Exact Mass: 575.2631
Exact Mass Matches: 575.2631
Found 120 metabolites which its exact mass value is equals to given mass value 575.2631
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
His Glu Tyr Lys
Asp Lys Gln Trp
Asp Lys Trp Gln
Asp Gln Lys Trp
Asp Gln Trp Lys
Asp Trp Lys Gln
Asp Trp Gln Lys
Glu Glu Ile Trp
Glu Glu Leu Trp
Glu Glu Trp Ile
Glu Glu Trp Leu
Glu His Lys Tyr
Glu His Tyr Lys
Glu Ile Glu Trp
Glu Ile Trp Glu
Glu Lys His Tyr
Glu Lys Asn Trp
Glu Lys Trp Asn
Glu Lys Tyr His
Glu Leu Glu Trp
Glu Leu Trp Glu
Glu Asn Lys Trp
Glu Asn Trp Lys
Glu Trp Glu Ile
Glu Trp Glu Leu
Glu Trp Ile Glu
Glu Trp Lys Asn
Glu Trp Leu Glu
Glu Trp Asn Lys
Glu Tyr His Lys
Glu Tyr Lys His
His Glu Lys Tyr
His His Pro Trp
His His Trp Pro
His Lys Glu Tyr
His Lys Tyr Glu
His Pro His Trp
His Pro Trp His
His Trp His Pro
His Trp Pro His
His Tyr Glu Lys
His Tyr Lys Glu
Ile Glu Glu Trp
Ile Glu Trp Glu
Ile Trp Glu Glu
Lys Asp Gln Trp
Lys Asp Trp Gln
Lys Glu His Tyr
Lys Glu Asn Trp
Lys Glu Trp Asn
Lys Glu Tyr His
Lys His Glu Tyr
Lys His Tyr Glu
Lys Asn Glu Trp
Lys Asn Trp Glu
Lys Gln Asp Trp
Lys Gln Trp Asp
Lys Trp Asp Gln
Lys Trp Glu Asn
Lys Trp Asn Glu
Lys Trp Gln Asp
Lys Tyr Glu His
Lys Tyr His Glu
Leu Glu Glu Trp
Leu Glu Trp Glu
Leu Trp Glu Glu
Asn Glu Lys Trp
Asn Glu Trp Lys
Asn Lys Glu Trp
Asn Lys Trp Glu
Asn Trp Glu Lys
Asn Trp Lys Glu
Pro His His Trp
Pro His Trp His
Pro Trp His His
Gln Asp Lys Trp
Gln Asp Trp Lys
Gln Lys Asp Trp
Gln Lys Trp Asp
Gln Trp Asp Lys
Gln Trp Lys Asp
Trp Asp Lys Gln
Trp Asp Gln Lys
Trp Glu Glu Ile
Trp Glu Glu Leu
Trp Glu Ile Glu
Trp Glu Lys Asn
Trp Glu Leu Glu
Trp Glu Asn Lys
Trp His His Pro
Trp His Pro His
Trp Ile Glu Glu
Trp Lys Asp Gln
Trp Lys Glu Asn
Trp Lys Asn Glu
Trp Lys Gln Asp
Trp Leu Glu Glu
Trp Asn Glu Lys
Trp Asn Lys Glu
Trp Pro His His
Trp Gln Asp Lys
Trp Gln Lys Asp
Tyr Glu His Lys
Tyr Glu Lys His
Tyr His Glu Lys
Tyr His Lys Glu
Tyr Lys Glu His
Tyr Lys His Glu
Tandospirone Citrate
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent C78272 - Agent Affecting Nervous System > C47794 - Serotonin Agonist Tandospirone citrate is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM). IC50 Value: 27±5 nM(Ki) [1] Target: 5-HT1A in vitro: Tandospirone is most potent at the 5-HT1A receptor, displaying a Ki value of 27 +/- 5 nM. The agent is approximately two to three orders of magnitude less potent at 5-HT2, 5-HT1C, alpha 1-adrenergic, alpha 2-adrenergic, and dopamine D1 and D2 receptors (Ki values ranging from 1300 to 41000 nM). Tandospirone is essentially inactive at 5-HT1B receptors; 5-HT uptake sites; beta-adrenergic, muscarinic cholinergic, and benzodiazepine receptors [1]. 3H-SM-3997 bound rapidly, reversibly and in a saturable manner with high affinity to rat brain hippocampal membranes (Kd = 9.4 nM, Bmax = 213 fmol/mg protein) [2]. in vivo: Chronic treatment with tandospirone, at 0.2 and 1.0mg/kg/day, but not 2.0mg/kg/day, attenuated footshock stress-induced eLAC elevation in the mPFC [3]. Rats were acutely administered tandospirone (0, 0.1, and 1 mg/kg, i.p.). Tandospirone decreased the number of premature responses, an index of impulsive action, in a dose-dependent manner [4]. Toxicity: It is not believed to be addictive but it is known to produce mild withdrawal effects (e.g. anorexia) after abrupt discontinuation.