Exact Mass: 581.1284307999999
Exact Mass Matches: 581.1284307999999
Found 1 metabolites which its exact mass value is equals to given mass value 581.1284307999999,
within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error
4.0E-5 dalton.
MI-1061
MI-1061
C30H26Cl2FN3O4 (581.1284307999999)
MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 potently activates p53 and induces apoptosis in the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity[1].
