Exact Mass: 777.4792

Exact Mass Matches: 777.4792

Found 34 metabolites which its exact mass value is equals to given mass value 777.4792, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

PE(14:0/6 keto-PGF1alpha)

(2-aminoethoxy)[(2R)-2-({7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]-6-oxoheptanoyl}oxy)-3-(tetradecanoyloxy)propoxy]phosphinic acid

C39H72NO12P (777.4792)


PE(14:0/6 keto-PGF1alpha) is an oxidized phosphatidylethanolamine (PE). Oxidized phosphatidylethanolamines are glycerophospholipids in which a phosphorylethanolamine moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidylethanolamines belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidylethanolamines can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PE(14:0/6 keto-PGF1alpha), in particular, consists of one chain of one tetradecanoyl at the C-1 position and one chain of 6-Keto-prostaglandin F1alpha at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PEs can be synthesized via three different routes. In one route, the oxidized PE is synthetized de novo following the same mechanisms as for PEs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PE backbone, mainly through the action of LOX (PMID: 33329396).

   

PE(6 keto-PGF1alpha/14:0)

(2-aminoethoxy)[(2R)-3-({7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]-6-oxoheptanoyl}oxy)-2-(tetradecanoyloxy)propoxy]phosphinic acid

C39H72NO12P (777.4792)


PE(6 keto-PGF1alpha/14:0) is an oxidized phosphatidylethanolamine (PE). Oxidized phosphatidylethanolamines are glycerophospholipids in which a phosphorylethanolamine moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidylethanolamines belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidylethanolamines can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PE(6 keto-PGF1alpha/14:0), in particular, consists of one chain of one 6-Keto-prostaglandin F1alpha at the C-1 position and one chain of tetradecanoyl at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PEs can be synthesized via three different routes. In one route, the oxidized PE is synthetized de novo following the same mechanisms as for PEs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PE backbone, mainly through the action of LOX (PMID: 33329396).

   

PE(14:0/TXB2)

(2-aminoethoxy)[(2R)-2-{[(5Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]oxan-3-yl]hept-5-enoyl]oxy}-3-(tetradecanoyloxy)propoxy]phosphinic acid

C39H72NO12P (777.4792)


PE(14:0/TXB2) is an oxidized phosphatidylethanolamine (PE). Oxidized phosphatidylethanolamines are glycerophospholipids in which a phosphorylethanolamine moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidylethanolamines belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidylethanolamines can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PE(14:0/TXB2), in particular, consists of one chain of one tetradecanoyl at the C-1 position and one chain of Thromboxane B2 at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PEs can be synthesized via three different routes. In one route, the oxidized PE is synthetized de novo following the same mechanisms as for PEs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PE backbone, mainly through the action of LOX (PMID: 33329396).

   

PE(TXB2/14:0)

(2-aminoethoxy)[(2R)-3-{[(5Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]oxan-3-yl]hept-5-enoyl]oxy}-2-(tetradecanoyloxy)propoxy]phosphinic acid

C39H72NO12P (777.4792)


PE(TXB2/14:0) is an oxidized phosphatidylethanolamine (PE). Oxidized phosphatidylethanolamines are glycerophospholipids in which a phosphorylethanolamine moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidylethanolamines belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidylethanolamines can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PE(TXB2/14:0), in particular, consists of one chain of one Thromboxane B2 at the C-1 position and one chain of tetradecanoyl at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PEs can be synthesized via three different routes. In one route, the oxidized PE is synthetized de novo following the same mechanisms as for PEs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PE backbone, mainly through the action of LOX (PMID: 33329396).

   

PE(14:0/6 keto-PGF1alpha)

PE(14:0/6 keto-PGF1alpha)

C39H72NO12P (777.4792)


   

PE(6 keto-PGF1alpha/14:0)

PE(6 keto-PGF1alpha/14:0)

C39H72NO12P (777.4792)


   
   
   
   

PI-Cer 21:3;2O/12:0;O

PI-Cer 21:3;2O/12:0;O

C39H72NO12P (777.4792)


   

PI-Cer 18:2;2O/15:1;O

PI-Cer 18:2;2O/15:1;O

C39H72NO12P (777.4792)


   

PI-Cer 14:2;2O/19:1;O

PI-Cer 14:2;2O/19:1;O

C39H72NO12P (777.4792)


   

PI-Cer 18:3;2O/15:0;O

PI-Cer 18:3;2O/15:0;O

C39H72NO12P (777.4792)


   

PI-Cer 13:2;2O/20:1;O

PI-Cer 13:2;2O/20:1;O

C39H72NO12P (777.4792)


   

PI-Cer 19:2;2O/14:1;O

PI-Cer 19:2;2O/14:1;O

C39H72NO12P (777.4792)


   

PI-Cer 12:2;2O/21:1;O

PI-Cer 12:2;2O/21:1;O

C39H72NO12P (777.4792)


   

PI-Cer 21:2;2O/12:1;O

PI-Cer 21:2;2O/12:1;O

C39H72NO12P (777.4792)


   

PI-Cer 20:2;2O/13:1;O

PI-Cer 20:2;2O/13:1;O

C39H72NO12P (777.4792)


   

PI-Cer 20:3;2O/13:0;O

PI-Cer 20:3;2O/13:0;O

C39H72NO12P (777.4792)


   

PI-Cer 15:2;2O/18:1;O

PI-Cer 15:2;2O/18:1;O

C39H72NO12P (777.4792)


   

PI-Cer 17:2;2O/16:1;O

PI-Cer 17:2;2O/16:1;O

C39H72NO12P (777.4792)


   

PI-Cer 16:3;2O/17:0;O

PI-Cer 16:3;2O/17:0;O

C39H72NO12P (777.4792)


   

PI-Cer 15:3;2O/18:0;O

PI-Cer 15:3;2O/18:0;O

C39H72NO12P (777.4792)


   

PI-Cer 13:1;2O/20:2;O

PI-Cer 13:1;2O/20:2;O

C39H72NO12P (777.4792)


   

PI-Cer 14:3;2O/19:0;O

PI-Cer 14:3;2O/19:0;O

C39H72NO12P (777.4792)


   

PI-Cer 15:1;2O/18:2;O

PI-Cer 15:1;2O/18:2;O

C39H72NO12P (777.4792)


   

PI-Cer 19:3;2O/14:0;O

PI-Cer 19:3;2O/14:0;O

C39H72NO12P (777.4792)


   

PI-Cer 17:1;2O/16:2;O

PI-Cer 17:1;2O/16:2;O

C39H72NO12P (777.4792)


   

PI-Cer 17:3;2O/16:0;O

PI-Cer 17:3;2O/16:0;O

C39H72NO12P (777.4792)


   
   
   

IPC 15:2;O2/18:1;O

IPC 15:2;O2/18:1;O

C39H72NO12P (777.4792)


   
   

22-benzyl-5,14,24,27-tetrahydroxy-12-isopropyl-3-(2-methylpropyl)-25-(sec-butyl)-1,4,10,13,19,23,26-heptaazatetracyclo[26.3.0.0⁶,¹⁰.0¹⁵,¹⁹]hentriaconta-4,13,23,26-tetraene-2,11,21-trione

22-benzyl-5,14,24,27-tetrahydroxy-12-isopropyl-3-(2-methylpropyl)-25-(sec-butyl)-1,4,10,13,19,23,26-heptaazatetracyclo[26.3.0.0⁶,¹⁰.0¹⁵,¹⁹]hentriaconta-4,13,23,26-tetraene-2,11,21-trione

C42H63N7O7 (777.4789)