Exact Mass: 500.1894
Exact Mass Matches: 500.1894
Found 21 metabolites which its exact mass value is equals to given mass value 500.1894,
within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error
0.0002 dalton.
Rolapitant
(5S,8S)-8-[[[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl]oxy]methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one
2-((Z)-hepta-5-en-1,3-diynyl)tetrahydrofuran-2-beta-D-glucopyranosyl(1->2)-beta-D-glucopyranoside|panaxfurayne B
2-((Z)-hepta-5-en-1,3-diynyl)tetrahydrofuran-2-beta-D-glucopyranosyl(1->2)-beta-D-glucopyranoside|panaxfurayne B
O-Rutinoside-3-(3-Hydroxypropyl)phthalide|Pedirutinoside
O-Rutinoside-3-(3-Hydroxypropyl)phthalide|Pedirutinoside
(1R,2S,4S,5S,6R,7R,9S,10S)-1,2,9,15-tetraacetoxy-4,6-dihydroxy-8-oxodihydro-beta-agarofuran
(1R,2S,4S,5S,6R,7R,9S,10S)-1,2,9,15-tetraacetoxy-4,6-dihydroxy-8-oxodihydro-beta-agarofuran
rolapitant
rolapitant
A - Alimentary tract and metabolism > A04 - Antiemetics and antinauseants > A04A - Antiemetics and antinauseants D018377 - Neurotransmitter Agents > D064729 - Neurokinin-1 Receptor Antagonists C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a Ki of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model[1][2].
[(1s,2s,4s,5r,6s,7s,9r,12r)-4,5,7-tris(acetyloxy)-2,12-dihydroxy-2,10,10-trimethyl-8-oxo-11-oxatricyclo[7.2.1.0¹,⁶]dodecan-6-yl]methyl acetate
[(1s,2s,4s,5r,6s,7s,9r,12r)-4,5,7-tris(acetyloxy)-2,12-dihydroxy-2,10,10-trimethyl-8-oxo-11-oxatricyclo[7.2.1.0¹,⁶]dodecan-6-yl]methyl acetate
1-(3,5-dihydroxy-2-{[(4-methoxy-4-oxobutan-2-yl)oxy]carbonyl}phenyl)propan-2-yl 4-hydroxy-3-[(3-hydroxybutanoyl)oxy]butanoate
1-(3,5-dihydroxy-2-{[(4-methoxy-4-oxobutan-2-yl)oxy]carbonyl}phenyl)propan-2-yl 4-hydroxy-3-[(3-hydroxybutanoyl)oxy]butanoate
(2s,3r,4s,5s,6r)-2-{[(2s,3r,4s,5s,6r)-2-{[(2r)-2-[(5z)-hept-5-en-1,3-diyn-1-yl]oxolan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
(2s,3r,4s,5s,6r)-2-{[(2s,3r,4s,5s,6r)-2-{[(2r)-2-[(5z)-hept-5-en-1,3-diyn-1-yl]oxolan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
(2s,3r,4s,5s,6r)-2-{[(2s,3r,4s,5s,6r)-2-{[(2r)-2-[(5e)-hept-5-en-1,3-diyn-1-yl]oxolan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
(2s,3r,4s,5s,6r)-2-{[(2s,3r,4s,5s,6r)-2-{[(2r)-2-[(5e)-hept-5-en-1,3-diyn-1-yl]oxolan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
[4,5,7-tris(acetyloxy)-2,12-dihydroxy-2,10,10-trimethyl-8-oxo-11-oxatricyclo[7.2.1.0¹,⁶]dodecan-6-yl]methyl acetate
[4,5,7-tris(acetyloxy)-2,12-dihydroxy-2,10,10-trimethyl-8-oxo-11-oxatricyclo[7.2.1.0¹,⁶]dodecan-6-yl]methyl acetate
3-[(3s)-3-{[(2r,3r,4s,5s,6r)-6-({[(2r,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}butyl]-3h-2-benzofuran-1-one
3-[(3s)-3-{[(2r,3r,4s,5s,6r)-6-({[(2r,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl]oxy}butyl]-3h-2-benzofuran-1-one
[(3s,4s,5s)-5-{[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-hydroxyphenoxy)oxan-3-yl]oxy}-3,4-dihydroxyoxolan-3-yl]methyl (2e)-hex-2-enoate
[(3s,4s,5s)-5-{[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-hydroxyphenoxy)oxan-3-yl]oxy}-3,4-dihydroxyoxolan-3-yl]methyl (2e)-hex-2-enoate
(5-{[4,5-dihydroxy-6-(hydroxymethyl)-2-(4-hydroxyphenoxy)oxan-3-yl]oxy}-3,4-dihydroxyoxolan-3-yl)methyl hex-2-enoate
(5-{[4,5-dihydroxy-6-(hydroxymethyl)-2-(4-hydroxyphenoxy)oxan-3-yl]oxy}-3,4-dihydroxyoxolan-3-yl)methyl hex-2-enoate
2-[(2-{[2-(hept-5-en-1,3-diyn-1-yl)oxolan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
2-[(2-{[2-(hept-5-en-1,3-diyn-1-yl)oxolan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
4-{[1-(3,5-dihydroxy-2-{[(4-methoxy-4-oxobutan-2-yl)oxy]carbonyl}phenyl)propan-2-yl]oxy}-4-oxobutan-2-yl 3,4-dihydroxybutanoate
4-{[1-(3,5-dihydroxy-2-{[(4-methoxy-4-oxobutan-2-yl)oxy]carbonyl}phenyl)propan-2-yl]oxy}-4-oxobutan-2-yl 3,4-dihydroxybutanoate
[(3r,4s,5r)-5-{[(2r,3s,4r,5r,6s)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-hydroxyphenoxy)oxan-3-yl]oxy}-3,4-dihydroxyoxolan-3-yl]methyl (2e)-hex-2-enoate
[(3r,4s,5r)-5-{[(2r,3s,4r,5r,6s)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-hydroxyphenoxy)oxan-3-yl]oxy}-3,4-dihydroxyoxolan-3-yl]methyl (2e)-hex-2-enoate
[(3s,4r,5s)-5-{[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-hydroxyphenoxy)oxan-3-yl]oxy}-3,4-dihydroxyoxolan-3-yl]methyl (2e)-hex-2-enoate
[(3s,4r,5s)-5-{[(2s,3r,4s,5s,6r)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-hydroxyphenoxy)oxan-3-yl]oxy}-3,4-dihydroxyoxolan-3-yl]methyl (2e)-hex-2-enoate
