Exact Mass: 496.176278

Exact Mass Matches: 496.176278

Found 4 metabolites which its exact mass value is equals to given mass value 496.176278, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

   
   
   

BMS-309403 (sodium)

BMS-309403 (sodium)

C31H25N2NaO3 (496.176278)


BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 sodium interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 sodium improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells[1][2][3].