Exact Mass: 495.15472940000006

Exact Mass Matches: 495.15472940000006

Found 1 metabolites which its exact mass value is equals to given mass value 495.15472940000006, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

R 59-022 (hydrochloride)

R 59-022 (hydrochloride)

C27H27ClFN3OS (495.15472940000006)


R 59-022 (DKGI-I) hydrochloride is a DGK inhibitor (IC50: 2.8 μM). R 59-022 hydrochloride inhibits the phosphorylation of OAG to OAPA. R 59-022 hydrochloride is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 hydrochloride potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4].