Exact Mass: 490.2169

Exact Mass Matches: 490.2169

Found 1 metabolites which its exact mass value is equals to given mass value 490.2169, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Tenovin-6 (Hydrochloride)

Tenovin-6 (Hydrochloride)

C25H35ClN4O2S (490.2169)


Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH)[1][2].