Exact Mass: 534.4278
Exact Mass Matches: 534.4278
Found 21 metabolites which its exact mass value is equals to given mass value 534.4278,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
[1-hydroxy-3-[(Z)-tridec-9-enoyl]oxypropan-2-yl] (9Z,12Z)-heptadeca-9,12-dienoate
(1-decanoyloxy-3-hydroxypropan-2-yl) (11Z,14Z,17Z)-icosa-11,14,17-trienoate
[1-hydroxy-3-[(Z)-tetradec-9-enoyl]oxypropan-2-yl] (9Z,12Z)-hexadeca-9,12-dienoate
(1-hydroxy-3-tetradecanoyloxypropan-2-yl) (7Z,10Z,13Z)-hexadeca-7,10,13-trienoate
(1-dodecanoyloxy-3-hydroxypropan-2-yl) (9Z,12Z,15Z)-octadeca-9,12,15-trienoate
(1-hydroxy-3-octanoyloxypropan-2-yl) (10Z,13Z,16Z)-docosa-10,13,16-trienoate
[(2S)-2-decanoyloxy-3-hydroxypropyl] (8E,11E,14E)-icosa-8,11,14-trienoate
[(2S)-1-dodecanoyloxy-3-hydroxypropan-2-yl] (9E,12E,15E)-octadeca-9,12,15-trienoate
[(2S)-2-dodecanoyloxy-3-hydroxypropyl] (9E,12E,15E)-octadeca-9,12,15-trienoate
[3-hydroxy-2-[(E)-tetradec-9-enoyl]oxypropyl] (4E,7E)-hexadeca-4,7-dienoate
[(2S)-1-decanoyloxy-3-hydroxypropan-2-yl] (8E,11E,14E)-icosa-8,11,14-trienoate
(3-hydroxy-2-tetradecanoyloxypropyl) (9E,11E,13E)-hexadeca-9,11,13-trienoate
Pactimibe (sulfate)
C25H40N2O3.1/2H2O4S (534.4278)
Pactimibe sulfate (CS-505) is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe sulfate (CS-505) inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively[1]. Pactimibe sulfate (CS-505) noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe sulfate (CS-505) obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe sulfate (CS-505) possesses anti-atherosclerotic potential with lowering plasma cholesterol activity[2].
