Exact Mass: 529.082217

Exact Mass Matches: 529.082217

Found 1 metabolites which its exact mass value is equals to given mass value 529.082217, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Nebentan (potassium)

Nebentan (potassium)

C24H20KN5O5S (529.082217)


Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan (HY-A0013). Nebentan potassium inhibits [125I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively[1]. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo[2].