Exact Mass: 501.2185

Exact Mass Matches: 501.2185

Found 15 metabolites which its exact mass value is equals to given mass value 501.2185, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Asp Asp Pro Arg

(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoic acid

C19H31N7O9 (501.2183)


   

Asp Asp Arg Pro

(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-3-carboxypropanamido]-5-carbamimidamidopentanoyl]pyrrolidine-2-carboxylic acid

C19H31N7O9 (501.2183)


   

Asp Pro Asp Arg

(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-5-carbamimidamidopentanoic acid

C19H31N7O9 (501.2183)


   

Asp Pro Arg Asp

(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanamido]butanedioic acid

C19H31N7O9 (501.2183)


   

Asp Arg Asp Pro

(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-carbamimidamidopentanamido]-3-carboxypropanoyl]pyrrolidine-2-carboxylic acid

C19H31N7O9 (501.2183)


   

Asp Arg Pro Asp

(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-3-carboxypropanamido]-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}butanedioic acid

C19H31N7O9 (501.2183)


   

Pro Asp Asp Arg

(2S)-5-carbamimidamido-2-[(2S)-3-carboxy-2-[(2S)-3-carboxy-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]propanamido]pentanoic acid

C19H31N7O9 (501.2183)


   

Pro Asp Arg Asp

(2S)-2-[(2S)-5-carbamimidamido-2-[(2S)-3-carboxy-2-[(2S)-pyrrolidin-2-ylformamido]propanamido]pentanamido]butanedioic acid

C19H31N7O9 (501.2183)


   

Pro Arg Asp Asp

(2S)-2-[(2S)-2-[(2S)-5-carbamimidamido-2-[(2S)-pyrrolidin-2-ylformamido]pentanamido]-3-carboxypropanamido]butanedioic acid

C19H31N7O9 (501.2183)


   

Arg Asp Asp Pro

(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-carboxypropanamido]-3-carboxypropanoyl]pyrrolidine-2-carboxylic acid

C19H31N7O9 (501.2183)


   

Arg Asp Pro Asp

(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}butanedioic acid

C19H31N7O9 (501.2183)


   

Arg Pro Asp Asp

(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-amino-5-carbamimidamidopentanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]butanedioic acid

C19H31N7O9 (501.2183)


   
   

(S,R)-GSK321

(S,R)-GSK321

C28H28FN5O3 (501.2176)


(S,R)-GSK321 is a potent, selective mutant IDH1 inhibitor with IC50 values of 2.9, 3.8, 4.6 and 46 nM for R132G, R132C, R132H and WT IDH1, respectively, and >100-fold selectivity over IDH2. (S,R)-GSK321 induces decrease in intracellular 2-HG, abrogation of the myeloid differentiation block and induction of granulocytic differentiation at the level of leukemic blasts and more immature stem-like cells. (S,R)-GSK321can be used for research of acute myeloid leukemia (AML) and other cancers[1].

   

GSK321

GSK321

C28H28FN5O3 (501.2176)


GSK321 is a potent inhibitor of mutant isocitrate dehydrogenase 1 (IDH1) enzymes. GSK321 has high inhibitory and selectivity for mutant IDH1 enzymes. GSK321 can be used for the research of acute myeloid leukemia[1][2].