Exact Mass: 561.1961126

Exact Mass Matches: 561.1961126

Found 2 metabolites which its exact mass value is equals to given mass value 561.1961126, within given mass tolerance error 8.0E-6 dalton. Try search metabolite list with more accurate mass tolerance error 1.6E-6 dalton.

(2S,3R,4S,5R)-6-Chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro(indole-3,3-pyrrolidine)-5-carboxamide

(2S,3R,4S,5R)-6-Chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-N-(trans-4-hydroxycyclohexyl)-2-oxo-1,2-dihydrospiro(indole-3,3-pyrrolidine)-5-carboxamide

C29H34Cl2FN3O3 (561.1961126)


C274 - Antineoplastic Agent > C129839 - Apoptotic Pathway-targeting Antineoplastic Agent > C162996 - MDM2 Inhibitor

   

MI-773

MI-773

C29H34Cl2FN3O3 (561.1961126)


MI-773 is a potent MDM2-p53 protein‐protein interaction (PPI) inhibitor with high binding affinity against MDM2 (Kd=8.2 nM). MI-773 has antitumor activity[1][2].