Exact Mass: 494.1599

Exact Mass Matches: 494.1599

Found 1 metabolites which its exact mass value is equals to given mass value 494.1599, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

ML380

ML380

C23H25F3N4O3S (494.1599)


ML380 is a potent, subtype-selective, and brain-penetrant positive allosteric modulator (PAM) of M5 mAChR, with EC50s of 190 and 610 nM for human and rat M5, respectively. ML380 exhibits moderate selectivity versus the M1 and M3 mAChR subtypes. ML380 could increase the affinity of ACh for the M5 mAChR[1][2][3].