Exact Mass: 518.186
Exact Mass Matches: 518.186
Found 3 metabolites which its exact mass value is equals to given mass value 518.186,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
Poly-g-D-glutamate
Poly-gamma-D-glutamate or PGA is an intermediate in D-Glutamine and D-glutamate metabolism. It is a polymer of D-glutamate residues. It is produced by bacteria, a number of which are part of the normal human microflora. In particular, Staph. epidermidis secretes poly-gamma-glutamate (PGA) to facilitate growth and ensure its survival inside the human host. PGA protects the pathogen from innate host defenses during infection. S. epidermidis is the only human pathogen known to produce PGA other than Bacillus anthracis, but several differences exist in how the two pathogens use PGA to their advantage. What is shown in the attached diagram is a tetramer of poly-gamma-glutamate. PGA is currently used as an antigen for vaccine production against Anthrax. Poly-gamma-D-glutamate is produced from L-Glutamate via a multi-step reaction. [HMDB] Poly-gamma-D-glutamate or PGA is an intermediate in D-Glutamine and D-glutamate metabolism. It is a polymer of D-glutamate residues. It is produced by bacteria, a number of which are part of the normal human microflora. In particular, Staph. epidermidis secretes poly-gamma-glutamate (PGA) to facilitate growth and ensure its survival inside the human host. PGA protects the pathogen from innate host defenses during infection. S. epidermidis is the only human pathogen known to produce PGA other than Bacillus anthracis, but several differences exist in how the two pathogens use PGA to their advantage. What is shown in the attached diagram is a tetramer of poly-gamma-glutamate. PGA is currently used as an antigen for vaccine production against Anthrax. Poly-gamma-D-glutamate is produced from L-Glutamate via a multi-step reaction.
