Exact Mass: 777.4789

Exact Mass Matches: 777.4789

Found 70 metabolites which its exact mass value is equals to given mass value 777.4789, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

2-Furoyl-LIGRLO-amide

N-({[1-({1-[(4-amino-1-carbamoylbutyl)carbamoyl]-3-methylbutyl}carbamoyl)-4-[(diaminomethylidene)amino]butyl]carbamoyl}methyl)-2-{2-[(furan-2-yl)formamido]-4-methylpentanamido}-3-methylpentanamide

C36H63N11O8 (777.4861)


   

PE(14:0/6 keto-PGF1alpha)

(2-aminoethoxy)[(2R)-2-({7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]-6-oxoheptanoyl}oxy)-3-(tetradecanoyloxy)propoxy]phosphinic acid

C39H72NO12P (777.4792)


PE(14:0/6 keto-PGF1alpha) is an oxidized phosphatidylethanolamine (PE). Oxidized phosphatidylethanolamines are glycerophospholipids in which a phosphorylethanolamine moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidylethanolamines belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidylethanolamines can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PE(14:0/6 keto-PGF1alpha), in particular, consists of one chain of one tetradecanoyl at the C-1 position and one chain of 6-Keto-prostaglandin F1alpha at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PEs can be synthesized via three different routes. In one route, the oxidized PE is synthetized de novo following the same mechanisms as for PEs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PE backbone, mainly through the action of LOX (PMID: 33329396).

   

PE(6 keto-PGF1alpha/14:0)

(2-aminoethoxy)[(2R)-3-({7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]cyclopentyl]-6-oxoheptanoyl}oxy)-2-(tetradecanoyloxy)propoxy]phosphinic acid

C39H72NO12P (777.4792)


PE(6 keto-PGF1alpha/14:0) is an oxidized phosphatidylethanolamine (PE). Oxidized phosphatidylethanolamines are glycerophospholipids in which a phosphorylethanolamine moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidylethanolamines belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidylethanolamines can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PE(6 keto-PGF1alpha/14:0), in particular, consists of one chain of one 6-Keto-prostaglandin F1alpha at the C-1 position and one chain of tetradecanoyl at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PEs can be synthesized via three different routes. In one route, the oxidized PE is synthetized de novo following the same mechanisms as for PEs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PE backbone, mainly through the action of LOX (PMID: 33329396).

   

PE(14:0/TXB2)

(2-aminoethoxy)[(2R)-2-{[(5Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]oxan-3-yl]hept-5-enoyl]oxy}-3-(tetradecanoyloxy)propoxy]phosphinic acid

C39H72NO12P (777.4792)


PE(14:0/TXB2) is an oxidized phosphatidylethanolamine (PE). Oxidized phosphatidylethanolamines are glycerophospholipids in which a phosphorylethanolamine moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidylethanolamines belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidylethanolamines can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PE(14:0/TXB2), in particular, consists of one chain of one tetradecanoyl at the C-1 position and one chain of Thromboxane B2 at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PEs can be synthesized via three different routes. In one route, the oxidized PE is synthetized de novo following the same mechanisms as for PEs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PE backbone, mainly through the action of LOX (PMID: 33329396).

   

PE(TXB2/14:0)

(2-aminoethoxy)[(2R)-3-{[(5Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]oxan-3-yl]hept-5-enoyl]oxy}-2-(tetradecanoyloxy)propoxy]phosphinic acid

C39H72NO12P (777.4792)


PE(TXB2/14:0) is an oxidized phosphatidylethanolamine (PE). Oxidized phosphatidylethanolamines are glycerophospholipids in which a phosphorylethanolamine moiety occupies a glycerol substitution site and at least one of the fatty acyl chains has undergone oxidation. As all oxidized lipids, oxidized phosphatidylethanolamines belong to a group of biomolecules that have a role as signaling molecules. The biosynthesis of oxidized lipids is mediated by several enzymatic families, including cyclooxygenases (COX), lipoxygenases (LOX) and cytochrome P450s (CYP). Non-enzymatically oxidized lipids are produced by uncontrolled oxidation through free radicals and are considered harmful to human health (PMID: 33329396). As is the case with diacylglycerols, phosphatidylethanolamines can have many different combinations of fatty acids of varying lengths, saturation and degrees of oxidation attached at the C-1 and C-2 positions. PE(TXB2/14:0), in particular, consists of one chain of one Thromboxane B2 at the C-1 position and one chain of tetradecanoyl at the C-2 position. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling. Similarly to what occurs with phospholipids, the fatty acid distribution at the C-1 and C-2 positions of glycerol within oxidized phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. Oxidized PEs can be synthesized via three different routes. In one route, the oxidized PE is synthetized de novo following the same mechanisms as for PEs but incorporating oxidized acyl chains (PMID: 33329396). An alternative is the transacylation of one of the non-oxidized acyl chains with an oxidized acylCoA (PMID: 33329396). The third pathway results from the oxidation of the acyl chain while still attached to the PE backbone, mainly through the action of LOX (PMID: 33329396).

   

PE(14:0/6 keto-PGF1alpha)

PE(14:0/6 keto-PGF1alpha)

C39H72NO12P (777.4792)


   

PE(6 keto-PGF1alpha/14:0)

PE(6 keto-PGF1alpha/14:0)

C39H72NO12P (777.4792)


   
   
   
   
   

SHexCer 20:2;2O/13:1;O

SHexCer 20:2;2O/13:1;O

C39H71NO12S (777.4697)


   

SHexCer 18:2;2O/15:1;O

SHexCer 18:2;2O/15:1;O

C39H71NO12S (777.4697)


   

SHexCer 15:2;2O/18:1;O

SHexCer 15:2;2O/18:1;O

C39H71NO12S (777.4697)


   

SHexCer 14:3;2O/19:0;O

SHexCer 14:3;2O/19:0;O

C39H71NO12S (777.4697)


   

SHexCer 19:2;2O/14:1;O

SHexCer 19:2;2O/14:1;O

C39H71NO12S (777.4697)


   

SHexCer 20:3;2O/13:0;O

SHexCer 20:3;2O/13:0;O

C39H71NO12S (777.4697)


   

SHexCer 21:3;2O/12:0;O

SHexCer 21:3;2O/12:0;O

C39H71NO12S (777.4697)


   

SHexCer 16:3;2O/17:0;O

SHexCer 16:3;2O/17:0;O

C39H71NO12S (777.4697)


   

SHexCer 12:2;2O/21:1;O

SHexCer 12:2;2O/21:1;O

C39H71NO12S (777.4697)


   

SHexCer 17:3;2O/16:0;O

SHexCer 17:3;2O/16:0;O

C39H71NO12S (777.4697)


   

SHexCer 17:1;2O/16:2;O

SHexCer 17:1;2O/16:2;O

C39H71NO12S (777.4697)


   

SHexCer 21:2;2O/12:1;O

SHexCer 21:2;2O/12:1;O

C39H71NO12S (777.4697)


   

SHexCer 11:1;2O/22:2;O

SHexCer 11:1;2O/22:2;O

C39H71NO12S (777.4697)


   

SHexCer 15:1;2O/18:2;O

SHexCer 15:1;2O/18:2;O

C39H71NO12S (777.4697)


   

SHexCer 13:2;2O/20:1;O

SHexCer 13:2;2O/20:1;O

C39H71NO12S (777.4697)


   

SHexCer 15:3;2O/18:0;O

SHexCer 15:3;2O/18:0;O

C39H71NO12S (777.4697)


   

SHexCer 17:2;2O/16:1;O

SHexCer 17:2;2O/16:1;O

C39H71NO12S (777.4697)


   

SHexCer 14:2;2O/19:1;O

SHexCer 14:2;2O/19:1;O

C39H71NO12S (777.4697)


   

SHexCer 13:1;2O/20:2;O

SHexCer 13:1;2O/20:2;O

C39H71NO12S (777.4697)


   

SHexCer 18:3;2O/15:0;O

SHexCer 18:3;2O/15:0;O

C39H71NO12S (777.4697)


   

SHexCer 19:3;2O/14:0;O

SHexCer 19:3;2O/14:0;O

C39H71NO12S (777.4697)


   

PI-Cer 21:3;2O/12:0;O

PI-Cer 21:3;2O/12:0;O

C39H72NO12P (777.4792)


   

PI-Cer 18:2;2O/15:1;O

PI-Cer 18:2;2O/15:1;O

C39H72NO12P (777.4792)


   

PI-Cer 14:2;2O/19:1;O

PI-Cer 14:2;2O/19:1;O

C39H72NO12P (777.4792)


   

PI-Cer 18:3;2O/15:0;O

PI-Cer 18:3;2O/15:0;O

C39H72NO12P (777.4792)


   

PI-Cer 13:2;2O/20:1;O

PI-Cer 13:2;2O/20:1;O

C39H72NO12P (777.4792)


   

PI-Cer 19:2;2O/14:1;O

PI-Cer 19:2;2O/14:1;O

C39H72NO12P (777.4792)


   

PI-Cer 12:2;2O/21:1;O

PI-Cer 12:2;2O/21:1;O

C39H72NO12P (777.4792)


   

PI-Cer 21:2;2O/12:1;O

PI-Cer 21:2;2O/12:1;O

C39H72NO12P (777.4792)


   

PI-Cer 20:2;2O/13:1;O

PI-Cer 20:2;2O/13:1;O

C39H72NO12P (777.4792)


   

PI-Cer 20:3;2O/13:0;O

PI-Cer 20:3;2O/13:0;O

C39H72NO12P (777.4792)


   

PI-Cer 15:2;2O/18:1;O

PI-Cer 15:2;2O/18:1;O

C39H72NO12P (777.4792)


   

PI-Cer 17:2;2O/16:1;O

PI-Cer 17:2;2O/16:1;O

C39H72NO12P (777.4792)


   

PI-Cer 16:3;2O/17:0;O

PI-Cer 16:3;2O/17:0;O

C39H72NO12P (777.4792)


   

PI-Cer 15:3;2O/18:0;O

PI-Cer 15:3;2O/18:0;O

C39H72NO12P (777.4792)


   

PI-Cer 13:1;2O/20:2;O

PI-Cer 13:1;2O/20:2;O

C39H72NO12P (777.4792)


   

PI-Cer 14:3;2O/19:0;O

PI-Cer 14:3;2O/19:0;O

C39H72NO12P (777.4792)


   

PI-Cer 15:1;2O/18:2;O

PI-Cer 15:1;2O/18:2;O

C39H72NO12P (777.4792)


   

PI-Cer 19:3;2O/14:0;O

PI-Cer 19:3;2O/14:0;O

C39H72NO12P (777.4792)


   

PI-Cer 17:1;2O/16:2;O

PI-Cer 17:1;2O/16:2;O

C39H72NO12P (777.4792)


   

PI-Cer 17:3;2O/16:0;O

PI-Cer 17:3;2O/16:0;O

C39H72NO12P (777.4792)


   
   
   

Hex2Cer 14:2;O2/13:0;O

Hex2Cer 14:2;O2/13:0;O

C39H71NO14 (777.4874)


   

Hex2Cer 15:2;O2/12:0;O

Hex2Cer 15:2;O2/12:0;O

C39H71NO14 (777.4874)


   

Hex2Cer 16:2;O2/11:0;O

Hex2Cer 16:2;O2/11:0;O

C39H71NO14 (777.4874)


   

Hex2Cer 17:2;O2/10:0;O

Hex2Cer 17:2;O2/10:0;O

C39H71NO14 (777.4874)


   

Hex2Cer 27:2;O2;O

Hex2Cer 27:2;O2;O

C39H71NO14 (777.4874)


   

LacCer 14:2;O2/13:0;O

LacCer 14:2;O2/13:0;O

C39H71NO14 (777.4874)


   

LacCer 15:2;O2/12:0;O

LacCer 15:2;O2/12:0;O

C39H71NO14 (777.4874)


   

LacCer 16:2;O2/11:0;O

LacCer 16:2;O2/11:0;O

C39H71NO14 (777.4874)


   

LacCer 17:2;O2/10:0;O

LacCer 17:2;O2/10:0;O

C39H71NO14 (777.4874)


   

LacCer 27:2;O2;O

LacCer 27:2;O2;O

C39H71NO14 (777.4874)


   
   

IPC 15:2;O2/18:1;O

IPC 15:2;O2/18:1;O

C39H72NO12P (777.4792)


   
   

2-Furoyl-LIGRLO-amide

2-Furoyl-LIGRLO-amide

C36H63N11O8 (777.4861)


2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0[1][2]..

   

(2r)-2-[(hydroxymethylidene)amino]-3-methyl-n-[(3r,6s,13r,16r,19r,20s,23s)-5,15,18-trihydroxy-13-isopropyl-20-methyl-3,16-bis(2-methylpropyl)-2,12,22-trioxo-21-oxa-1,4,10,11,14,17,27-heptaazatricyclo[21.4.0.0⁶,¹¹]heptacosa-4,14,17-trien-19-yl]butanimidic acid

(2r)-2-[(hydroxymethylidene)amino]-3-methyl-n-[(3r,6s,13r,16r,19r,20s,23s)-5,15,18-trihydroxy-13-isopropyl-20-methyl-3,16-bis(2-methylpropyl)-2,12,22-trioxo-21-oxa-1,4,10,11,14,17,27-heptaazatricyclo[21.4.0.0⁶,¹¹]heptacosa-4,14,17-trien-19-yl]butanimidic acid

C37H63N9O9 (777.4749)


   

22-benzyl-5,14,24,27-tetrahydroxy-12-isopropyl-3-(2-methylpropyl)-25-(sec-butyl)-1,4,10,13,19,23,26-heptaazatetracyclo[26.3.0.0⁶,¹⁰.0¹⁵,¹⁹]hentriaconta-4,13,23,26-tetraene-2,11,21-trione

22-benzyl-5,14,24,27-tetrahydroxy-12-isopropyl-3-(2-methylpropyl)-25-(sec-butyl)-1,4,10,13,19,23,26-heptaazatetracyclo[26.3.0.0⁶,¹⁰.0¹⁵,¹⁹]hentriaconta-4,13,23,26-tetraene-2,11,21-trione

C42H63N7O7 (777.4789)