Exact Mass: 863.4428836000001

Exact Mass Matches: 863.4428836000001

Found 4 metabolites which its exact mass value is equals to given mass value 863.4428836000001, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Casomorphin

4-{[2-({2-[({1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl}(hydroxy)methylidene)amino]-1-hydroxy-3-phenylpropylidene}amino)-1-hydroxy-3-methylbutylidene]amino}-5-{2-[(1-carboxy-2-methylbutyl)-C-hydroxycarbonimidoyl]pyrrolidin-1-yl}-5-oxopentanoic acid

C44H61N7O11 (863.4428836000001)


Casomorphin is a 7-residue opiod peptide (Tyr-Pro-Phe-Pro-Gly-Pro-Ile) peptide derived from the milk protein casein. Casein is one of the major proteins in the milk of all mammals including cows, goats, and humans. It has been reported that urine samples from people with autism, celiac disease and schizophrenia contain high amounts of the casomorphin peptide. These peptides could also be elevated in other disorders such as chronic fatigue, fibromyalgia, and depression based on anecdotal reports of symptom remission after exclusion of wheat and dairy. The scientific evidence for this diet and its effects is still disputed.

   

β-Casomorphin (human)

H-Tyr-Pro-Phe-Val-Glu-Pro-Ile-OH

C44H61N7O11 (863.4428836000001)


   

Tyr-Pro-Phe-Val-Glu-Pro-Ile

Tyr-Pro-Phe-Val-Glu-Pro-Ile

C44H61N7O11 (863.4428836000001)


   

beta-casomorphin-7 (human)

beta-casomorphin-7 (human)

C44H61N7O11 (863.4428836000001)


A seven amino acid oligopeptide fragment of the human milk protein, beta-casein. It is an inhibitor of pancreatic elastase, 5-HT2-serotonin receptors, mu-opioid receptors and delta-opioid receptors.