Exact Mass: 562.2378356

Exact Mass Matches: 562.2378356

Found 1 metabolites which its exact mass value is equals to given mass value 562.2378356, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

SCH529074

SCH529074

C31H36Cl2N6 (562.2378356)


SCH529074 is a potent and orally active p53 activator. SCH529074 binds specifically and conformation-dependently to p53 DBD ( DNA binding domain) with a Ki of 1-2 μM in a saturable manner. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53. SCH529074 can be used for the study of non-small-cell lung carcinoma (NSCLC)[1][2].