Exact Mass: 503.132207
Exact Mass Matches: 503.132207
Found 6 metabolites which its exact mass value is equals to given mass value 503.132207
,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
1-Decyl-3-Methylimidazolium Bis(Trifluoromethylsulfonyl)Imide
YH239-EE
C25H27Cl2N3O4 (503.13785220000005)
YH239-EE, ethyl ester of the free carboxylic acid compound YH239, is a potent p53-MDM2 antagonizing and apoptosis-inducing agent. IC50 value: Target: MDM2/p53 YH239-EE inhibits the growth of OCI-AML-3 cells with wild type p53 by inhibiting the p53-MDM2 interaction. YH239-EE induces cell cycle arrest and causes potent cell apoptosis via activation of p53 and downstream targets in four AML cells (OCI-AML-3 and MOLM-13 with wt p53, NB4 with p53 mutation, and HL60 with p53 deletion).