Exact Mass: 581.1284307999999
Exact Mass Matches: 581.1284307999999
Found 1 metabolites which its exact mass value is equals to given mass value 581.1284307999999,
within given mass tolerance error 8.0E-6 dalton. Try search metabolite list with more accurate mass tolerance error
1.6E-6 dalton.
MI-1061
MI-1061
C30H26Cl2FN3O4 (581.1284307999999)
MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity[1].
