Exact Mass: 892.3000942000001
Exact Mass Matches: 892.3000942000001
Found 6 metabolites which its exact mass value is equals to given mass value 892.3000942000001,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
4-O-[6-O-(5-O-syringoyl-beta-D-apiofuranosyl)-beta-D-glucopyranosyl]-(+)-(7S,7S,8R,8R)-4-hydroxy-3,3,5,5-tetramethoxy-7,9:7,9-diepoxylignane|obtusifoside B
4-O-[6-O-(5-O-syringoyl-beta-D-apiofuranosyl)-beta-D-glucopyranosyl]-(+)-(7S,7S,8R,8R)-4-hydroxy-3,3,5,5-tetramethoxy-7,9:7,9-diepoxylignane|obtusifoside B
MD-222
MD-222
C48H47Cl2FN6O6 (892.2917994000002)
MD-222 is the first-in-class highly potent PROTAC degrader of MDM2. MD-222 consists of ligands for Cereblon and MDM2. MD-222 induces rapid degradation of the MDM2 protein and activation of wild-type p53 in cells. MD-222 has anticancer effects[1][2].
4-{[4-(acetyloxy)-3,5-dihydroxyoxan-2-yl]oxy}-5-hydroxy-6-{[5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-3-yl]oxy}-2-methyloxan-3-yl acetate
4-{[4-(acetyloxy)-3,5-dihydroxyoxan-2-yl]oxy}-5-hydroxy-6-{[5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-3-yl]oxy}-2-methyloxan-3-yl acetate
(2s,3s,4r,5s,6s)-4-{[(2s,3s,4r,5r)-4-(acetyloxy)-3,5-dihydroxyoxan-2-yl]oxy}-5-hydroxy-6-{[5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-{[(2s,3r,4s,5s,6s)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-3-yl]oxy}-2-methyloxan-3-yl acetate
(2s,3s,4r,5s,6s)-4-{[(2s,3s,4r,5r)-4-(acetyloxy)-3,5-dihydroxyoxan-2-yl]oxy}-5-hydroxy-6-{[5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-{[(2s,3r,4s,5s,6s)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-3-yl]oxy}-2-methyloxan-3-yl acetate
(2s,3s,4s,5r,6s)-4-{[(2s,3r,4s,5r)-4-(acetyloxy)-3,5-dihydroxyoxan-2-yl]oxy}-5-hydroxy-6-{[5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-3-yl]oxy}-2-methyloxan-3-yl acetate
(2s,3s,4s,5r,6s)-4-{[(2s,3r,4s,5r)-4-(acetyloxy)-3,5-dihydroxyoxan-2-yl]oxy}-5-hydroxy-6-{[5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-7-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}chromen-3-yl]oxy}-2-methyloxan-3-yl acetate