Exact Mass: 509.0335

Exact Mass Matches: 509.0335

Found 2 metabolites which its exact mass value is equals to given mass value 509.0335, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

(-)-Bicuculline methiodide

(-)-Bicuculline methiodide

C21H20INO6 (509.0335)


   

Bicuculline methiodide

Bicuculline methiodide

C21H20INO6 (509.0335)


Bicuculline methiodide is a potent GABA(A) receptors blocker. Bicuculline methiodide alters membrane properties and firing pattern. Bicuculline methiodide reduces the Apamin-sensitive afterhyperpolarization, while Apamin is a toxin isolated from bee venom to block small conductance Ca2+ -activated K+ channels. Bicuculline methiodide facilitates burst firing via blocking apamin-sensitive Ca2+ -activated K+ current[1].