Exact Mass: 524.2832624

Exact Mass Matches: 524.2832624

Found 107 metabolites which its exact mass value is equals to given mass value 524.2832624, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Methyl (2-((R)-(3-chlorophenyl)((R)-1-(((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propyl)carbamoyl)piperidin-3-yl)methoxy)ethyl)carbamate

Methyl (2-((R)-(3-chlorophenyl)((R)-1-(((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propyl)carbamoyl)piperidin-3-yl)methoxy)ethyl)carbamic acid

C26H41ClN4O5 (524.2765326)

Sucrose laurate

2-[3,4-Dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl dodecanoic acid

C24H44O12 (524.2832624)

Sucrose monolaurate

(6-{[3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-3,4,5-trihydroxyoxan-2-yl)methyl dodecanoic acid

C24H44O12 (524.2832624)

Sucrose, 1-laurate

[3,4-Dihydroxy-5-(hydroxymethyl)-2-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxolan-2-yl]methyl dodecanoic acid

C24H44O12 (524.2832624)

Okaramine L

C32H36N4O3 (524.2787266)

Okaramine C

C32H36N4O3 (524.2787266)

An indole alkaloid isolated from Penicillium simplicissimum. It exhibits insecticidal activity.

2alpha-acetyloxy-4beta-hydroxy-6alpha-angeloyloxy-10beta-cinnamoyloxydauc-8-ene|2??-Acetoxy-4??-hydroxy-6??-angeloyloxy-10??-cinnamoyloxy-dauc-8-ene

C31H40O7 (524.2773890000001)

walsucochinoid P

C31H40O7 (524.2773890000001)

C30H40N2O6

C30H40N2O6 (524.288622)

13alpha-acetoxy-5-alpha-cinnamoyloxy-11(15-1)abeotaxa-4(20),11-diene-9alpha,10beta,15-triol

C31H40O7 (524.2773890000001)

12alpha-chloro-2alpha,3beta,13beta,23-tetrahydroxyolean-28-oic acid-13-lactone

C29H45ClO6 (524.29045)

hanliuin II|hanliuine II

C31H40O7 (524.2773890000001)

SLF

C30H40N2O6 (524.288622)

4-dodecanoylsucrose

C24H44O12 (524.2832624)

Okaramine J_120151

C32H36N4O3 (524.2787266)

[3-methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxopentan-2-yl] 2-hydroxy-3-methylpentanoate

NCGC00386071-01![3-methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxopentan-2-yl] 2-hydroxy-3-methylpentanoate

C24H44O12 (524.2832624)

C31H40O7_3,9-Diacetoxy-2,6,6,13-tetramethyl-12-oxotetracyclo[11.2.1.0~1,10~.0~2,7~]hexadec-8-yl benzoate

NCGC00381263-01_C31H40O7_3,9-Diacetoxy-2,6,6,13-tetramethyl-12-oxotetracyclo[11.2.1.0~1,10~.0~2,7~]hexadec-8-yl benzoate

C31H40O7 (524.2773890000001)

[3-methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxopentan-2-yl] 2-hydroxy-3-methylpentanoate [IIN-based on: CCMSLIB00000846977]

NCGC00386071-01![3-methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxopentan-2-yl] 2-hydroxy-3-methylpentanoate [IIN-based on: CCMSLIB00000846977]

C24H44O12 (524.2832624)

[3-methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxopentan-2-yl] 2-hydroxy-3-methylpentanoate [IIN-based: Match]

NCGC00386071-01![3-methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxopentan-2-yl] 2-hydroxy-3-methylpentanoate [IIN-based: Match]

C24H44O12 (524.2832624)

Cys Phe Lys Lys

(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-phenylpropanamido]hexanamido]hexanoic acid

C24H40N6O5S (524.2780750000001)

Cys Lys Phe Lys

(2S)-6-amino-2-[(2S)-2-[(2S)-6-amino-2-[(2R)-2-amino-3-sulfanylpropanamido]hexanamido]-3-phenylpropanamido]hexanoic acid

C24H40N6O5S (524.2780750000001)

Cys Lys Lys Phe

(2S)-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2R)-2-amino-3-sulfanylpropanamido]hexanamido]hexanamido]-3-phenylpropanoic acid

C24H40N6O5S (524.2780750000001)

Phe Cys Lys Lys

(2S)-6-amino-2-[(2S)-6-amino-2-[(2R)-2-[(2S)-2-amino-3-phenylpropanamido]-3-sulfanylpropanamido]hexanamido]hexanoic acid

C24H40N6O5S (524.2780750000001)

Phe Lys Cys Lys

(2S)-6-amino-2-[(2R)-2-[(2S)-6-amino-2-[(2S)-2-amino-3-phenylpropanamido]hexanamido]-3-sulfanylpropanamido]hexanoic acid

C24H40N6O5S (524.2780750000001)

Phe Lys Lys Cys

(2R)-2-[(2S)-6-amino-2-[(2S)-6-amino-2-[(2S)-2-amino-3-phenylpropanamido]hexanamido]hexanamido]-3-sulfanylpropanoic acid

C24H40N6O5S (524.2780750000001)

Gly His Arg Arg

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanoic acid

C20H36N12O5 (524.2931486)

Gly Arg His Arg

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanoic acid

C20H36N12O5 (524.2931486)

Gly Arg Arg His

(2S)-2-[(2S)-2-[(2S)-2-(2-aminoacetamido)-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoic acid

C20H36N12O5 (524.2931486)

His Gly Arg Arg

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]acetamido}-5-carbamimidamidopentanamido]-5-carbamimidamidopentanoic acid

C20H36N12O5 (524.2931486)

His Asn Arg Val

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]-5-carbamimidamidopentanamido]-3-methylbutanoic acid

C21H36N10O6 (524.2819156)

His Asn Val Arg

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]-3-methylbutanamido]-5-carbamimidamidopentanoic acid

C21H36N10O6 (524.2819156)

His Arg Gly Arg

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]acetamido}-5-carbamimidamidopentanoic acid

C20H36N12O5 (524.2931486)

His Arg Asn Val

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]-3-carbamoylpropanamido]-3-methylbutanoic acid

C21H36N10O6 (524.2819156)

His Arg Arg Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]acetic acid

C20H36N12O5 (524.2931486)

His Arg Val Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]-3-methylbutanamido]-3-carbamoylpropanoic acid

C21H36N10O6 (524.2819156)

His Val Asn Arg

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-methylbutanamido]-3-carbamoylpropanamido]-5-carbamimidamidopentanoic acid

C21H36N10O6 (524.2819156)

His Val Arg Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-methylbutanamido]-5-carbamimidamidopentanamido]-3-carbamoylpropanoic acid

C21H36N10O6 (524.2819156)

Lys Cys Phe Lys

(2S)-6-amino-2-[(2S)-2-[(2R)-2-[(2S)-2,6-diaminohexanamido]-3-sulfanylpropanamido]-3-phenylpropanamido]hexanoic acid

C24H40N6O5S (524.2780750000001)

Lys Cys Lys Phe

(2S)-2-[(2S)-6-amino-2-[(2R)-2-[(2S)-2,6-diaminohexanamido]-3-sulfanylpropanamido]hexanamido]-3-phenylpropanoic acid

C24H40N6O5S (524.2780750000001)

Lys Phe Cys Lys

(2S)-6-amino-2-[(2R)-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]-3-phenylpropanamido]-3-sulfanylpropanamido]hexanoic acid

C24H40N6O5S (524.2780750000001)

Lys Phe Lys Cys

(2R)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2,6-diaminohexanamido]-3-phenylpropanamido]hexanamido]-3-sulfanylpropanoic acid

C24H40N6O5S (524.2780750000001)

Lys Lys Cys Phe

(2S)-2-[(2R)-2-[(2S)-6-amino-2-[(2S)-2,6-diaminohexanamido]hexanamido]-3-sulfanylpropanamido]-3-phenylpropanoic acid

C24H40N6O5S (524.2780750000001)

Lys Lys Phe Cys

(2R)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2,6-diaminohexanamido]hexanamido]-3-phenylpropanamido]-3-sulfanylpropanoic acid

C24H40N6O5S (524.2780750000001)

Asn His Arg Val

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]-3-methylbutanoic acid

C21H36N10O6 (524.2819156)

Asn His Val Arg

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-methylbutanamido]-5-carbamimidamidopentanoic acid

C21H36N10O6 (524.2819156)

Asn Arg His Val

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-methylbutanoic acid

C21H36N10O6 (524.2819156)

Asn Arg Val His

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-5-carbamimidamidopentanamido]-3-methylbutanamido]-3-(1H-imidazol-4-yl)propanoic acid

C21H36N10O6 (524.2819156)

Asn Val His Arg

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-methylbutanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanoic acid

C21H36N10O6 (524.2819156)

Asn Val Arg His

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carbamoylpropanamido]-3-methylbutanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoic acid

C21H36N10O6 (524.2819156)

Arg Gly His Arg

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-5-carbamimidamidopentanamido]acetamido}-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanoic acid

C20H36N12O5 (524.2931486)

Arg Gly Arg His

(2S)-2-[(2S)-2-{2-[(2S)-2-amino-5-carbamimidamidopentanamido]acetamido}-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoic acid

C20H36N12O5 (524.2931486)

Arg His Gly Arg

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]acetamido}-5-carbamimidamidopentanoic acid

C20H36N12O5 (524.2931486)

Arg His Asn Val

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]-3-methylbutanoic acid

C21H36N10O6 (524.2819156)

Arg His Arg Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]acetic acid

C20H36N12O5 (524.2931486)

Arg His Val Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-methylbutanamido]-3-carbamoylpropanoic acid

C21H36N10O6 (524.2819156)

Arg Asn His Val

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-3-methylbutanoic acid

C21H36N10O6 (524.2819156)

Arg Asn Val His

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-carbamoylpropanamido]-3-methylbutanamido]-3-(1H-imidazol-4-yl)propanoic acid

C21H36N10O6 (524.2819156)

Arg Arg Gly His

(2S)-2-{2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]acetamido}-3-(1H-imidazol-4-yl)propanoic acid

C20H36N12O5 (524.2931486)

Arg Arg His Gly

2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]acetic acid

C20H36N12O5 (524.2931486)

Arg Val His Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-methylbutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanoic acid

C21H36N10O6 (524.2819156)

Arg Val Asn His

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-methylbutanamido]-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanoic acid

C21H36N10O6 (524.2819156)

Val His Asn Arg

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanamido]-5-carbamimidamidopentanoic acid

C21H36N10O6 (524.2819156)

Val His Arg Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanamido]-3-carbamoylpropanoic acid

C21H36N10O6 (524.2819156)

Val Asn His Arg

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanamido]-5-carbamimidamidopentanoic acid

C21H36N10O6 (524.2819156)

Val Asn Arg His

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-carbamoylpropanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanoic acid

C21H36N10O6 (524.2819156)

Val Arg His Asn

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-5-carbamimidamidopentanamido]-3-(1H-imidazol-4-yl)propanamido]-3-carbamoylpropanoic acid

C21H36N10O6 (524.2819156)

Val Arg Asn His

(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-5-carbamimidamidopentanamido]-3-carbamoylpropanamido]-3-(1H-imidazol-4-yl)propanoic acid

C21H36N10O6 (524.2819156)

Synthetic Ligand of FKBP

(1R)-1-(3-aminophenyl)-3-(3,4-dimethoxyphenyl)propyl ester-1-(3,3-dimethyl-1,2-dioxopentyl)-2S-piperidinecarboxylic acid

C30H40N2O6 (524.288622)

3,9-Diacetoxy-2,6,6,13-tetramethyl-12-oxotetracyclo[11.2.1.01,10.02,7]hexadec-8-yl benzoate

C31H40O7 (524.2773890000001)

PG-PA

1-hexadecanoyl-2-glutaryl-sn-glycero-3-phosphate

C24H45O10P (524.2750199999999)

1,3-BIS[BIS(3,5-DIMETHYLPHENYL)PHOSPHINO]PROPANE

C35H42P2 (524.2761592)

VTP-27999

Methyl (2-((R)-(3-chlorophenyl)((R)-1-(((S)-2-(methylamino)-3-((R)-tetrahydro-2H-pyran-3-yl)propyl)carbamoyl)piperidin-3-yl)methoxy)ethyl)carbamate

C26H41ClN4O5 (524.2765326)

sucrose monolaurate

C24H44O12 (524.2832624)

Propargyl-PEG10-acid

C24H44O12 (524.2832624)

alpha-d-Glucopyranoside, beta-d-fructofuranosyl, dodecanoate

C24H44O12 (524.2832624)

lauroyl(-1)Hex2ulof(?2-1?)Hex

C24H44O12 (524.2832624)

N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-sn-glycero-3-phosphoethanolamine(1-)

C27H43NO7P- (524.2776998)

(3S)-3beta-[2-(1,1-Dimethyl-2-propenyl)-1H-indole-3-ylmethyl]-6-(1,1-dimethyl-2-propenyl)-2,3,4,5aalpha,6,10b,11,11aalpha-octahydro-10balpha-hydroxy-1H-pyrazino[1,2:1,5]pyrrolo[2,3-b]indole-1,4-dione

C32H36N4O3 (524.2787266)

[3-Methyl-1-[3-methyl-1-oxo-1-(2,3,4,5,6-pentahydroxyhexoxy)pentan-2-yl]oxy-1-oxopentan-2-yl] 2-hydroxy-3-methylpentanoate

C24H44O12 (524.2832624)

(+)-Okaramine J

C32H36N4O3 (524.2787266)

2-[[(2Z,5Z)-6-[[(2E,4E,10E)-7,9-dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoyl]amino]hexa-2,5-dienoyl]amino]acetic acid

C30H40N2O6 (524.288622)

[1-[(2-acetyloxy-3-hydroxypropoxy)-hydroxyphosphoryl]oxy-3-hydroxypropan-2-yl] (Z)-hexadec-9-enoate

C24H45O10P (524.2750199999999)

[1-hydroxy-3-[hydroxy-(3-hydroxy-2-propanoyloxypropoxy)phosphoryl]oxypropan-2-yl] (Z)-pentadec-9-enoate

C24H45O10P (524.2750199999999)

[1-[(2-butanoyloxy-3-hydroxypropoxy)-hydroxyphosphoryl]oxy-3-hydroxypropan-2-yl] (Z)-tetradec-9-enoate

C24H45O10P (524.2750199999999)

[1-hydroxy-3-[hydroxy-(3-hydroxy-2-pentanoyloxypropoxy)phosphoryl]oxypropan-2-yl] (Z)-tridec-9-enoate

C24H45O10P (524.2750199999999)

[1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-pentanoyloxypropan-2-yl] (Z)-tridec-9-enoate

C24H45O10P (524.2750199999999)

[1-butanoyloxy-3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxypropan-2-yl] (Z)-tetradec-9-enoate

C24H45O10P (524.2750199999999)

[1-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-3-propanoyloxypropan-2-yl] (Z)-pentadec-9-enoate

C24H45O10P (524.2750199999999)

[1-acetyloxy-3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxypropan-2-yl] (Z)-hexadec-9-enoate

C24H45O10P (524.2750199999999)

PA 16:0/5:1;O2

C24H45O10P (524.2750199999999)

LPG 18:2;O

C24H45O10P (524.2750199999999)

PG 14:0/4:1

C24H45O10P (524.2750199999999)

PG 14:1/4:0

C24H45O10P (524.2750199999999)

PG 16:1/2:0

C24H45O10P (524.2750199999999)

PG 18:1

C24H45O10P (524.2750199999999)

PG 18:1(9Z)/0:0

C24H45O10P (524.2750199999999)

PG 2:0_16:1

C24H45O10P (524.2750199999999)

LPEth 23:6

C28H45O7P (524.290275)

LPM 24:6

C28H45O7P (524.290275)

ST 25:6;O;GlcA

C31H40O7 (524.2773890000001)

ST 25:7;O2;Hex

C31H40O7 (524.2773890000001)

ST 28:3;O4;S

C28H44O7S (524.2807594)

BIBS 39

C32H36N4O3 (524.2787266)

BIBS 39 is a new nonpeptide angiotensin II (AII) receptor antagonist. Target: Angiotensin Receptor in vitro: BIBS 39 displaces [125I] AII from its specific binding sites with a Ki value of 29 ± 7 nM for the AII subtype 1 (AT1) receptor and a Ki value of 480 ± 110 nM for the AII subtype 2 (AT2) receptor. BIBS 222 shows a Ki value of 20 ± 7 nM for the AT1 subtype and a Ki value of 730 ± 170 nM for the AT2 subtype. BIBS 39 is 17 times more selective for the AT1 subtype and BIBS 222 37 times. BIBS 39 shifts the AII concentration-contractile response curves in isolated rabbit aorta to the right in a parallel fashion. [1] in vivo: In pithed rats, BIBS 39 dependently shifts the dose-response curve of AII to the right without affecting the maximal response. BIBS 222 also causes parallel shifts to the right but a significant reduction of the maximal responses was observed at 3 and 10 mg/kg i.v. These results show that the benzimidazole derivatives BIBS 39 is a potent and selective AII receptor antagonists. Substitution with a benzimidazole moiety results into a considerable loss of selectivity for the AT1 receptor subtype compared with an imidazole moiety as, for instance, in DuP 753.[1] BIBS 39 is a new nonpeptide angiotensin receptor blockers that has affinity for both AT1- and AT2-receptors, is also a potent antagonist of the cardiovascular effects of AII in pithed rabbits. [2]