Exact Mass: 529.0822

Exact Mass Matches: 529.0822

Found 1 metabolites which its exact mass value is equals to given mass value 529.0822, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Nebentan (potassium)

Nebentan (potassium)

C24H20KN5O5S (529.0822)


Nebentan potassium (YM598) is a potent, selective and orally active non-peptide endothelin ETA receptor antagonist through the modification of Bosentan (HY-A0013). Nebentan potassium inhibits [125I] endothelin-1 binding to cloned human endothelin ETA and ETB receptor, with Ki of 0.697 nM and 569 nM, respectively[1]. YM598 can ameliorate the progression of cor pulmonale and myocardial infarction in vivo[2].