Exact Mass: 499.1049

Exact Mass Matches: 499.1049

Found 4 metabolites which its exact mass value is equals to given mass value 499.1049, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

VX-11e

4-{2-[(2-Chloro-4-Fluorophenyl)amino]-5-Methylpyrimidin-4-Yl}-N-[(1s)-1-(3-Chlorophenyl)-2-Hydroxyethyl]-1h-Pyrrole-2-Carboxamide

C24H20Cl2FN5O2 (499.0978)


VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK with Ki < 2 nM.

   

4-nitrobenzyl [2R-(2alpha,5beta,6alpha,7beta)]-3-methylene-8-oxo-7-(phenoxyacetamido)-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylate 5-oxide

4-nitrobenzyl [2R-(2alpha,5beta,6alpha,7beta)]-3-methylene-8-oxo-7-(phenoxyacetamido)-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylate 5-oxide

C23H21N3O8S (499.1049)


   

[4-(2-Chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(phenylmethyl)-1-piperazinyl]methanone

[4-(2-Chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(phenylmethyl)-1-piperazinyl]methanone

C24H22ClN3O5S (499.0969)


   

(R)-VX-11e

(R)-VX-11e

C24H20Cl2FN5O2 (499.0978)


(R)-VX-11e (Compound 1) is an ERK2 inhibitor[1].