Exact Mass: 499.0969

Exact Mass Matches: 499.0969

Found 3 metabolites which its exact mass value is equals to given mass value 499.0969, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

VX-11e

4-{2-[(2-Chloro-4-Fluorophenyl)amino]-5-Methylpyrimidin-4-Yl}-N-[(1s)-1-(3-Chlorophenyl)-2-Hydroxyethyl]-1h-Pyrrole-2-Carboxamide

C24H20Cl2FN5O2 (499.0978)


VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK with Ki < 2 nM.

   

[4-(2-Chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(phenylmethyl)-1-piperazinyl]methanone

[4-(2-Chlorophenyl)sulfonyl-3-nitrophenyl]-[4-(phenylmethyl)-1-piperazinyl]methanone

C24H22ClN3O5S (499.0969)


   

(R)-VX-11e

(R)-VX-11e

C24H20Cl2FN5O2 (499.0978)


(R)-VX-11e (Compound 1) is an ERK2 inhibitor[1].