Exact Mass: 498.24309179999995

Exact Mass Matches: 498.24309179999995

Found 1 metabolites which its exact mass value is equals to given mass value 498.24309179999995, within given mass tolerance error 2.56E-9 dalton. Try search metabolite list with more accurate mass tolerance error 5.12E-10 dalton.

Mutant IDH1-IN-1

Mutant IDH1-IN-1

C30H31FN4O2 (498.24309179999995)


Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively.