Exact Mass: 516.1708
Exact Mass Matches: 516.1708
Found 132 metabolites which its exact mass value is equals to given mass value 516.1708
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Rottlerin
Rottlerin is a chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis. It has a role as an antineoplastic agent, an apoptosis inducer, a metabolite, a K-ATP channel agonist, an antihypertensive agent and an anti-allergic agent. It is an enone, a chromenol, a benzenetriol, a methyl ketone and an aromatic ketone. Rottlerin is a natural product found in Mallotus philippensis with data available. A chromenol that is 2,2-dimethyl-2H-chromene substituted by hydroxy groups at positions 5 and 7, a 3-acetyl-2,4,6-trihydroxy-5-methylbenzyl group at position 6 and a (1E)-3-oxo-1-phenylprop-1-en-3-yl group at position 8. A potassium channel opener, it is isolated from Mallotus philippensis. D004791 - Enzyme Inhibitors relative retention time with respect to 9-anthracene Carboxylic Acid is 1.546 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.549 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.548 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.550 Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin induces apoptosis via caspase 3 activation[1][2][3]. Rottlerin inhibits HIV-1 integration and Rabies virus (RABV) infection[4][5]. Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin induces apoptosis via caspase 3 activation[1][2][3]. Rottlerin inhibits HIV-1 integration and Rabies virus (RABV) infection[4][5].
Luteone 7-glucoside
Luteone 7-glucoside is found in pulses. Luteone 7-glucoside is isolated from the roots of Lupinus albus (white lupin). Isolated from the roots of Lupinus albus (white lupin). Luteone 7-glucoside is found in pulses and white lupine.
((2R,3S,4S,5R,6S)-6-(2-(3-(Benzofuran-5-yl)propanoyl)-3-hydroxy-5-methylphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl methyl carbonate
1-[6-[(3-Acetyl-2,4,6-trihydroxy-5-methylphenyl)methyl]-5,7-dihydroxy-2,2-dimethyl-1-benzopyran-8-yl]-3-phenyl-2-propen-1-one
Epimedoside C
5alpha,6beta,7beta,8alpha-tetraacetoxy-2-<2-(4-methoxyphenyl)ethyl>-5,6,7,8-tetrahydrochromone|5alpha,6beta,7beta,8alpha-tetraacetoxy-2-[2-(4-methoxyphenyl)ethyl]-5,6,7,8-tetrahydrochromone|5??,6??,7??,8??-Tetraacetoxy-2-[2-(4-methoxyphenyl)ethyl]-5,6,7,8-tetrahydro-chromone
6-gamma,gamma-dimethylallylkaempferol 7-O-beta-D-glucoside
5,7,3,4-tetrahydroxy-5-C-prenylflavone 7-O-beta-D-glucopyranoside
alpha-L-Rhap-(1 -> 4)-beta-D-GlcpA-(1 -> 6)-alphabeta-D-Galp
21-oxo-23S-hydroxy-21,23-dihydroevodol|euodirutaecin A
23-oxo-21S-hydroxy-21,23-dihydroevodol|evodirutaenin A
5,4-dihydroxy-7-O-beta-D-pyranglycuronate butyl ester
2-(3,4-dihydroxyphenyl)ethyl 4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-hydroxy-4a,5,7,7a-tetrahydro-4H-furo[3,4-b]pyran-3-carboxylate
2-(3,4-dihydroxyphenyl)ethyl 4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-hydroxy-4a,5,7,7a-tetrahydro-4H-furo[3,4-b]pyran-3-carboxylate [IIN-based on: CCMSLIB00000847426]
2-(3,4-dihydroxyphenyl)ethyl 4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-hydroxy-4a,5,7,7a-tetrahydro-4H-furo[3,4-b]pyran-3-carboxylate [IIN-based: Match]
Cys Glu Glu His
Cys Glu His Glu
Cys His Glu Glu
Cys Met Thr Tyr
Cys Met Tyr Thr
Cys Thr Met Tyr
Cys Thr Tyr Met
Cys Tyr Met Thr
Cys Tyr Thr Met
Asp Asp His Met
Asp Asp Met His
Asp His Asp Met
Asp His Met Asp
Asp Met Asp His
Asp Met His Asp
Glu Cys Glu His
Glu Cys His Glu
Glu Glu Cys His
Glu Glu His Cys
Glu His Cys Glu
Glu His Glu Cys
His Cys Glu Glu
His Asp Asp Met
His Asp Met Asp
His Glu Cys Glu
His Glu Glu Cys
His Met Asp Asp
Met Cys Thr Tyr
Met Cys Tyr Thr
Met Asp Asp His
Met Asp His Asp
Met His Asp Asp
Met Thr Cys Tyr
Met Thr Tyr Cys
Met Tyr Cys Thr
Met Tyr Thr Cys
Thr Cys Met Tyr
Thr Cys Tyr Met
Thr Met Cys Tyr
Thr Met Tyr Cys
Thr Tyr Cys Met
Thr Tyr Met Cys
Tyr Cys Met Thr
Tyr Cys Thr Met
Tyr Met Cys Thr
Tyr Met Thr Cys
Tyr Thr Cys Met
Tyr Thr Met Cys
Luteone 7-glucoside
4-[[5-(anilino)carbonyl-2-methoxyphenyl]azo]-3-hydroxy-N-phenylnaphthalene-2-carboxamide
5-[[[(2,4-Difluorophenyl)methyl]amino]carbonyl]-1-(2,2-dimethoxyethyl)-1,4-dihydro-4-oxo-3-(phenylmethoxy)-2-pyridinecarboxylic acid methyl ester
N-Acetyl-9-azido-9-deoxyneuraminic acid methyl ester 2,4,7,8-tetraacetate
Maltosyl-alpha (1,4)-(Z,3S,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-piperidin-2-one oxime
Cys-Met-Thr-Tyr
A tetrapeptide composed of L-cysteine, L-methionine, L-threonine and L-tyrosine joined in sequence by peptide linkages.