Exact Mass: 562.2378356
Exact Mass Matches: 562.2378356
Found 1 metabolites which its exact mass value is equals to given mass value 562.2378356
,
within given mass tolerance error 2.048E-11 dalton. Try search metabolite list with more accurate mass tolerance error
4.096E-12 dalton.
SCH529074
SCH529074
SCH529074 is a potent and orally active p53 activator. SCH529074 binds specifically and conformation-dependently to p53 DBD ( DNA binding domain) with a Ki of 1-2 μM in a saturable manner. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53. SCH529074 can be used for the study of non-small-cell lung carcinoma (NSCLC)[1][2].