl)-(9CI)

C16H18N2 (238.147)


   

(2-METHOXYPHENYL)METHYLCYANOCARBONIMIDODITHIOATE

(2-METHOXYPHENYL)METHYLCYANOCARBONIMIDODITHIOATE

C16H18N2 (238.147)


   

1-(3-biphenylyl)piperazine

1-(3-biphenylyl)piperazine

C16H18N2 (238.147)


   

1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine

1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine

C16H18N2 (238.147)


PhiKan 083 is a carbazole derivative, which binds to the surface cavity and stabilizes Y220C (a p53 mutant), with a Kd of 167 μM. PhiKan 083 can be used for cancer research[1].

   

(+)-Nomifensine

(+)-Nomifensine

C16H18N2 (238.147)


   

N,N-Dimethyl-4-(3-pyridin-4-ylprop-1-enyl)aniline

N,N-Dimethyl-4-(3-pyridin-4-ylprop-1-enyl)aniline

C16H18N2 (238.147)


   

(-)-Nomifensine

(-)-Nomifensine

C16H18N2 (238.147)


   

N-butyl-N-methyl-2-benzo[cd]indolamine

N-butyl-N-methyl-2-benzo[cd]indolamine

C16H18N2 (238.147)


   

(2s,7r)-4,6-dimethyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),3,9,12,14-pentaene

(2s,7r)-4,6-dimethyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),3,9,12,14-pentaene

C16H18N2 (238.147)


   

cycloclavine

cycloclavine

C16H18N2 (238.147)


   

(2s,7s)-4,6-dimethyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),3,9,12,14-pentaene

(2s,7s)-4,6-dimethyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),3,9,12,14-pentaene

C16H18N2 (238.147)


   

4,6-dimethyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),3,9,12,14-pentaene

4,6-dimethyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),3,9,12,14-pentaene

C16H18N2 (238.147)


   

4,6-dimethyl-6,11-diazapentacyclo[7.6.1.0²,⁴.0²,⁷.0¹²,¹⁶]hexadeca-1(16),9,12,14-tetraene

4,6-dimethyl-6,11-diazapentacyclo[7.6.1.0²,⁴.0²,⁷.0¹²,¹⁶]hexadeca-1(16),9,12,14-tetraene

C16H18N2 (238.147)